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Published in: European Journal of Pediatrics 9/2003

01-09-2003 | Original Paper

Pseudo-Bartter syndrome in a neonate on prostaglandin infusion

Authors: Sofie Vanhaesebrouck, Karel Allegaert, Christine Vanhole, Hugo Devlieger, Marc Gewillig, Willem Proesmans

Published in: European Journal of Pediatrics | Issue 9/2003

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Abstract

We describe a case of iatrogenic pseudo-Bartter syndrome caused by administration of prostaglandin E1 (PGE1 alprostadil). Although the use of i.v. PGE1 is a well-established pharmacological therapy in neonates with a ductus-dependent congenital cardiopathy to ensure ductus-dependent flow, we could only find one other report on pseudo-Bartter syndrome related to PGE1 infusion. Conclusion: primary Bartter syndrome is associated with endogenous increased levels of prostaglandins. Therefore, we postulate that the dose of prostaglandin E1 administered, immaturity and the genetic background are all relevant factors involved in the phenotypic presentation of iatrogenic pseudo-Bartter syndrome in this preterm infant.
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Metadata
Title
Pseudo-Bartter syndrome in a neonate on prostaglandin infusion
Authors
Sofie Vanhaesebrouck
Karel Allegaert
Christine Vanhole
Hugo Devlieger
Marc Gewillig
Willem Proesmans
Publication date
01-09-2003
Publisher
Springer-Verlag
Published in
European Journal of Pediatrics / Issue 9/2003
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-003-1201-3

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