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Open Access 01-12-2018 | Research article

Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review

Authors: Issam Bennis, Vincent De Brouwere, Zakaria Belrhiti, Hamid Sahibi, Marleen Boelaert

Published in: BMC Public Health | Issue 1/2018

Abstract

Background

Cutaneous Leishmaniasis (CL) is a parasitic skin disease, linked to poverty, and belonging to the group of Neglected Tropical Diseases. Depending on the severity, the type of lesions or scars, and the context, CL can lead to self- and social stigma influencing the quality of life and psychological well-being of the patient. This dimension is, however, little documented for the most common, localized form of cutaneous leishmaniasis (LCL).

We aimed to describe the current knowledge on the psychological burden and the stigma related to LCL.

Methods

The population of interest for this scoping review are patients or their relatives with localized LCL or related scars.

We searched the electronic databases PubMed, Web of Knowledge, PsycINFO, POPLINE, Cochrane Library, Science Direct, Global Health, and LILACS, for articles written in Arabic, English, French, Dutch, Portuguese, or Spanish, and published until the end of August 2017.

Results

From 2485 initial records, 15 papers met our inclusion criteria. Dermatology life quality index was the most frequent used scale to assess LCL psychological impact in quantitative studies. Six qualitative studies used individual interviews and/or focus groups discussions to explore the psychological and/or the social burden of this disease. Quantitative assessments using standard scales as well as qualitative research asserts that LCL is a source of psychological suffering, stigmatization, and decreased quality of life (QoL).

Conclusion

Most studies showed that LCL has a significant negative effect on the QoL and mental health. However, the fact that the psychosocial burden generated by LCL is time-dependent makes it hard to measure. We recommend to develop a more specific and validated assessment scale to appreciate the full burden of this disease and enhance comparability of findings.

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Karimkhani C, Wanga V, Coffeng LE, Naghavi P, Dellavalle RP, Naghavi M. Global burden of cutaneous leishmaniasis: a cross-sectional analysis from the global burden of disease study 2013. Lancet Infect Dis. 2016;16:584–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26879176.

Balley F, Mondragon-Shem K, Hotez P, Ruiz-Postigo JA, Al-Salem W, Acosta-Serrano A, et al. A new perspective on cutaneous leishmaniasis-implications for global prevalence and burden of disease estimates. PLoS Negl Trop Dis. 2017;11:e0005739. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28796782.

Reithinger R, Dujardin J-C, Louzir H, Pirmez C, Alexander B, Brooker S. Cutaneous leishmaniasis. Lancet Infect. Dis. 2007;7:581–96. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17714672.

Olliaro P, Grogl M, Boni M, Carvalho EM, Chebli H, Cisse M, et al. Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation. PLoS Negl Trop Dis. Public Library of Science. 2018;12:e0006141. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29329311.

Chernyshov PV, Zouboulis CC, Tomas-Aragones L, Jemec GB, Manolache L, Tzellos T, et al. Quality of Life Measurement in Acne. Position Paper of the European Academy of Dermatology and Venereology (EADV) Task Forces on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS). J Eur Acad Dermatology Venereol. 2017. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28898474.

Stavrou D, Weissman O, Tessone A, Zilinsky I, Holloway S, Boyd J, et al. Health related quality of life in burn patients--a review of the literature. Burns. 2014;40:788–96. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24433939.

Finnerty CC, Jeschke MG, Branski LK, Barret JP, Dziewulski P, Herndon DN. Hypertrophic scarring: the greatest unmet challenge after burn injury. Lancet. 2016;388:1427–36. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27707499.

Pandya AA, Corkill HA, Goutos I. Sexual function following burn injuries: literature review. J. Burn Care Res. 2015;36:e283-93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25423439.

Attoe C, Pounds-Cornish E. Psychosocial adjustment following burns: an integrative literature review. Burns. 2015;41:1375–84. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26359733.CrossRefPubMed

10.

de Zeeuw J, Omansen TF, Douwstra M, Barogui YT, Agossadou C, Sopoh GE, et al. Persisting social participation restrictions among former Buruli ulcer patients in Ghana and Benin. Small PLC, PLoS Negl Trop Dis. 2014;8:e3303. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25392915.

11.

Zeldenryk L, Gray M, Gordon S, Speare R, Hossain M. The use of focus groups to develop a culturally relevant quality of life tool for lymphatic filariasis in Bangladesh. Qual Life Res. 2014;23:299–309. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23793443.

12.

Thomas C, Narahari SR, Bose KS, Vivekananda K, Nwe S, West DP, et al. Comparison of three quality of life instruments in lymphatic filariasis: DLQI, WHODAS 2.0, and LFSQQ. PLoS Negl. Trop. Dis. 2014;8:e2716. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24587467.

13.

Mousley E, Deribe K, Tamiru A, Davey G. The impact of podoconiosis on quality of life in Northern Ethiopia. Health Qual Life Outcomes. 2013;11:122. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23866905.

14.

Lilly E, Lu PD, Borovicka JH, Victorson D, Kwasny MJ, West DP, et al. Development and validation of a vitiligo-specific quality-of-life instrument (VitiQoL). J am Acad Dermatol. 2013;69:e11-8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22365883.

15.

Gupta V, Sreenivas V, Mehta M, Khaitan BK, Ramam M. Measurement properties of the vitiligo impact Scale-22 (VIS-22), a vitiligo-specific quality-of-life instrument. Br J Dermatol. 2014;171:1084–90.CrossRefPubMed

16.

Senol A, Yucelten AD, Ay P. Development of a quality of life scale for vitiligo. Dermatology. 2013;226:185–90. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23735515.

17.

Thompson AR, Clarke SA, Newell RJ, Gawkrodger DJ. Vitiligo linked to stigmatization in British South Asian women: A qualitative study of the experiences of living with vitiligo. Br J Dermatol. 2010;163:481–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20426784.

18.

Thompson AR, Kent G, Smith JA. Living with vitiligo: Dealing with difference. Br J Health Psychol. 2002;7:213–25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14596710.

19.

Link BG, Phelan JC. Conceptualizing stigma. Annu Rev Sociol. 2001;363–85. Available from: http://www.annualreviews.org/doi/abs/10.1146/annurev.soc.27.1.363.

20.

Kalra S, Kelkar D, Galwankar SC, Papadimos TJ, Stawicki SP, Arquilla B, et al. The emergence of ebola as a global health security threat: from “lessons learned” to coordinated multilateral containment efforts. J Glob Infect Dis. 2014;6:164–77.CrossRefPubMedPubMedCentral

21.

Van Bortel T, Basnayake A, Wurie F, Jambai M, Koroma AS, Muana AT, et al. Psychosocial effects of an Ebola outbreak at individual, community and international levels. Bull World Heal. Organ. 2016;94:210–4.CrossRef

22.

Sampogna F, Sera F, Abeni D. Measures of clinical severity, quality of life, and psychological distress in patients with psoriasis: A cluster analysis. J Invest Dermatol. Elsevier. 2004;122:602–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15086541.

23.

Dowlatshahi EA, Wakkee M, Arends LR, Nijsten T. The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: a systematic review and meta-analysis. J Invest Dermatol. Elsevier; 2014;134:1542–51. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24284419.

24.

Wailoo K. Stigma, race, and disease in 20th century America. Lancet. 2006;367:531–3. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16473131.

25.

Goffman E. Stigma: notes on the management of spoiled identity, edition 2009. New York: Simon and Schuster, Inc; 1963.

26.

Hotez PJ. Stigma: the stealth weapon of the NTD. PLoS Negl Trop Dis. 2008;2:e230. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18446206.

27.

Weiss MG. Stigma and the social burden of neglected tropical diseases. PLoS Negl Trop Dis. 2008;2:e237.CrossRefPubMedPubMedCentral

28.

Gupta MA, Gupta AK. Cutaneous body image dissatisfaction and suicidal ideation: mediation by interpersonal sensitivity. J Psychosom Res. 2013;75:55–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23751239.

29.

Rumsey N, Harcourt D. Body image and disfigurement: issues and interventions. Body Image. 2004;1:83–97.CrossRefPubMed

30.

Gardiner MD, Topps A, Richardson G, Sacker A, Clarke A, Butler PE. Differential judgements about disfigurement: the role of location, age and gender in decisions made by observers. J Plast Reconstr Aesthet Surg. 2010; 63:73–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19084486.

31.

Bradbury E. Meeting the psychological needs of patients with facial disfigurement. Br J oral Maxillofac Surg. 2012;50:193–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21440966.

32.

Scambler G. Stigma and disease: changing paradigms. Lancet. 1998;352:1054–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9759769.

33.

Vogel DL, Bitman RL, Hammer JH, Wade NG. Is stigma internalized? The longitudinal impact of public stigma on self-stigma. J Couns Psychol. 2013;60:311–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23421775.

34.

Deacon H, Stephney I, Prosalendis S. Understanding HIV/AIDS stigma: a theoretical and methodological analysis. Cape Town: HSRC Press; 2005.

35.

Grant MJ, Booth A. A typology of reviews: An analysis of 14 review types and associated methodologies. Health Info Libr J. Blackwell Publishing Ltd; 2009. p. 91–108. Available from: http://doi.wiley.com/10.1111/j.1471-1842.2009.00848.x.

36.

Daudt HM, van Mossel C, Scott SJ. Enhancing the scoping study methodology: a large, inter-professional team’s experience with Arksey and O’Malley’s framework. BMC Med. Res. Methodol. 2013;13:48. Available from: http://bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-13-48.

37.

Arksey H, O’Malley L. Scoping studies: Towards a methodological framework. Int J Soc Res Methodol Theory Pract. 2005;8:19–32. Available from: http://www.tandfonline.com/doi/abs/10.1080/1364557032000119616.

38.

Peters MD, Godfrey CM, Khalil H, McInerney P, Parker D, Soares CB. Guidance for conducting systematic scoping reviews. Int J Evid Based Heal. 2015;13:141–6.CrossRef

39.

Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev BioMed Central. 2015;4:1. Available from: http://systematicreviewsjournal.biomedcentral.com/articles/10.1186/2046-4053-4-1.

40.

Reyburn H, Koggel M, Sharifi A. Social and psychological consequences of cutaneous leishmaniasis in Kabul, Afghanistan. Heal Int Partnersh with Nor Church Aid. 2000. Available from: http://www.afghandata.org:8080/xmlui/handle/azu/4484.

41.

Yanik M, Gurel MS, Simsek Z, Kati M. The psychological impact of cutaneous leishmaniasis. Clin Exp Dermatol. 2004;29:464–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15347324.

42.

Reithinger R, Aadil K, Kolaczinski J, Mohsen M, Hami S. Social impact of leishmaniasis, Afghanistan Emerg Infect Dis. 2005;11:634–636. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320322.

43.

Simsek Z, Ak D, Altindag A, Günes M. Prevalence and predictors of mental disorders among women in Sanliurfa, Southeastern Turkey. J Public Heal [Internet] 2008;30:487–493. Available from: https://doi.org/10.1093/pubmed/fdn025

44.

Kassi M, Kassi M, Afghan AK, Rehman R, Kasi PM. Marring Leishmaniasis: The Stigmatization and the Impact of Cutaneous Leishmaniasis in Pakistan and Afghanistan. PLoS Negl Trop Dis. 2008;2:3. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569210.

45.

Nilforoushzadeh MA, Roohafza H, Jaffary F, Khatuni M. Comparison of quality of life in women suffering from cutaneous leishmaniasis treated with topical and systemic glucantime along with psychiatric consultation compared with the group without psychiatric consultation. J Ski Leishmaniasis. 2010;1. Available from: http://jsl.mui.ac.ir/index.php/jsl/article/view/6.

46.

Fernando SD, Siriwardana H, Guneratne K, Rajapaksa LC. Some sociological aspects of cutaneous leishmaniasis in patients attending a tertiary referral Centre in Colombo, Sri Lanka. Int Health. 2010;2:69–74. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24037054.

47.

Abazid N, Jones C, Davies CR. Knowledge, attitudes and practices about leishmaniasis among cutaneous leishmaniasis patients in Aleppo, Syrian Arab Republic. East Mediterr heal J. 2012;18:7–14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22360005.

48.

Vares B, Mohseni M, Heshmatkhah A, Farjzadeh S, Safizadeh H, Shamsi-Meymandi S, et al. Quality of life in patients with cutaneous Leishmaniasis. Arch Iran Med. 2013;16:474–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23906253.

49.

Handjani F, Kalafi A. Impact of dermatological diseases on family members of the patients using family dermatology life quality index: a preliminary study in Iran. Iran J Dermatology. Tehran: Iranian society of Dermatology; 2013;16:128–131. Available from: http://www.iranjd.ir/download.asp?code=IJD131666128.

50.

Turan E, Kandemir H, Yesilova Y, Ekinci S, Tanrikulu O, Kandemir SB, et al. Assessment of psychiatric morbidity and quality of life in children and adolescents with cutaneous leishmaniasis and their parents. Postep Dermatologii I Alergol. 2015;32:344–8. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692819.

51.

Ramdas S, van der Geest S, Schallig H. Nuancing stigma through ethnography: the case of cutaneous leishmaniasis in Suriname. Soc Sci Med. 2016;151:139–46. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26802370.

52.

Chahed MK, Bellali H, Ben Jemaa S, Bellaj T. Psychological and psychosocial consequences of zoonotic cutaneous Leishmaniasis among women in Tunisia: preliminary findings from an exploratory study. PLoS Negl Trop Dis. 2016;10:e0005090. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27788184.

53.

Bennis I, Thys S, Filali H, De Brouwere V, Sahibi H, Boelaert M. Psychosocial impact of scars due to cutaneous leishmaniasis on high school students in Errachidia province, Morocco. Infect Dis Poverty. 2017;6:46. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383955.

54.

Al-Kamel MA. Stigmata in cutaneous leishmaniasis historical and new evidence based concepts. Our Dermatology Online 2017;

55.

Bennis I, Belaid L, De Brouwere V, Filali H, Sahibi H, Boelaert M. “The mosquitoes that destroy your face”. Social impact of cutaneous Leishmaniasis in South-Eastern Morocco, a qualitative study. PLoS One. 2017;12. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29261762.

56.

Semeneh. The psycho-social impact of cutaneous Leishmaniasis on people infected by the disease. Master thesis Addis Ababa Univ. Sch. Soc. Work. 2012;

57.

Costa JM, Vale KC, Cecílio IN, Osaki NK, Netto EM, Tada MS, et al. Aspectos psicossociais e estigmatizantes da leishmaniose cutâneo-mucosa. Rev Soc Bras Med Trop. 1987;20:77–81. Available from: http://dx.doi.org/10.1590/S0037-86821987000200003.

58.

Magalhaes HM, Costa JM, Costa RM, Franca F, Vale KC, Marsden P, et al. Information-related changes in attitude to mucocutaneous leishmaniasis of a population from an endemic region of the south of Bahia. Rev Soc Bras Med Trop. 1990;23:49–52.CrossRefPubMed

59.

Toledo Jr. AC, da Silva RE, Carmo RF, Amaral TA, Luz ZM, Rabello A. Assessment of the quality of life of patients with cutaneous leishmaniasis in Belo Horizonte, Brazil, 2009–2010. A pilot study. Trans R Soc Trop Med Hyg. 2013;107:335–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23474473.

60.

van ‘t Noordende AT, Kuiper H, Ramos Jr. AN, Mieras LF, Barbosa JC, Pessoa SM, et al. Towards a toolkit for cross-neglected tropical disease morbidity and disability assessment. Int Heal. 2016;8(Suppl 1):i71–81. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26940312.

61.

Weigel R. X. MMA. Genero e Leishmaniose Cut anea no Equador Rural: risco de doencca, gravidade e conseque ncias FIOCRUZ E, editor. Rio Janeiro. SciELO Books; 2000. Available from: http://books.scielo.org/id/45vyc/pdf/barata-9788575413944-13.pdf.

62.

Thompson A, Kent G. Adjusting to disfigurement: Processes involved in dealing with being visibly different. Clin Psychol Rev Pergamon; 2001. p. 663–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11434225.

63.

Wiechman SA, Patterson DR. ABC of burns. Psychosocial aspects of burn injuries. BMJ. BMJ publishing Group; 2004;329:391–393. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15310609.

64.

Kleinspehn-Ammerlahn A, Kotter-Gruhn D, Smith J. Self-perceptions of aging: do subjective age and satisfaction with aging change during old age? J Gerontol Ser B Psychol Sci Soc Sci. Oxford University Press; 2008;63:P377–85. Available from: http://doi.org/10.1093/geronb/63.6.P377.

65.

Demo DH. The self-concept over time: research issues and directions. Annu Rev Sociol. 1992;18:303–26. Available from: http://www.jstor.org/stable/2083456.

66.

Köber C, Habermas T. How stable is the personal past? Stability of most important autobiographical memories and life narratives across eight years in a life span sample. J Pers Soc Psychol. 2017;113:608–26. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28333472.

67.

Kensinger EA, Piguet O, Krendl AC, Corkin S. Memory for contextual details: effects of emotion and aging. Psychol Aging. 2005;20:241–50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16029088.

68.

Ebner NC, Fischer H. Emotion and aging: evidence from brain and behavior. Front Psychol. Frontiers media SA; 2014;5:996. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25250002.

69.

Egan M, Tannahill C, Petticrew M, Thomas S. Psychosocial risk factors in home and community settings and their associations with population health and health inequalities: a systematic meta-review. BMC Public Health. 2008;8:239–52. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18631374.

70.

Alvar J, Yactayo S, Bern C. Leishmaniasis and poverty. Trends Parasitol. 2006;22:552–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17023215.

71.

Hofstraat K, van Brakel WH. Social stigma towards neglected tropical diseases: a systematic review. Int Health. 2016;8:i53–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26940310.

72.

Okwa OO. Tropical parasitic diseases and women. Ann Afr Med. 2007;6:157–63. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18354939.

73.

Okwor I, Uzonna J. Social and economic burden of human leishmaniasis. Am J Trop Med Hyg. 2016;94:489–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26787156.

74.

Homsi YMG. Leishmaniasis: a forgotten disease among neglected people. Internet J Heal. 2009;11. Available from: http://ispub.com/IJH/11/2/9151.

75.

Moya L, Alvar J. Enfermedades tropicales desatendidas estigmatizantes: una revisión sistemática. Med Soc. 2011;246–58. Available from: http://www.medicinasocial.info/index.php/medicinasocial/article/view/471.

Title: Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review
Authors: Issam Bennis
Vincent De Brouwere
Zakaria Belrhiti
Hamid Sahibi
Marleen Boelaert
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Public Health / Issue 1/2018
Electronic ISSN: 1471-2458
DOI: https://doi.org/10.1186/s12889-018-5260-9

At a glance: The STEP trials

Springer Medicine

Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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