Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2015

Open Access 01-12-2015 | Research

Quality of life and its association with direct medical costs for COPD in urban China

Authors: Minmin Wu, Qi Zhao, Yue Chen, Chaowei Fu, Biao Xu

Published in: Health and Quality of Life Outcomes | Issue 1/2015

Login to get access

Abstract

Background

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide. Few studies have focused on the quality of life (QoL) associated medical costs for COPD in China.

Methods

A cross-sectional survey of 678 COPD patients was conducted in four major cities (Beijing, Shanghai, Guangzhou and Chengdu), China, in 2011. Data on socio-demographic information, health conditions and medical costs were collected through a face-to-face interview combined with medical record searching. The EuroQol (EQ-5D) health questionnaire was applied to assess the QoL of COPD patients.

Results

Among 678 patients with COPD, nearly 40% had difficulties in mobility, usual activities and pain/discomfort, one third had various degrees of anxiety/depression, and one fifth had difficulties in self-care. The COPD patients had a median utility score of 0.768 and a median visual analog scale score of 70. The degree of difficulties in any dimensions significantly increased, and utility and health scores decreased with severity of the disease. Age, gender and disease severity were significantly associated with the quality of life after taking other covariates into consideration. Poorer QoL was a significant indicator of higher direct medical costs for COPD patients.

Conclusion

Impaired quality of life was significantly linked to increased medical costs for COPD patients and could be an important measure for policy- and decision-making in COPD care.
Literature
1.
2.
Decramer M, Sibille Y, Bush A, Carlsen K-H, Rabe KF, Clancye L, et al. The European Union conference on chronic respiratory disease: purpose and conclusions. Eur Respir J. 2011;37(4):738–42.CrossRefPubMed
3.
Zhong N, Wang C, Yao W, Chen P, Kang J, Huang S, et al. Prevalence of Chronic Obstructive Pulmonary Disease in China: A Large, Population-based Survey. Am J Respir Crit Care Med. 2007;176(8):753–60.CrossRefPubMed
4.
Guarascio AJ, Ray SM, Finch CK, Self TH. The clinical and economic burden of chronic obstructive pulmonary disease in the USA. Clinicoecon Outcomes Res. 2013;5:235–45.PubMedCentralPubMed
5.
Haave E, Hyland ME, Skumlien S. The relation between measures of health status and quality of life in COPD. Chron Respir Dis. 2006;3:195–9.CrossRefPubMed
6.
Weinstein MC, Siegel JE, Gold MR, Kamlet MS. Recommendations of the panel on cost-effectiveness in health and medicine. JAMA. 1996;276:1253–8.CrossRefPubMed
7.
Ramli A, Leonard J, Harun R. Preliminary evidence on the Feldenkrais Method as an alternative therapy for patients with chronic obstructive pulmonary disease. Focus on Alternative & Complementary Therapies an Evidence-Based Approach. 2013;18(3):126–32.CrossRef
8.
Blankenburg T, Guettel A, Busch C, Schuette W. Six-minute walk distance and dyspnoea scores to assess the course of COPD exacerbation in elderly patients. Clinical Respiratory Journal. 2013;7(3):261–7.CrossRefPubMed
9.
Shino Michael Y, Lynch JP, Saggar R, Abtin F, Belperio JA, Saggar R. Pulmonary Hypertension Complicating Interstitial Lung Disease and COPD. Seminars in Respiratory & Critical Care Medicine. 2013;34(5):600–19.CrossRef
10.
Yorgancioglu A, Havlucu Y, Celik P, Dinc G, Saka A. Relation between quality of life and morbidity and mortality in COPD patients: Two-year follow-up study. COPD. 2010;7(4):248–53.CrossRefPubMed
11.
Pasquale MK, Sun SX, Song F, Hartnett HJ, Stemkowski SA. Impact of exacerbations on health care cost and resource utilization in chronic obstructive pulmonary diseasepatients with chronic bronchitis from a predominantly Medicare population. Int J Chron Obstruct Pulmon Dis. 2012;7:757–64.CrossRefPubMedCentralPubMed
12.
Punekar YS, Shukla A, Müllerova H. COPD management costs according to the frequency of COPD exacerbations in UK primary care. Int J Chron Obstruct Pulmon Dis. 2014;9:65–73.CrossRefPubMedCentralPubMed
13.
Thayer RE, Newman JR, McClain TM. Self-regulation of mood: strategies for changing a bad mood, raising energy, and reducing tension. J Pers Soc Psychol. 1994;67(5):910–25.CrossRefPubMed
14.
Lemmens KM, Nieboer AP, Huijsman R. Designing patient related interventions in COPD care: empirical test of a theoretical model. Patient Educ Couns. 2008;72:223–31.CrossRefPubMed
15.
Ninot G, Moullec G, Picot MC, Jaussent A, Hayot M, Desplan M, et al. Cost-saving effect of supervised exercise associated to COPD self-management education program. Respir Med. 2011;105:377–85.CrossRefPubMed
16.
Collaboration P-T. Optimizing chronic disease management mega-analysis: economic evaluation. Ont Health Technol Assess Ser. 2013;13:1–148.
17.
Susan G, Kathleen M. Fox and for the SHIELD Study Group: Change in health status (EQ-5D) over 5 years among individuals with and without type 2 diabetes mellitus in the SHIELD longitudinal study. Health and Qulity of Life Outcoms. 2012;10:99–106.CrossRef
18.
COPD Group of Chinese Thoracic Society. The guideline for the diagnosis and treatment of COPD (updated in 2007). Ji Xu Yi Xue Jiao Yu, 2009;21(2):21-42.
19.
Macran S, Weatherly H, Kind P. Measuring population health: a comparison of three generic health status measures. Med Care. 2003;41:218–31.PubMed
20.
Gold MR, Siegel JE, Russell LB, Weinstein MC. Cost-effectiveness in health and medicine. New York: Oxford University Press; 1996.
21.
22.
Suchiya A, Ikeda S, Ikegami N, Nishimura S, Sakai I, Fukuda T, et al. Estimating an EQ-5D population value set: the case of Japan. Health Econ. 2002;11(4):341–53.CrossRef
23.
Pickard AS, Wilke CT, Lin HW, Lloyd A. Health utilities using the EQ-5D in studies of cancer. Pharmacoeconomics. 2007;25(5):365–84.CrossRefPubMed
24.
Sullivan PW, Lawrence WF, Ghushchyan V. A national catalog of preference-based scores for chronic conditions in the United States. Med Care. 2005;43(7):736–49.CrossRefPubMed
25.
Osman LM, Ayres JG, Garden C, Reglitz K, Lyon J, Douglas JG. Home warmth and health status of COPD patients. Eur J Public Health. 2008;18(4):399–405.CrossRefPubMed
26.
Ståhl E1, Lindberg A, Jansson SA, Rönmark E, Svensson K, Andersson F, et al. Health-related quality of life is related to COPD disease severity. Health Qual Life Outcomes. 2005;3:56.CrossRefPubMedCentralPubMed
27.
Pickard AS, Yang Y, Lee TA. Comparison of health-related quality of life measures in chronic obstructive pulmonary disease. Health Qual Life Outcomes. 2011;9:26.CrossRefPubMedCentralPubMed
28.
Rutten-van Mölken MP, Oostenbrink JB, Tashkin DP, Burkhart D, Monz BU. Does quality of life of COPD patients as measured by the generic EuroQol five-dimension questionnaire differentiate between COPD severity stages? Chest. 2006;130(4):1117–28.CrossRefPubMed
29.
Kim SH, Oh YM, Jo MW. Health-related quality of life in chronic obstructive pulmonary disease patients in Korea. Health Qual Life Outcomes. 2014;12:57.CrossRefPubMedCentralPubMed
30.
Stavem K. Reliability, validity and responsiveness of two multiattribute utility measures in patients with chronic obstructive pulmonary disease. Qual Life Res. 1999;8(1–2):45–54.CrossRefPubMed
31.
Tengs TO, Wallace A. One thousand health-related quality-of-life estimates. Med Care. 2000;38(6):583–637.CrossRefPubMed
32.
Pickard AS, Wilke C, Jung E, Patel S, Stavem K, Lee TA. Use of a preference-based measure of health (EQ-5D) in COPD and asthma. Respir Med. 2008;102(4):519–36.CrossRefPubMed
Metadata
Title
Quality of life and its association with direct medical costs for COPD in urban China
Authors
Minmin Wu
Qi Zhao
Yue Chen
Chaowei Fu
Biao Xu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2015
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-015-0241-5

Other articles of this Issue 1/2015

Health and Quality of Life Outcomes 1/2015 Go to the issue

Research

Preoperative and early postoperative quality of life after major surgery - a prospective observational study

Research

The negative impact of spasticity on the health-related quality of life of stroke survivors: a longitudinal cohort study

Research

Psychometric evaluation of health related quality of life among rural-to-urban migrants in China

Research Article

Modelling of diabetes knowledge, attitudes, self-management, and quality of life: a cross-sectional study with an Australian sample

Research Article

Health related quality of life in patients with actinic keratosis – an observational study of patients treated in dermatology specialist care in Denmark

Research

Translation, cross-cultural adaptation and psychometric evaluation of yoruba version of the short-form 36 health survey