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Supportive Care in Cancer
Published in: Supportive Care in Cancer 4/2019

01-04-2019 | Original Article

Qigong intervention for breast cancer survivors with complaints of decreased cognitive function

Authors: Jamie S. Myers, Melissa Mitchell, Susan Krigel, Andreanna Steinhoff, Alyssa Boyce-White, Karla Van Goethem, Mary Valla, Junqiang Dai, Jianghua He, Wen Liu, Susan M Sereika, Catherine M Bender

Published in: Supportive Care in Cancer | Issue 4/2019

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Abstract

Purpose

The purpose of this pilot study was to evaluate the feasibility of an 8-week Qigong intervention to improve objectively and subjectively assessed cognitive function in breast cancer survivors who were 2 months to 8 years post completion of chemotherapy and radiation therapy.

Methods

A randomized, single-blind, three-arm intervention pilot was conducted to compare Qigong to gentle exercise and survivorship support. Feasibility was measured by recruitment, group session attendance, and adherence to home practice for the two exercise groups. Changes in self-report and objectively measured cognitive function were compared between the three groups from baseline (T1) to completion of the intervention (T2) and 4 weeks post intervention (T3).

Results

Fifty participants consented (83% of desired sample) with an overall attrition rate of 28%. Attrition was highest for the gentle exercise group (50%). Group attendance adherence ranged from 44 to 67%. The a priori established rate of 75% weekly attendance was not achieved, nor was the goal of 75% adherence to home practice for the two exercise groups (7 to 41%). Self-report of cognitive function improved most for the Qigong group (p = .01). Improvement was demonstrated for the Trail Making A (gentle exercise, p = .007) and F-A-S verbal fluency (support group, p = .02) tests. Qigong participants reported the most reduction of distress (p = .02).

Conclusions

The study results suggest that mindfulness-based exercise may be superior to gentle exercise alone or survivorship support for improving self-report of cognitive function and distress after treatment for breast cancer. The mindfulness component may enhance the positive impact of exercise on cognitive function.
Literature
1.
Carlson LE, Bultz BD (2003) Cancer, distress screening: needs, models and methods. J Psychosom Res 55:403–409CrossRefPubMed
2.
Hampson JP, Zick SM, Khabir T, Wright BD, Harris RE (2015) Altered resting brain connectivity in persistent cancer related fatigue. Neuroimage Clin 8:305–313CrossRefPubMedPubMedCentral
3.
4.
Von AD, Jansen C, Allen DH (2014) Evidence-based interventions for cancer- and treatment-related cognitive impairment. Clin J Oncol Nurs 18:17–25CrossRef
5.
Asher A, Myers JS (2015) The effect of cancer treatment on cognitive function. Clin Adv Hematol Oncol 13(7):441–450PubMed
6.
Myers JS (2015) Complementary and integrative interventions for cancer-related cognitive changes. Asia Pac J Oncol Nurs
7.
8.
Baumann FT, Drosselmeyer N, Leskaroski A, Knicker A, Krakowski-Roosen H, Zopf EM, Bloch W (2011) 12-week resistance training with breast cancer patients during chemotherapy: effects on cognitive abilities. Breast Care 6:142–143CrossRef
9.
Crowgey T, Peters KB, Hornsby WE, Lane A, McSherry F, Herndon JE, West MJ, Williams CL, Jones LW (2014) Relationship between exercise behavior, cardiorespiratory fitness, and cognitive function in early breast cancer patients treated with doxorubicin-containing chemotherapy: a pilot study. Appl Physiol Nutr Metab 39:724–729CrossRefPubMed
10.
11.
Knobf MT, Thompson A, Fennie K, Erdos D (2013) The effect of a community-based exercise intervention on symptoms and quality of life. Cancer Nurs 37:E43–E50CrossRef
12.
Milbury K, Chaol A, Biegler KA, Wangyal T, Spelmen A, Meyers C, Arun B, Palmer JL, Taylor JA, Cohen L (2013) Tibetan sound meditation for cognitive dysfunction: results of a randomized controlled pilot trial. Psychooncology 22:2354–2363CrossRefPubMedPubMedCentral
13.
14.
Reid-Arndt AA, Matsuda S, Cox CR (2012) Tai chi effects on neuropsychological, emotional, and physical functioning following cancer treatment: a pilot study. Complement Ther Clin Pract 18:26–30CrossRefPubMed
15.
Sprod LK, Mohile SG, Demark-Wahnefried W, Janelsins MC, Peppone LJ, Morrow GR, Lord R, Gross H, Mustian KM (2012) Exercise and cancer treatment symptoms in 408 newly diagnosed older cancer patients. J Geriatr Oncol 3:90–97CrossRefPubMedPubMedCentral
16.
Larkey LK, Roe DJ, Weihs KL, jahnke R, Lopez AM, Rogers CE, OH B, Guillen-Rodriguez (2015) Randomized controlled trial of qigong/tai chi easy on cancer-related fatigue in breast cancer survivors. Ann Behav Med 49:165–176CrossRefPubMedPubMedCentral
17.
Lindquist R, Wyman JF, Talley KM, Findorff MJ, Gross CR (2007) Design of control-group conditions in clinical trials of behavioral interventions. J Nurs Scholarsh 39:214–221CrossRefPubMed
18.
19.
Ahles TA, Saykin A (2002) Breast cancer chemotherapy-related cognitive dysfunction. Clin Breast Cancer 3(Suppl 3):S84–S90CrossRefPubMed
20.
Campo RA, Agarwal N, LaStayo PC, O'Connor K, Pappas L, Boucher KM, Gardner J, Smith S, Light KC, Kinney AY (2014) Levels of fatigue and distress in senior prostate cancer survivors enrolled in a 12-week randomized controlled trial of Qigong. J Cancer Surviv 8:60–69CrossRefPubMed
21.
22.
Oh B, Butow P, Mullan B, Clarke S (2008) Medical Qigong for cancer patients: pilot study of impact on quality of life, side effects of treatment and inflammation. Am J Chin Med 36:459–472CrossRefPubMed
23.
24.
Liu W, Schaffer L, Herrs N, Choller C, Taylor S (2015) Improved sleep after Qigong exercise in breast cancer survivors, a pilot study. Asia Pac J Oncol Nurs submitted
25.
Sanford SD, Beaumont JL, Butt Z, Sweet J, Cella D, Wagner L (2014) Prospective longitudinal evaluation of a symptom cluster in breast cancer. J Pain Symptom Manag 47:721–730CrossRef
26.
27.
Cleeland CS, Mendoza TR, Wang XS, Chou C, Harle MT, Morrissey M, Engstrom MC (2000) Assessing symptom distress in cancer patients: the M.D. Anderson symptom inventory. Cancer 89:1634–1646CrossRefPubMed
28.
Johnson-Kozlow M, Rock CL, Gilpin EA, Hollenbach KA, Pierce JP (2007) Validation of the WHI brief physical activity questionnaire among women diagnosed with breast cancer. Am J Health Behav 31:193–202CrossRefPubMed
29.
Lai J, Butt Z, Wagner L, Sweet J, Beaumont JL, Vardy J, Jacobsen PB, Jacobs SR, Shapiro CL, Cella D (2009) Evaluating the dimensionality of perceived cognitive function. J Pain Symptom Manag 37:982–995CrossRef
30.
31.
Wefel J, Vardy J, Ahles TA, Schagen SB (2011) International cognition and cancer task force recommendations to harmonise studies of cognitive function in patients with cancer. Lancet Oncol 12:703–708CrossRefPubMed
32.
Luo L, Luk G, Bialystok E (2010) Effect of language proficiency and executive control on verbal fluency performance in bilinguals. Cognition 114:29–41CrossRefPubMed
33.
Strauss E, Sherman EM, Spreen O (2006) A compendium of neuropsychological tests: Administration, norms, and commentary, vol 3rd edn. Oxford University Press, New York
Metadata
Title
Qigong intervention for breast cancer survivors with complaints of decreased cognitive function
Authors
Jamie S. Myers
Melissa Mitchell
Susan Krigel
Andreanna Steinhoff
Alyssa Boyce-White
Karla Van Goethem
Mary Valla
Junqiang Dai
Jianghua He
Wen Liu
Susan M Sereika
Catherine M Bender
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 4/2019
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-018-4430-8

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