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Open Access 01-11-2013 | Meeting abstract

PW02-039 - Long-term anakinra treatment in CAPS: a metaanalys

Authors: M Leinonen, B Hallén, M Aldén-Raboisson, H Olivecrona

Published in: Pediatric Rheumatology | Special Issue 1/2013

Excerpt

The common denominator in CAPS (FCAS, Muckle-Wells syndrome, NOMID/CINCA) is an uncontrolled IL-1β release. An often complete response after treatment with the IL-1 blocker anakinra (Kineret®) has been demonstrated in all three entities of CAPS [1‐3]. However, the overall documentation is limited due to the inherent difficulties in conducting randomized studies in the more severe forms of the disease, and the low prevalence of CAPS (1 in 1 000 000). The literature consists of uncontrolled, small clinical studies, and a large number of case reports. …

Hawkins PN: N Engl J Med. 2003, 348: 2583-2584.CrossRefPubMed

Hoffman HM: Lancet. 2004, 364: 1779-1785.PubMedCentralCrossRefPubMed

Goldbach-Mansky : N Engl J Med. 2006, 355: 581-592.PubMedCentralCrossRefPubMed

Lepore : J Pediatr. 157 (2): 310-315.

Title: PW02-039 - Long-term anakinra treatment in CAPS: a metaanalys
Authors: M Leinonen
B Hallén
M Aldén-Raboisson
H Olivecrona
Publication date: 01-11-2013
Publisher: BioMed Central
Published in: Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI: https://doi.org/10.1186/1546-0096-11-S1-A180

Keynote webinar | Spotlight on medication adherence

Springer Medicine

PW02-039 - Long-term anakinra treatment in CAPS: a metaanalys

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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