Skip to main content
Top

Open Access 03-05-2024 | Research

Pulsed electromagnetic fields (PEMF) as a valid tool in orthognathic surgery to reduce post-operative pain and swelling: a prospective study

Authors: Marco Friscia, Vincenzo Abbate, Gianluca Renato De Fazio, Lorenzo Sani, Raffaele Spinelli, Stefania Troise, Paola Bonavolontà, Umberto Committeri, Luigi Califano, Giovanni Dell’Aversana Orabona

Published in: Oral and Maxillofacial Surgery

Login to get access

Abstract

Purpose

PEMF (pulsed electromagnetic fields) founds application in several medical fields to accelerate bone wounds healing and to reduce inflammation. The aim of our study was to evaluate the effectiveness of PEMF in reducing postoperative swelling and pain in patients undergoing orthognathic surgery.

Methods

A prospective observational monocentric study was conducted on a sample of 30 patients undergone to orthognathic surgery in Maxillofacial Surgery Unit of University of Naples Federico II. The patients who followed these inclusion criteria were enrolled in the study: age ≥ 18 years, Class III malocclusion, Surgical procedure of Le Fort I osteotomy + Bilateral Sagittal Split Osteotomy (BSSO), Written informed consent. Patients were divided into two groups: Group SD) postoperative standard treatment with medical therapy and cryotherapy, Group SD + PEMF) postoperative standard therapy + PEMF. Each patient underwent a 3D facial scan, at one (1d) and four (4d) days after surgery to compare the swelling reduction. The pain score was assessed through VAS score and analgesics administration amount.

Results

In SD + PEMF group, the facial volume reduction between 1d and 4d scan was on average 56.2 ml (6.23%), while in SD group, it was 23.6 ml (2.63%). The difference between the two groups was 3.6% (p = 0.0168). VAS pain values were significantly higher in SD group compared to SD + PEMF group in the second day after surgery (P = 0.021) and in the total 4 days (P = 0.008).

Conclusions

Our data suggest that PEMF is valid tool to promote faster postoperative swelling and pain reduction in patients undergoing orthognathic surgery.
Literature
1.
go back to reference AlAsseri N, Swennen G (2018) Minimally invasive orthognathic surgery: a systematic review. Int J Oral Maxillofac Surg 47(10):1299–1310CrossRefPubMed AlAsseri N, Swennen G (2018) Minimally invasive orthognathic surgery: a systematic review. Int J Oral Maxillofac Surg 47(10):1299–1310CrossRefPubMed
2.
go back to reference de Lima VN, Lemos CAA, Faverani LP, Júnior Santiago JF, Pellizzer EP (2017) Effectiveness of Corticoid Administration in Orthognathic surgery for Edema and Neurosensorial Disturbance: a systematic literature review. J Oral Maxillofac Surg 75(7):1528e1–1528e8CrossRef de Lima VN, Lemos CAA, Faverani LP, Júnior Santiago JF, Pellizzer EP (2017) Effectiveness of Corticoid Administration in Orthognathic surgery for Edema and Neurosensorial Disturbance: a systematic literature review. J Oral Maxillofac Surg 75(7):1528e1–1528e8CrossRef
3.
go back to reference Friscia M, Seidita F, Committeri U et al (2022) Efficacy of Hilotherapy face mask in improving the trend of edema after orthognathic surgery: a 3D analysis of the face using a facial scan app for iPhone. Oral Maxillofac Surg 26(3):485–490CrossRefPubMed Friscia M, Seidita F, Committeri U et al (2022) Efficacy of Hilotherapy face mask in improving the trend of edema after orthognathic surgery: a 3D analysis of the face using a facial scan app for iPhone. Oral Maxillofac Surg 26(3):485–490CrossRefPubMed
4.
go back to reference Moro A, Gasparini G, Marianetti TM et al (2011) Hilotherm efficacy in controlling postoperative facial edema in patients treated for maxillomandibular malformations. J Craniofac Surg 22(6):2114–2117CrossRefPubMed Moro A, Gasparini G, Marianetti TM et al (2011) Hilotherm efficacy in controlling postoperative facial edema in patients treated for maxillomandibular malformations. J Craniofac Surg 22(6):2114–2117CrossRefPubMed
5.
go back to reference Glass GE, Waterhouse N, Shakib K (2016) Hilotherapy for the management of perioperative pain and swelling in facial surgery: a systematic review and meta-analysis. Br J Oral Maxillofac Surg 54(8):851–856CrossRefPubMed Glass GE, Waterhouse N, Shakib K (2016) Hilotherapy for the management of perioperative pain and swelling in facial surgery: a systematic review and meta-analysis. Br J Oral Maxillofac Surg 54(8):851–856CrossRefPubMed
6.
go back to reference Cadossi R, Massari L, Racine-Avila J, Aaron RK (2020) Pulsed Electromagnetic Field Stimulation of Bone Healing and Joint Preservation: Cellular mechanisms of skeletal response. J Am Acad Orthop Surg Glob Res Rev 4(5):e1900155PubMed Cadossi R, Massari L, Racine-Avila J, Aaron RK (2020) Pulsed Electromagnetic Field Stimulation of Bone Healing and Joint Preservation: Cellular mechanisms of skeletal response. J Am Acad Orthop Surg Glob Res Rev 4(5):e1900155PubMed
7.
go back to reference Yuan J, Xin F, Jiang W (2018) Underlying signaling pathways and therapeutic applications of Pulsed Electromagnetic fields in Bone Repair. Cell Physiol Biochem 46(4):1581–1594CrossRefPubMed Yuan J, Xin F, Jiang W (2018) Underlying signaling pathways and therapeutic applications of Pulsed Electromagnetic fields in Bone Repair. Cell Physiol Biochem 46(4):1581–1594CrossRefPubMed
8.
go back to reference Fontanesi G, Traina GC, Giancecchi F, Tartaglia I, Rotini R, Virgili B, Cadossi R, Ceccherelli G, Marino AA (1986) Slow healing fractures: can they be prevented? (results of electrical stimulation in fibular osteotomies in rats and in diaphyseal fractures of the tibia in humans). Ital J Orthop Traumatol 12(3):371–385PubMed Fontanesi G, Traina GC, Giancecchi F, Tartaglia I, Rotini R, Virgili B, Cadossi R, Ceccherelli G, Marino AA (1986) Slow healing fractures: can they be prevented? (results of electrical stimulation in fibular osteotomies in rats and in diaphyseal fractures of the tibia in humans). Ital J Orthop Traumatol 12(3):371–385PubMed
9.
go back to reference Faldini C, Cadossi M, Luciani D, Betti E, Chiarello E, Giannini S (2010) Electromagnetic bone growth stimulation in patients with femoral neck fractures treated with screws: prospective randomized double-blind study. Curr Orthop Pract 21(3):282–287CrossRef Faldini C, Cadossi M, Luciani D, Betti E, Chiarello E, Giannini S (2010) Electromagnetic bone growth stimulation in patients with femoral neck fractures treated with screws: prospective randomized double-blind study. Curr Orthop Pract 21(3):282–287CrossRef
10.
go back to reference Jing D, Zhai M, Tong S et al (2016) Pulsed electromagnetic fields promote osteogenesis and osseointegration of porous titanium implants in bone defect repair through a Wnt/β-catenin signaling-associated mechanism. Sci Rep 6:32045CrossRefPubMedPubMedCentral Jing D, Zhai M, Tong S et al (2016) Pulsed electromagnetic fields promote osteogenesis and osseointegration of porous titanium implants in bone defect repair through a Wnt/β-catenin signaling-associated mechanism. Sci Rep 6:32045CrossRefPubMedPubMedCentral
11.
go back to reference Vadalà M, Morales-Medina JC, Vallelunga A, Palmieri B, Laurino C, Iannitti T (2016) Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology. Cancer Med 5(11):3128–3139CrossRefPubMedPubMedCentral Vadalà M, Morales-Medina JC, Vallelunga A, Palmieri B, Laurino C, Iannitti T (2016) Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology. Cancer Med 5(11):3128–3139CrossRefPubMedPubMedCentral
12.
go back to reference Kinney BM (2005) Pulsed electromagnetic field therapy in plastic surgery. Aesthet Surg J 25(1):87–91CrossRefPubMed Kinney BM (2005) Pulsed electromagnetic field therapy in plastic surgery. Aesthet Surg J 25(1):87–91CrossRefPubMed
13.
go back to reference De Oliveira TC, Rocha SF, Ramos DG, Ramos CG, Carvalho MV, Ramos MG (2017) Effects of Multipolar Radiofrequency and Pulsed Electromagnetic Field Treatment for Face and Neck Rejuvenation. Dermatol Res Pract 2017:4146391CrossRefPubMedPubMedCentral De Oliveira TC, Rocha SF, Ramos DG, Ramos CG, Carvalho MV, Ramos MG (2017) Effects of Multipolar Radiofrequency and Pulsed Electromagnetic Field Treatment for Face and Neck Rejuvenation. Dermatol Res Pract 2017:4146391CrossRefPubMedPubMedCentral
14.
go back to reference Brun-Buisson C (2000) The epidemiology of systemic inflammatory response. Intensive Care Med 26:864–874CrossRef Brun-Buisson C (2000) The epidemiology of systemic inflammatory response. Intensive Care Med 26:864–874CrossRef
15.
go back to reference Ross CL, Zhou Y, McCall CE, Soker S, Criswell TL (2019) The Use of Pulsed Electromagnetic Field to modulate inflammation and improve tissue regeneration: a review. Bioelectricity 1(4):247–259CrossRefPubMedPubMedCentral Ross CL, Zhou Y, McCall CE, Soker S, Criswell TL (2019) The Use of Pulsed Electromagnetic Field to modulate inflammation and improve tissue regeneration: a review. Bioelectricity 1(4):247–259CrossRefPubMedPubMedCentral
16.
go back to reference Abdelrahim A, Hassanein HR, Dahaba M (2011) Effect of pulsed electromagnetic field on healing of mandibular fracture: a preliminary clinical study. J Oral Maxillofac Surg 69(6):1708–1717CrossRefPubMed Abdelrahim A, Hassanein HR, Dahaba M (2011) Effect of pulsed electromagnetic field on healing of mandibular fracture: a preliminary clinical study. J Oral Maxillofac Surg 69(6):1708–1717CrossRefPubMed
17.
go back to reference Ongaro A, Pellati A, Setti S et al (2015) Electromagnetic fields counteract IL-1β activity during chondrogenesis of bovine mesenchymal stem cells. J Tissue Eng Regen Med 9(12):E229–E238CrossRefPubMed Ongaro A, Pellati A, Setti S et al (2015) Electromagnetic fields counteract IL-1β activity during chondrogenesis of bovine mesenchymal stem cells. J Tissue Eng Regen Med 9(12):E229–E238CrossRefPubMed
18.
go back to reference Funk RH (2018) Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell. Am J Transl Res 10(5):1260–1272PubMedPubMedCentral Funk RH (2018) Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell. Am J Transl Res 10(5):1260–1272PubMedPubMedCentral
19.
go back to reference Tabakan I, Yuvacı AU, Taştekin B, Öcal I, Pelit A (2022) The healing effect of pulsed magnetic field on burn wounds. Burns 48(3):649–653CrossRefPubMed Tabakan I, Yuvacı AU, Taştekin B, Öcal I, Pelit A (2022) The healing effect of pulsed magnetic field on burn wounds. Burns 48(3):649–653CrossRefPubMed
20.
go back to reference Canè V, Botti P, Soana S (1993) Pulsed magnetic fields improve osteoblast activity during the repair of an experimental osseous defect. J Orthop Res 11(5):664–670CrossRefPubMed Canè V, Botti P, Soana S (1993) Pulsed magnetic fields improve osteoblast activity during the repair of an experimental osseous defect. J Orthop Res 11(5):664–670CrossRefPubMed
21.
go back to reference Midura RJ, Ibiwoye MO, Powell KA et al (2005) Pulsed electromagnetic field treatments enhance the healing of fibular osteotomies. J Orthop Res 23(5):1035–1046CrossRefPubMed Midura RJ, Ibiwoye MO, Powell KA et al (2005) Pulsed electromagnetic field treatments enhance the healing of fibular osteotomies. J Orthop Res 23(5):1035–1046CrossRefPubMed
22.
go back to reference van der Vlis M, Dentino KM, Vervloet B, Padwa BL (2014) Postoperative swelling after orthognathic surgery: a prospective volumetric analysis. J Oral Maxillofac Surg 72(11):2241–2247CrossRefPubMed van der Vlis M, Dentino KM, Vervloet B, Padwa BL (2014) Postoperative swelling after orthognathic surgery: a prospective volumetric analysis. J Oral Maxillofac Surg 72(11):2241–2247CrossRefPubMed
23.
go back to reference Smith TL, Wong-Gibbons D, Maultsby J (2004) Microcirculatory effects of pulsed electromagnetic fields. J Orthop Res 22(1):80–84CrossRefPubMed Smith TL, Wong-Gibbons D, Maultsby J (2004) Microcirculatory effects of pulsed electromagnetic fields. J Orthop Res 22(1):80–84CrossRefPubMed
24.
go back to reference Menini M, Bevilacqua M, Setti P, Tealdo T, Pesce P, Pera P (2016) Effects of pulsed electromagnetic fields on swelling and pain after implant surgery: a double-blind, randomized study. Int J Oral Maxillofac Surg 45(3):346–353CrossRefPubMed Menini M, Bevilacqua M, Setti P, Tealdo T, Pesce P, Pera P (2016) Effects of pulsed electromagnetic fields on swelling and pain after implant surgery: a double-blind, randomized study. Int J Oral Maxillofac Surg 45(3):346–353CrossRefPubMed
25.
go back to reference Jung JG, Park JH, Kim SC, Kang KH, Cho JH, Cho JW, Chang NY, Bay RC, Chae JM (2017) Effectiveness of pulsed electromagnetic field for pain caused by placement of initial orthodontic wire in female orthodontic patients: a preliminary single-blind randomized clinical trial. Am J Orthod Dentofac Orthop 152(5):582–591CrossRef Jung JG, Park JH, Kim SC, Kang KH, Cho JH, Cho JW, Chang NY, Bay RC, Chae JM (2017) Effectiveness of pulsed electromagnetic field for pain caused by placement of initial orthodontic wire in female orthodontic patients: a preliminary single-blind randomized clinical trial. Am J Orthod Dentofac Orthop 152(5):582–591CrossRef
Metadata
Title
Pulsed electromagnetic fields (PEMF) as a valid tool in orthognathic surgery to reduce post-operative pain and swelling: a prospective study
Authors
Marco Friscia
Vincenzo Abbate
Gianluca Renato De Fazio
Lorenzo Sani
Raffaele Spinelli
Stefania Troise
Paola Bonavolontà
Umberto Committeri
Luigi Califano
Giovanni Dell’Aversana Orabona
Publication date
03-05-2024
Publisher
Springer Berlin Heidelberg
Published in
Oral and Maxillofacial Surgery
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI
https://doi.org/10.1007/s10006-024-01256-9