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Indian Journal of Hematology and Blood Transfusion

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01-09-2014 | Case Report

Pseudo Chediak-Higashi Granules in Acute Lymphoblastic Leukemia: A Rare Entity

Authors: Pallavi Agrawal, Narender Kumar, Prashant Sharma, Subhash Varma, Neelam Varma

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 3/2014

Abstract

Pseudo-Chediak-Highashi granules are giant cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. They derive their name from the inherited Chediak-Higashi syndrome that presents with oculocutaneous albinism, chronic infections and platelet dense granule deficiency. We report possibly the third case in world literature where these granules were seen in the blast cells of acute lymphoblastic leukemia in a 15-year-old male.

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Title: Pseudo Chediak-Higashi Granules in Acute Lymphoblastic Leukemia: A Rare Entity
Authors: Pallavi Agrawal
Narender Kumar
Prashant Sharma
Subhash Varma
Neelam Varma
Publication date: 01-09-2014
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 3/2014
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-012-0206-3

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