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Published in: Journal of Gastrointestinal Surgery 2/2009

01-02-2009 | review article

Quantitative Assessment of Hepatic Function and its Relevance to the Liver Surgeon

Authors: G. Morris-Stiff, D. Gomez, R. Prasad

Published in: Journal of Gastrointestinal Surgery | Issue 2/2009

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Abstract

Background

Standard evaluation of patients undergoing hepatic surgery has been through radiological and quantitative determination of liver function. As more complex and extensive surgery is now being performed, often in the presence of cirrhosis/fibrosis or following administration of chemotherapy, it is questioned whether additional assessment may be required prior to embarking on such surgery. The aim of this review was to determine the current knowledge base in relation to the performance of quantitative assessment of hepatic function both pre- and post-operatively in patients undergoing hepatic resectional surgery and liver transplantation.

Methods

An electronic search was performed of the medical literature using the MEDLINE database to identify relevant articles with cross-referencing of all identified papers to ensure full literature capture.

Results and Conclusions

The review has identified a number of different methods of dynamically assessing hepatic function, the most frequently performed being through the use of indocyanine green clearance. With the recent and further anticipated developments in hepatic resectional surgery, it is likely that quantitative assessment will become more widely practiced in order to reduce post-operative hepatic failure and improve outcome.
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Metadata
Title
Quantitative Assessment of Hepatic Function and its Relevance to the Liver Surgeon
Authors
G. Morris-Stiff
D. Gomez
R. Prasad
Publication date
01-02-2009
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 2/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-008-0564-1

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