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Supportive Care in Cancer
Published in: Supportive Care in Cancer 9/2003

01-09-2003 | Original Article

Pseudomembranous and neutropenic enterocolitis in pediatric oncology patients

Authors: M. D. van de Wetering, T. W. Kuijpers, J. A. J. M. Taminiau, F. J. W. ten Kate, H. N. Caron

Published in: Supportive Care in Cancer | Issue 9/2003

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Abstract

Neutropenic enterocolitis in oncological patients represents a wide spectrum of clinicopathological pictures each with its own entity. Early diagnosis of enterocolitis can lead to improved supportive care and therefore better outcome. We present two cases—patient A, a child with pseudomembranous colitis caused by Clostridium difficile, and patient B, a child with neutropenic enterocolitis, where no organism was found. By allowing an insight into the pathology, immunology and culture results, we demonstrated that early diagnosis leads to improved management and therefore improved outcome.
Literature
1.
Anand A, Bashey B, Mir T, Glatt AE (1994) Epidemiology, clinical manifestations, and outcome of Clostridium difficile-associated diarrhea. Am J Gastroenterol 89:519–523PubMed
2.
de Bont ES, Vellenga E, Swaanenburg JC, Fidler V, Visser-van Brummen PJ, Kamps WA (1999) Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia. Br J Haematol 107:375–380CrossRefPubMed
3.
Ettinghausen SE (1993) Collagenous colitis, eosinophilic colitis, and neutropenic colitis. Surg Clin North Am 73:993–1016PubMed
4.
Fekety R (1997) Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis. American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 92:739–750PubMed
5.
Ferrazzi E, Toso S, Zanotti M, Giuliano G (2001) Typhlitis (neutropenic enterocolitis) after a single dose of vinorelbine. Cancer Chemother Pharmacol 47:277–279CrossRefPubMed
6.
Gomez L, Martino R, Rolston KV (1998) Neutropenic enterocolitis: spectrum of the disease and comparison of definite and possible cases. Clin Infect Dis 27:695–699PubMed
7.
Karakurum M, Shreeniwas R, Chen J, Pinsky D, Yan SD, Anderson M, Sunouchi K, Major J, Hamilton T, Kuwabara K (1994) Hypoxic induction of interleukin-8 gene expression in human endothelial cells. J Clin Invest 93:1564–1570PubMed
8.
9.
Price AB, Davies DR (1977) Pseudomembranous colitis. J Clin Pathol 30:1–12PubMed
10.
Riley TV (1998) Clostridium difficile: a pathogen of the nineties. Eur J Clin Microbiol Infect Dis 17:137–141PubMed
11.
Schuller I, Saha V, Kingston J, Eden T (1995) Investigation and management of Clostridium difficile colonisation in a paediatric oncology unit. 72:219–222
12.
Shamberger RC, Weinstein HJ, Delorey MJ, Levey RH (1986) The medical and surgical management of typhlitis in children with acute nonlymphocytic (myelogenous) leukemia. Cancer 57:603–609PubMed
13.
Sloas MM, Flynn PM, Kaste SC, Patrick CC (1993) Typhlitis in children with cancer: a 30-year experience. Clin Infect Dis 17:484–490PubMed
14.
Weinberger M, Hollingsworth H, Feuerstein IM, Young NS, Pizzo PA (1993) Successful surgical management of neutropenic enterocolitis in two patients with severe aplastic anemia. Case reports and review of the literature. Arch Intern Med 153:107–113CrossRefPubMed
Metadata
Title
Pseudomembranous and neutropenic enterocolitis in pediatric oncology patients
Authors
M. D. van de Wetering
T. W. Kuijpers
J. A. J. M. Taminiau
F. J. W. ten Kate
H. N. Caron
Publication date
01-09-2003
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 9/2003
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-003-0483-3

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