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Osteoporosis International

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Open Access 01-05-2011 | Letter

Proton pump inhibitors, fracture risk and selection bias: three studies, same database, two answers

Authors: F. de Vries, T.-P. van Staa, H. G. M. Leufkens

Published in: Osteoporosis International | Issue 5/2011

Excerpt

Dear Editor, …

de Vries F, de Vries C, Cooper C, Leufkens B, van Staa T-P (2006) Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database. Int J Epidemiol 35:1301–1308PubMedCrossRef

US Food and Drug Administration FDA (2010) Possible fracture risk with high dose, long-term use of proton pump inhibitors. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed 28 May 2010

Yang YX, Lewis JD, Epstein S, Metz DC (2006) Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 296:2947–2953PubMedCrossRef

Kaye JA, Jick H (2008) Proton pump inhibitor use and risk of hip fractures in patients without major risk factors. Pharmacotherapy 28:951–959PubMedCrossRef

de Vries F, Cooper AL, Cockle SM, van Staa TP, Cooper C (2009) Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates. Osteoporos Int 20:1989–1998PubMedCrossRef

Lalmohamed A, Pouwels S, Cooper C, van Staa TP, Leufkens B, de Boer A, de Vries F (2009) Use of proton pump inhibitors and risk of hip fracture. Bone 44(Suppl2):S396–S397CrossRef

Title: Proton pump inhibitors, fracture risk and selection bias: three studies, same database, two answers
Authors: F. de Vries
T.-P. van Staa
H. G. M. Leufkens
Publication date: 01-05-2011
Publisher: Springer-Verlag
Published in: Osteoporosis International / Issue 5/2011
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-010-1323-1

At a glance: The STEP trials

Springer Medicine

Proton pump inhibitors, fracture risk and selection bias: three studies, same database, two answers

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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