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Clinical Reviews in Allergy & Immunology

Published in:

01-12-2014

Quantitative Peripheral Blood Perturbations of γδ T Cells in Human Disease and Their Clinical Implications

Authors: Ilan Bank, Victoria Marcu-Malina

Published in: Clinical Reviews in Allergy & Immunology | Issue 3/2014

Abstract

Human γδ T cells, which play innate and adaptive, protective as well as destructive, roles in the immune response, were discovered in 1986, but the clinical significance of alterations of the levels of these cells in the peripheral blood in human diseases has not been comprehensively reviewed. Here, we review patterns of easily measurable changes of this subset of T cells in peripheral blood from relevant publications in PubMed and their correlations with specific disease categories, specific diagnoses within disease categories, and prognostic outcomes. These collective data suggest that enumeration of γδ T cells and their subsets in the peripheral blood of patients could be a useful tool to evaluate diagnosis and prognosis in the clinical setting.

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Title: Quantitative Peripheral Blood Perturbations of γδ T Cells in Human Disease and Their Clinical Implications
Authors: Ilan Bank
Victoria Marcu-Malina
Publication date: 01-12-2014
Publisher: Springer US
Published in: Clinical Reviews in Allergy & Immunology / Issue 3/2014
Print ISSN: 1080-0549
Electronic ISSN: 1559-0267
DOI: https://doi.org/10.1007/s12016-013-8391-x

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