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International Journal of Clinical Oncology

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01-02-2017 | Original Article

Psychological impact of positive cervical cancer screening results among Japanese women

Authors: Yukari Isaka, Haruhiko Inada, Yuri Hiranuma, Masao Ichikawa

Published in: International Journal of Clinical Oncology | Issue 1/2017

Abstract

Background

While cervical cancer screening is useful for detecting and then treating the disease at an early stage, most women with screen-positive results are free from cervical cancer but nevertheless subject to the unnecessary worry entailed in receiving such results. The purpose of this study was to examine whether receiving a screen-positive result was actually related to psychological distress among Japanese women who underwent cervical cancer screening.

Methods

We conducted a questionnaire survey at health facilities in a semiurban city of Ibaraki prefecture, involving 1744 women who underwent cervical cancer screening and 72 who received screen-positive results and then underwent further testing. We used the K6 scale to assess their psychological distress (K6 score ≥5) and performed multiple logistic regression analyses to estimate the relative effect of receiving screen-positive results on psychological distress.

Results

Psychological distress was more prevalent among women with screen-positive results (OR 2.22; 95 % CI 1.32–3.74), while it was also related to history of mental health consultation (OR 2.26; 95 % CI 1.69–3.01) and marital status (OR 1.32; 95 % CI 1.02–1.70).

Conclusions

Receiving a positive cervical cancer screening result was associated with psychological distress. To alleviate this psychological impact, the current form of communicating the screening results should be reconsidered.

Ferlay J, Soerjomataram I, Dikshit R et al (2015) Cancer incidence and mortality worldwide. Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136:E359–E386. doi:10.1002/ijc.29210 CrossRefPubMed

Matsuda A, Matsuda T, Shibata A et al (2014) Cancer incidence and incidence rates in Japan in 2008: a study of 25 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project. Jpn J Clin Oncol 44:388–396. doi:10.1093/jjco/hyu003 CrossRefPubMed

Ministry of Health, Labour and Welfare (2013) Vital Statistics Japan. http://ganjoho.jp/data/reg_stat/statistics/dl/cancer_mortality(1958-2013).xls. Accessed Sep 2015

Hamashima C, Aoki D, Miyagi E et al (2010) The Japanese guideline for cervical cancer screening. Jpn J Clin Oncol 40:485–502. doi:10.1093/jjco/hyq036 CrossRefPubMed

Aklimunnessa K, Mori M, Khan MM et al (2006) Effectiveness of cervical cancer screening over cervical cancer mortality among Japanese women. Jpn J Clin Oncol 36:511–518. doi:10.1093/jjco/hyl060 CrossRefPubMed

Lerman C, Miller SM, Scarborough R et al (1991) Adverse psychologic consequences of positive cytologic cervical screening. Am J Obstet Gynecol 165:658–662CrossRefPubMed

Idestrom M, Milsom I, Andersson-Ellstrom A (2003) Women’s experience of coping with a positive Pap smear: a register-based study of women with two consecutive Pap smears reported as CIN 1. Acta Obstet Gynecol Scand 82:756–761CrossRefPubMed

Gray NM, Sharp L, Cotton SC et al (2006) Psychological effects of a low-grade abnormal cervical smear test result: anxiety and associated factors. Br J Cancer 94:1253–1262. doi:10.1038/sj.bjc.6603086 CrossRefPubMedPubMedCentral

Korfage IJ, Van Ballegooijen M, Huveneers H et al (2010) Anxiety and borderline PAP smear results. Eur J Cancer 46:134–141. doi:10.1016/j.ejca.2009.07.003 CrossRefPubMed

10.

National Cancer Center (2011) Cancer Registry and Statistics. Cancer Information Service, National Cancer Center. http://ganjoho.jp/data/reg_stat/statistics/dl/Pref_Cancer_screening_process_indicator(2008-2011).xls. Accessed Sep 2015

11.

Kessler RC, Andrews G, Colpe LJ et al (2002) Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med 32:959–976CrossRefPubMed

12.

Kessler RC, Barker PR, Colpe LJ et al (2003) Screening for serious mental illness in the general population. Arch Gen Psychiatry 60:184–189CrossRefPubMed

13.

Furukawa TA, Kawakami N, Saitoh M et al (2008) The performance of the Japanese version of the K6 and K10 in the World Mental Health Survey Japan. Int J Methods Psychiatr Res 17:152–158. doi:10.1002/mpr.257 CrossRefPubMed

14.

Sakurai K, Nishi A, Kondo K et al (2011) Screening performance of K6/K10 and other screening instruments for mood and anxiety disorders in Japan. Psychiatry Clin Neurosci 65:434–441. doi:10.1111/j.1440-1819.2011.02236.x CrossRefPubMed

15.

Kessler RC, Green JG, Gruber MJ et al (2010) Screening for serious mental illness in the general population with the K6 screening scale: results from the WHO World Mental Health (WMH) survey initiative. Int J Methods Psychiatr Res 19(Suppl 1):4–22. doi:10.1002/mpr.310 CrossRefPubMedPubMedCentral

16.

Sakurai K, Kawakami N, Yamaoka K et al (2010) The impact of subjective and objective social status on psychological distress among men and women in Japan. Soc Sci Med 70:1832–1839. doi:10.1016/j.socscimed.2010.01.019 CrossRefPubMed

17.

Hellsten C, Sjostrom K, Lindqvist PG (2008) A 2-year follow-up study of anxiety and depression in women referred for colposcopy after an abnormal cervical smear. BJOG 115:212–218. doi:10.1093/jjco/hyq036 CrossRefPubMed

18.

French DP, Maissi E, Marteau TM (2004) Psychological costs of inadequate cervical smear test results. Br J Cancer 91:1887–1892. doi:10.1038/sj.bjc.6602224 CrossRefPubMedPubMedCentral

19.

Wilkinson C, Jones JM, Mcbride J (1990) Anxiety caused by abnormal result of cervical smear test: a controlled trial. BMJ 300:440CrossRefPubMedPubMedCentral

Title: Psychological impact of positive cervical cancer screening results among Japanese women
Authors: Yukari Isaka
Haruhiko Inada
Yuri Hiranuma
Masao Ichikawa
Publication date: 01-02-2017
Publisher: Springer Japan
Published in: International Journal of Clinical Oncology / Issue 1/2017
Print ISSN: 1341-9625
Electronic ISSN: 1437-7772
DOI: https://doi.org/10.1007/s10147-016-1023-8

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Abstract

Background

Methods

Results

Conclusions

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