Top

Acta Neuropathologica Communications

Published in:

Open Access 01-12-2023 | Letter to the Editor

Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN

Authors: Maddalena M. Bolognesi, Asier Antoranz, Francesca Maria Bosisio, Giorgio Cattoretti

Published in: Acta Neuropathologica Communications | Issue 1/2023

Excerpt

Dear Editor, …

Shahidehpour RK, Nelson AS, Sanders LG, Embry CR, Nelson PT, Bachstetter AD (2023) The localization of molecularly distinct microglia populations to Alzheimer’s disease pathologies using QUIVER. Acta Neuropathol Commun 11(1):45. https://doi.org/10.1186/s40478-023-01541-wCrossRefPubMedPubMedCentral

Bolognesi MM, Manzoni M, Scalia CR et al (2017) Multiplex staining by sequential immunostaining and antibody removal on routine tissue sections. J Histochem Cytochem 65(8):431–444. https://doi.org/10.1369/0022155417719419CrossRefPubMedPubMedCentral

Schubert W, Bonnekoh B, Pommer AJ et al (2006) Analyzing proteome topology and function by automated multidimensional fluorescence microscopy. Nat Biotechnol 24(10):1270–1278. https://doi.org/10.1038/nbt1250CrossRefPubMed

Lin J-R, Fallahi-Sichani M, Sorger PK (2015) Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method. Nat Commun 6:8390. https://doi.org/10.1038/ncomms9390CrossRefPubMed

Kinkhabwala A, Herbel C, Pankratz J et al (2022) MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors. Sci Rep 03(1):1911–1916. https://doi.org/10.1038/s41598-022-05841-4CrossRef

Goltsev Y, Samusik N, Kennedy-Darling J et al (2018) Deep profiling of mouse Splenic architecture with CODEX multiplexed imaging. Cell 09(4):968-981e15. https://doi.org/10.1016/j.cell.2018.07.010CrossRef

Remark R, Merghoub T, Grabe N et al (2016) In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide. Sci Immunol 14(1):aaf6925. https://doi.org/10.1126/sciimmunol.aaf6925CrossRef

De Smet F, Antoranz Martinez A, Bosisio FM (2021) Next-generation pathology by multiplexed immunohistochemistry. Trends Biochem Sci 46(1):80–82. https://doi.org/10.1016/j.tibs.2020.09.009CrossRefPubMed

Glass G, Papin JA, Mandell JW (2009) SIMPLE: a sequential immunoperoxidase labeling and erasing method. J Histochem Cytochem 57(10):899–905. https://doi.org/10.1369/jhc.2009.953612CrossRefPubMedPubMedCentral

10.

Eng J, Bucher E, Hu Z et al (2022) A framework for multiplex imaging optimization and reproducible analysis. Commun Biol 11(1):438. https://doi.org/10.1038/s42003-022-03368-yCrossRef

11.

Gendusa R, Scalia CR, Buscone S, Cattoretti G (2014) Elution of high-affinity (> 10 – 9 KD) antibodies from tissue sections: clues to the molecular mechanism and use in sequential immunostaining. J Histochem Cytochem 02(7):519–531. https://doi.org/10.1369/0022155414536732CrossRef

12.

Scalia CR, Boi G, Bolognesi MM et al (2017) Antigen masking during fixation and embedding, dissected. J Histochem Cytochem 65(1):5–20. https://doi.org/10.1369/0022155416673995CrossRefPubMed

13.

Banik G, Betts CB, Liudahl SM et al (2020) High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers. Methods Enzymol 635:1–20. https://doi.org/10.1016/bs.mie.2019.05.039CrossRefPubMed

14.

Cattoretti G, Bosisio F, Marcelis L, Bolognesi MM (2019) Multiple iterative labeling by antibody neodeposition (MILAN). Nat Res. https://protocolexchange.researchsquare.com/article/nprot-7017/v5

15.

Bosisio FM, Antoranz A, van Herck Y et al (2020) Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing. Elife. https://doi.org/10.7554/eLife.53008CrossRefPubMedPubMedCentral

16.

Manzoni M, Bolognesi MM, Antoranz A et al (2020) The adaptive and innate immune cell landscape of uterine leiomyosarcomas. Sci Rep 10(1):702–10. https://doi.org/10.1038/s41598-020-57627-1CrossRefPubMedPubMedCentral

17.

Furia L, Pelicci S, Perillo F et al (2022) Automated multimodal fluorescence microscopy for hyperplex spatial-proteomics: coupling microfluidic-based immunofluorescence to high resolution, high sensitivity, three-dimensional analysis of histological slides. Front Oncol 12:960734. https://doi.org/10.3389/fonc.2022.960734CrossRefPubMedPubMedCentral

18.

Ciccimarra R, Bolognesi MM, Zoboli M, Cattoretti G, Stellari FF, Ravanetti F (2022) The normal and fibrotic mouse lung classified by spatial proteomic analysis. Sci Rep 24(1):8742. https://doi.org/10.1038/s41598-022-12738-9CrossRef

19.

Frias A, Di Leo L, Antoranz A et al (2023) Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma. J Immunother Cancer. https://doi.org/10.1136/jitc-2022-006389CrossRefPubMedPubMedCentral

20.

Ehrenberg AJ, Morales DO, Piergies AMH et al (2020) A manual multiplex immunofluorescence method for investigating neurodegenerative diseases. J Neurosci Methods 1:108708. https://doi.org/10.1016/j.jneumeth.2020.108708CrossRef

21.

Marcelis L, Antoranz A, Delsupehe A-M et al (2020) In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy. Cancer Immunol Immunother 25:300–316. https://doi.org/10.1007/s00262-020-02575-yCrossRef

22.

Dall’Olio L, Bolognesi M, Borghesi S, Cattoretti G, Castellani G (2023) BRAQUE: Bayesian reduction for amplified quantization in UMAP embedding. Entropy. https://doi.org/10.3390/e25020354CrossRefPubMedPubMedCentral

23.

Boi G, Scalia CR, Gendusa R, Ronchi S, Cattoretti G (2016) Disaccharides protect antigens from drying-Induced damage in routinely processed tissue sections. J Histochem Cytochem 64(1):18–31. https://doi.org/10.1369/0022155415616162CrossRefPubMed

24.

Bolognesi MM, Bosisio FM, Cattoretti G (2020) Unidentified variables may account for variability in multiplexing results. J Histochem Cytochem 68(5):351–353. https://doi.org/10.1369/0022155420911050CrossRefPubMedPubMedCentral

25.

Mascadri F, Bolognesi MM, Pilla D, Cattoretti G (2021) Rejuvenated vintage tissue sections highlight individual antigen fate during processing and long-term storage. J Histochem Cytochem 69(10):659–667. https://doi.org/10.1369/00221554211047287CrossRefPubMedPubMedCentral

Title: Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN
Authors: Maddalena M. Bolognesi
Asier Antoranz
Francesca Maria Bosisio
Giorgio Cattoretti
Publication date: 01-12-2023
Publisher: BioMed Central
Published in: Acta Neuropathologica Communications / Issue 1/2023
Electronic ISSN: 2051-5960
DOI: https://doi.org/10.1186/s40478-023-01585-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Quantitative multiplex immunohistochemistry with colorimetric staining (QUIVER) may still benefit from MILAN

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 1/2023

A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons

Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion

Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain

Clinicopathological and molecular characterization of a case classified by DNA‑methylation profiling as “CNS embryonal tumor with BRD4–LEUTX fusion”

The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain

Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease