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Published in: Health and Quality of Life Outcomes 1/2005

Open Access 01-12-2005 | Research

Quality of life after acute myocardial infarction: A comparison of diabetic versus non-diabetic acute myocardial infarction patients in Quebec acute care hospitals

Authors: Ewurabena Simpson, Louise Pilote

Published in: Health and Quality of Life Outcomes | Issue 1/2005

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Abstract

Background

Previous studies have evaluated the individual effects of acute myocardial infarction (AMI) and diabetes mellitus on health-related quality of life outcomes (QOL). Due to the rising incidence of these comorbid conditions, it is important to examine the synergistic impact of diabetes mellitus and AMI on QOL.

Methods

In this study, we assessed using several previously validated questionnaires the QOL and functional status of 96 diabetic patients and 491 non-diabetic patients admitted to Quebec hospital sites with AMI between 1997 and 1998. We also conducted multivariate analyses to ascertain whether diabetes mellitus was an independent determinant of SF-36 physical functioning (PCS) and mental health (MCS) component score QOL outcomes after AMI.

Results

Both patient groups had similar baseline clinical characteristics, but diabetic patients had slightly higher rates of cardiac risk factors compared to non-diabetics. Overall, QOL measures were similar between both patient groups at baseline, but diabetic patients reported poorer functional status than non-diabetic patients. Over the study period, there were significant differences between the QOL and functional status of diabetic and non-diabetic populations. By one year, diabetic patients reported poorer QOL outcomes than non-diabetic patients. However, diabetic patients showed greater improvements in their functional status, but were less likely to return to work compared to non-diabetic patients. In contrast with these findings, our multivariate analyses showed that diabetes mellitus was not an independent determinant of QOL and functional status.

Conclusion

Our study findings suggest that diabetes mellitus is not an independent determinant of QOL after AMI.
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Literature
1.
go back to reference Westin L, Carlson R, Israelsson B, Willenheimer R CC, McNeil TF: Quality of life in patients with ischaemic heart disease: A prospective controlled study. J Intern Med 1997, 242: 239–247. 10.1046/j.1365-2796.1997.00203.xPubMedCrossRef Westin L, Carlson R, Israelsson B, Willenheimer R CC, McNeil TF: Quality of life in patients with ischaemic heart disease: A prospective controlled study. J Intern Med 1997, 242: 239–247. 10.1046/j.1365-2796.1997.00203.xPubMedCrossRef
2.
go back to reference Brown N, Melville M, Gray D, Young T, Munro J, Skene AM, Hampton JR: Quality of life four years after acute myocardial infarction: short form 36 scores compared with a normal population. Heart 1999, 81: 352–358.PubMedCentralPubMedCrossRef Brown N, Melville M, Gray D, Young T, Munro J, Skene AM, Hampton JR: Quality of life four years after acute myocardial infarction: short form 36 scores compared with a normal population. Heart 1999, 81: 352–358.PubMedCentralPubMedCrossRef
3.
go back to reference Wiklund I, Herlitz J, Bengston A, Hjalmarson A: Long-term follow-up of health-related quality of life in patients with suspected acute myocardial infarction when the diagnosis was not confirmed. Scand J Prim Health Care 1991, 9: 47–52.PubMedCrossRef Wiklund I, Herlitz J, Bengston A, Hjalmarson A: Long-term follow-up of health-related quality of life in patients with suspected acute myocardial infarction when the diagnosis was not confirmed. Scand J Prim Health Care 1991, 9: 47–52.PubMedCrossRef
4.
go back to reference Bergner L, Hallstrom AP, Bergner M, Eisenberg MS, Cobb LA: Health status of survivors of cardiac arrest and of myocardial infarction. Am J Pub Health 1985, 75: 1321–1323.CrossRef Bergner L, Hallstrom AP, Bergner M, Eisenberg MS, Cobb LA: Health status of survivors of cardiac arrest and of myocardial infarction. Am J Pub Health 1985, 75: 1321–1323.CrossRef
5.
go back to reference Agarwal M, Dalal AK, Agarwal DK, Agarwal RK: Positive life orientation and recovery from myocardial infarction. Soc Sci Med 1995, 40: 125–130. 10.1016/0277-9536(94)E0058-ZPubMedCrossRef Agarwal M, Dalal AK, Agarwal DK, Agarwal RK: Positive life orientation and recovery from myocardial infarction. Soc Sci Med 1995, 40: 125–130. 10.1016/0277-9536(94)E0058-ZPubMedCrossRef
6.
go back to reference Dugmore LD, Tipson RJ, Phillips MH, Flint EJ, Stentiford NH, Bone MF, Littler WA: Changes in cardiorespiratory fitness, psychological wellbeing, quality of life, and vocational status following a 12-month cardiac exercise rehabilitation programme. Heart 1999, 81: 359–366.PubMedCentralPubMedCrossRef Dugmore LD, Tipson RJ, Phillips MH, Flint EJ, Stentiford NH, Bone MF, Littler WA: Changes in cardiorespiratory fitness, psychological wellbeing, quality of life, and vocational status following a 12-month cardiac exercise rehabilitation programme. Heart 1999, 81: 359–366.PubMedCentralPubMedCrossRef
7.
go back to reference Jones DA, West RR: Psychological rehabilitation after myocardial infarction: Multicentre randomised controlled trial. Br Med J 1996, 313: 1517–1521.CrossRef Jones DA, West RR: Psychological rehabilitation after myocardial infarction: Multicentre randomised controlled trial. Br Med J 1996, 313: 1517–1521.CrossRef
8.
go back to reference Oldridge N, Guyatt G, Jones N, Crowe J, Singer J, Feeny D, McKelvie R, Runions J, Streiner D, Torrance G: Effects on quality of life with comprehensive rehabilitation after acute myocardial infarction. Am J Cardiol 1991, 67: 1084–1089. 10.1016/0002-9149(91)90870-QPubMedCrossRef Oldridge N, Guyatt G, Jones N, Crowe J, Singer J, Feeny D, McKelvie R, Runions J, Streiner D, Torrance G: Effects on quality of life with comprehensive rehabilitation after acute myocardial infarction. Am J Cardiol 1991, 67: 1084–1089. 10.1016/0002-9149(91)90870-QPubMedCrossRef
9.
go back to reference Taylor R, Kirby B, Burdon D, Caves R: The assessment of recovery in patients after myocardial infarction using three generic quality-of-life measures. J Cardiopulm Rehab 1998, 18: 139–144. 10.1097/00008483-199803000-00007CrossRef Taylor R, Kirby B, Burdon D, Caves R: The assessment of recovery in patients after myocardial infarction using three generic quality-of-life measures. J Cardiopulm Rehab 1998, 18: 139–144. 10.1097/00008483-199803000-00007CrossRef
10.
go back to reference Glasziou PP, Bromwich S, Simes RJ: Quality of life six months after myocardial infarction treated with thrombolytic therapy. Med J Aust 1994, 161: 532–536.PubMed Glasziou PP, Bromwich S, Simes RJ: Quality of life six months after myocardial infarction treated with thrombolytic therapy. Med J Aust 1994, 161: 532–536.PubMed
11.
go back to reference Stewart AL, Greenfield S, Hays RD, Wells K, Rogers WH, Berry SD, McGlynn EA, Ware JEJ: Functional status and well-being of patients with chronic conditions: results from the Medical Outcomes Study. JAMA 1989, 262: 907–913. 10.1001/jama.262.7.907PubMedCrossRef Stewart AL, Greenfield S, Hays RD, Wells K, Rogers WH, Berry SD, McGlynn EA, Ware JEJ: Functional status and well-being of patients with chronic conditions: results from the Medical Outcomes Study. JAMA 1989, 262: 907–913. 10.1001/jama.262.7.907PubMedCrossRef
12.
go back to reference Mark DB, Naylor CD, Hlatky MA, Califf R, Topol EJ, Granger CB, Knight JD, Nelson CL, Lee KL, Clapp-Channing N, Pryor DB, Sutherland W, Pilote L, Armstrong PW: Use of medical resource and quality of life after myocardial infarction in Canada and the United States. N Engl J Med 1994, 331: 1130–1135. 10.1056/NEJM199410273311706PubMedCrossRef Mark DB, Naylor CD, Hlatky MA, Califf R, Topol EJ, Granger CB, Knight JD, Nelson CL, Lee KL, Clapp-Channing N, Pryor DB, Sutherland W, Pilote L, Armstrong PW: Use of medical resource and quality of life after myocardial infarction in Canada and the United States. N Engl J Med 1994, 331: 1130–1135. 10.1056/NEJM199410273311706PubMedCrossRef
13.
go back to reference Bourdel-Marchasson I, Dubroca B, Manciet G, Decamps A, Emeriau JP, Dartigues JF: Prevalence of diabetes and effect on quality of life in older French living in the community: The PAQUID Epidemiological Study. J Am Geriatr Soc 1997, 45: 295–301.PubMedCrossRef Bourdel-Marchasson I, Dubroca B, Manciet G, Decamps A, Emeriau JP, Dartigues JF: Prevalence of diabetes and effect on quality of life in older French living in the community: The PAQUID Epidemiological Study. J Am Geriatr Soc 1997, 45: 295–301.PubMedCrossRef
14.
go back to reference Klein BEK, Klein R, Moss SE: Self-rated health and diabetes of long duration: The Wisconsin epidemiologic study of diabetic retinopathy. Diabetes Care 1998, 21: 236–240.PubMedCrossRef Klein BEK, Klein R, Moss SE: Self-rated health and diabetes of long duration: The Wisconsin epidemiologic study of diabetic retinopathy. Diabetes Care 1998, 21: 236–240.PubMedCrossRef
15.
go back to reference Testa MA, Simonson DC: Health economic benefits and quality of life during improved glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled, double-blind trial. JAMA 1998, 280: 1490–1496. 10.1001/jama.280.17.1490PubMedCrossRef Testa MA, Simonson DC: Health economic benefits and quality of life during improved glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled, double-blind trial. JAMA 1998, 280: 1490–1496. 10.1001/jama.280.17.1490PubMedCrossRef
16.
go back to reference Petterson T, Lee P, Hollis S, Young B, Newton P, Dorman T: Well-being and treatment satisfaction in older people with diabetes. Diabetes Care 1998, 21: 930–935.PubMedCrossRef Petterson T, Lee P, Hollis S, Young B, Newton P, Dorman T: Well-being and treatment satisfaction in older people with diabetes. Diabetes Care 1998, 21: 930–935.PubMedCrossRef
17.
go back to reference Glasgow RE, Ruggiero L, Eakin EG, Dryfoos J, Chobanian L: Quality of life and associated characteristics in a large national sample of adults with diabetes. Diabetes Care 1997, 20: 562–567.PubMedCrossRef Glasgow RE, Ruggiero L, Eakin EG, Dryfoos J, Chobanian L: Quality of life and associated characteristics in a large national sample of adults with diabetes. Diabetes Care 1997, 20: 562–567.PubMedCrossRef
18.
go back to reference Rose M, Burkert U, Scholler G, Schirop T, Danzer G, Klapp BF: Determinants of the quality of life of patients with diabetes under intensified insulin therapy. Diabetes Care 1998, 21: 1876–1885.PubMedCrossRef Rose M, Burkert U, Scholler G, Schirop T, Danzer G, Klapp BF: Determinants of the quality of life of patients with diabetes under intensified insulin therapy. Diabetes Care 1998, 21: 1876–1885.PubMedCrossRef
19.
go back to reference Pilote L, Lauzon C, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F, Lévesque C, Pouliot J, Joseph L, Eisenberg MJ: Quality of life after acute myocardial infarction among patients treated at sites with and without on-site availability of angiography. Arch Intern Med 2002, 162: 553–559. 10.1001/archinte.162.5.553PubMedCrossRef Pilote L, Lauzon C, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F, Lévesque C, Pouliot J, Joseph L, Eisenberg MJ: Quality of life after acute myocardial infarction among patients treated at sites with and without on-site availability of angiography. Arch Intern Med 2002, 162: 553–559. 10.1001/archinte.162.5.553PubMedCrossRef
20.
go back to reference Ware JE, Snow KK, Kosinski M, Gandek B: . In SF-36 Health Survey & Interpretation Guide. Boston, MA, The Health Institute, New England Medical Center; 1993. Ware JE, Snow KK, Kosinski M, Gandek B: . In SF-36 Health Survey & Interpretation Guide. Boston, MA, The Health Institute, New England Medical Center; 1993.
21.
go back to reference Furlong W, Feeny D, Torrance GW, Barr R, Horsman J CHEP A working paper series. In Guide to design and development of health-state utility instrumentation. Hamilton, McMaster University; 1990. Furlong W, Feeny D, Torrance GW, Barr R, Horsman J CHEP A working paper series. In Guide to design and development of health-state utility instrumentation. Hamilton, McMaster University; 1990.
22.
go back to reference Torrance GW: Measurement of health state utilities for economic appraisal: a review. J Health Econ 1986, 5: 1–30. 10.1016/0167-6296(86)90020-2PubMedCrossRef Torrance GW: Measurement of health state utilities for economic appraisal: a review. J Health Econ 1986, 5: 1–30. 10.1016/0167-6296(86)90020-2PubMedCrossRef
23.
go back to reference Hurts NP, Jobanputra P, Hunter M, Lamber M, Lochhead A, Brown H: Validity of EuroQol - a generic health status instrument in patients with rheumatoid arthritis. Br J Rheumatol 1994, 33: 655–662.CrossRef Hurts NP, Jobanputra P, Hunter M, Lamber M, Lochhead A, Brown H: Validity of EuroQol - a generic health status instrument in patients with rheumatoid arthritis. Br J Rheumatol 1994, 33: 655–662.CrossRef
24.
go back to reference Statistics NCH: Health, United States, 1991. Hyattsville, Public Health Service, CDC; 1992. Statistics NCH: Health, United States, 1991. Hyattsville, Public Health Service, CDC; 1992.
25.
go back to reference Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Callif RM, Cobb FR, Pryor DB: A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol 1989, 64: 651–654. 10.1016/0002-9149(89)90496-7PubMedCrossRef Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Callif RM, Cobb FR, Pryor DB: A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol 1989, 64: 651–654. 10.1016/0002-9149(89)90496-7PubMedCrossRef
26.
go back to reference Katz S, Downs TD, Cash HR, Grotz RC: Progress in the development of the index of ADL. Gerontologist 1970, 10: 20–30.PubMedCrossRef Katz S, Downs TD, Cash HR, Grotz RC: Progress in the development of the index of ADL. Gerontologist 1970, 10: 20–30.PubMedCrossRef
27.
go back to reference investigators TBARI: Protocol for the Bypass Angiography Revascularization Investigation. Circulation 1988, 84: V1-V27. investigators TBARI: Protocol for the Bypass Angiography Revascularization Investigation. Circulation 1988, 84: V1-V27.
28.
go back to reference Kleinbaum DG, Kupper LL, Muller KE: Applied regression analysis and other multivariable methods. Boston, MA, PWS-Kent Publishing Company; 1988. Kleinbaum DG, Kupper LL, Muller KE: Applied regression analysis and other multivariable methods. Boston, MA, PWS-Kent Publishing Company; 1988.
29.
go back to reference Goldberg RB, Mellies MJ, Sacks FM, Moyé LA, Howard BV, Howard WJ, Davis BR, Cole TG, Pfeffer MA, Braunwald E, Investigators CARE: Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels. Circulation 1998, 98: 2513–2519.PubMedCrossRef Goldberg RB, Mellies MJ, Sacks FM, Moyé LA, Howard BV, Howard WJ, Davis BR, Cole TG, Pfeffer MA, Braunwald E, Investigators CARE: Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels. Circulation 1998, 98: 2513–2519.PubMedCrossRef
Metadata
Title
Quality of life after acute myocardial infarction: A comparison of diabetic versus non-diabetic acute myocardial infarction patients in Quebec acute care hospitals
Authors
Ewurabena Simpson
Louise Pilote
Publication date
01-12-2005
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2005
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-3-80

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