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Indian Journal of Otolaryngology and Head & Neck Surgery

Published in:

01-10-2019 | Original Article

Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer

Authors: Yusuke Azami, Yuichiro Hayashi, Tatsuya Nakamura, Kanako Kimura, Hisashi Yamaguchi, Takashi Ono, Kanako Takayama, Katsumi Hirose, Tomonori Yabuuchi, Motohisa Suzuki, Yoshiomi Hatayama, Masato Hareyama, Yasuhiro Kikuchi, Nobukazu Fuwa

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 1/2019

Abstract

The aim of this study was to evaluate the efficacy and safety of proton beam therapy for patients with locally recurrent parotid cancer. Between 2009 and 2012, ten patients with locally recurrent parotid gland cancer were treated with proton beam therapy (70.2 Gy equivalents in 32 fractions) with or without intra-arterial infusion chemotherapy of cisplatin (50 mg/body/week, for a total of 5–8 weeks). The median follow-up was 24 months (range 10–49 months). The 1-year overall survival and local control rates were 80 %, and the 3-year overall survival and local control rates were 60 %. None of the patients experienced grade 3–5 toxicities in the treatment or the follow-up periods. These findings suggest that proton beam therapy could be applied effectively and safely for patients with locally recurrent parotid gland cancer.

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Title: Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer
Authors: Yusuke Azami
Yuichiro Hayashi
Tatsuya Nakamura
Kanako Kimura
Hisashi Yamaguchi
Takashi Ono
Kanako Takayama
Katsumi Hirose
Tomonori Yabuuchi
Motohisa Suzuki
Yoshiomi Hatayama
Masato Hareyama
Yasuhiro Kikuchi
Nobukazu Fuwa
Publication date: 01-10-2019
Publisher: Springer India
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 1/2019
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-016-1008-y

At a glance: The STEP trials

Springer Medicine

Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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