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Open Access 01-05-2018

Quality of life after robot-assisted transmediastinal radical surgery for esophageal cancer

Authors: Shuntaro Yoshimura, Kazuhiko Mori, Yukinori Yamagata, Susumu Aikou, Koichi Yagi, Masato Nishida, Hiroharu Yamashita, Sachiyo Nomura, Yasuyuki Seto

Published in: Surgical Endoscopy | Issue 5/2018

Abstract

Background

The aim of this retrospective study was to assess postoperative quality of life (QOL) after robot-assisted radical transmediastinal esophagectomy, defined as a nontransthoracic esophagectomy with radical mediastinal lymphadenectomy combining a robotic transhiatal approach and a video-assisted cervical approach. The results were compared to those of transthoracic esophagectomy.

Methods

In this study, all consecutive patients who underwent robot-assisted radical transmediastinal esophagectomy or transthoracic esophagectomy for esophageal cancer at University of Tokyo between January 2010 and December 2014 were included. The European Organization for Research and Treatment of Cancer (EORTC)’s quality of life questionnaires QLQ-C30 and QLQ-OES18 were sent to all patients that were still living, had no recurrence or other malignancy, and had not undergone a reoperation because of complications after esophagectomy.

Results

We were able to survey 63 (98.4%) of 64 eligible patients. We assessed and compared the QOL scores of both groups of patients. Compared to transthoracic esophagectomy, transmediastinal esophagectomy was associated with better QOL. Global health status and the physical, role, and cognitive function scale scores were significantly superior in the transmediastinal esophagectomy group (P = 0.004, < 0.0001, 0.007, 0.002, respectively). Fatigue, nausea and vomiting, pain, appetite loss, reflux, and taste scores were significant lower (superior) in the transmediastinal esophagectomy group (P = 0.003, 0.032, 0.025, 0.018, 0.001, 0.041, respectively).

Conclusions

This study indicates that robot-assisted radical transmediastinal esophagectomy is associated with better postoperative QOL compared to transthoracic esophagectomy. A larger study and prospective analyses are needed to confirm the current results.

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Title: Quality of life after robot-assisted transmediastinal radical surgery for esophageal cancer
Authors: Shuntaro Yoshimura
Kazuhiko Mori
Yukinori Yamagata
Susumu Aikou
Koichi Yagi
Masato Nishida
Hiroharu Yamashita
Sachiyo Nomura
Yasuyuki Seto
Publication date: 01-05-2018
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 5/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-017-5918-x

At a glance: The STEP trials

Springer Medicine

Quality of life after robot-assisted transmediastinal radical surgery for esophageal cancer

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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