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01-03-2003 | Original Paper

Pulmonary re-occurrence of post-transplant lymphoproliferative disease with hypogammaglobulinaemia

Authors: Matthias T. F. Wolf, Eva Mildenberger, Thomas Lennert, Ioannis Anagnostopoulos, Christina Zinn, Karl Paul, Rolf Keitzer, Hans Versmold

Published in: European Journal of Pediatrics | Issue 3/2003

Abstract

We report the case of a 12-year-old boy, who developed Epstein-Barr virus (EBV) associated post-transplant lymphoproliferative disease (PTLD) 7 years after renal transplantation. He responded well to the reduced immunosuppressive therapy and treatment with ganciclovir. Two years later he developed severe pneumonia and hypogammaglobulinaemia related to EBV infection exacerbation. An X-ray film revealed persistent pneumonia in the right lung. Lung biopsy showed a large, diffuse EBV-associated B-cell lymphoma. This constellation suggested re-occurrence of the primary PTLD. Conclusion: We present a case of recurring Epstein-Barr virus-associated post-transplant lymphoproliferative disease with a remarkably late onset in addition to hypogammaglobulinaemia.

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Title: Pulmonary re-occurrence of post-transplant lymphoproliferative disease with hypogammaglobulinaemia
Authors: Matthias T. F. Wolf
Eva Mildenberger
Thomas Lennert
Ioannis Anagnostopoulos
Christina Zinn
Karl Paul
Rolf Keitzer
Hans Versmold
Publication date: 01-03-2003
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Pediatrics / Issue 3/2003
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-002-1120-8

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Springer Medicine

Pulmonary re-occurrence of post-transplant lymphoproliferative disease with hypogammaglobulinaemia

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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