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Published in: BMC Geriatrics 1/2007

Open Access 01-12-2007 | Study protocol

Protocol for Fit Bodies, Fine Minds: a randomized controlled trial on the affect of exercise and cognitive training on cognitive functioning in older adults

Authors: Siobhan T O'Dwyer, Nicola W Burton, Nancy A Pachana, Wendy J Brown

Published in: BMC Geriatrics | Issue 1/2007

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Abstract

Background

Declines in cognitive functioning are a normal part of aging that can affect daily functioning and quality of life. This study will examine the impact of an exercise training program, and a combined exercise and cognitive training program, on the cognitive and physical functioning of older adults.

Methods/Design

Fit Bodies, Fine Minds is a randomized, controlled trial. Community-dwelling adults, aged between 65 and 75 years, are randomly allocated to one of three groups for 16 weeks. The exercise-only group do three 60-minute exercise sessions per week. The exercise and cognitive training group do two 60-minute exercise sessions and one 60-minute cognitive training session per week. A no-training control group is contacted every 4 weeks. Measures of cognitive functioning, physical fitness and psychological well-being are taken at baseline (0 weeks), post-test (16 weeks) and 6-month follop (40 weeks). Qualitative responses to the program are taken at post-test.

Discussion

With an increasingly aged population, interventions to improve the functioning and quality of life of older adults are particularly important. Exercise training, either alone or in combination with cognitive training, may be an effective means of optimizing cognitive functioning in older adults. This study will add to the growing evidence base on the effectiveness of these interventions.

Trial Registration

Australian Clinical Trials Register: ACTRN012607000151437
Appendix
Available only for authorised users
Literature
1.
go back to reference Schaie KW: The course of adult intellectual development. American Psychologist. 1994, 49: 304-313. 10.1037/0003-066X.49.4.304.CrossRefPubMed Schaie KW: The course of adult intellectual development. American Psychologist. 1994, 49: 304-313. 10.1037/0003-066X.49.4.304.CrossRefPubMed
2.
go back to reference Hultsch DF, Hertzog C, Small BJ, McDonald-Miszczak L, Dixon RA: Short-term longitudinal change in cognitive performance in later life. Psychology and Aging. 1992, 7: 571-584. 10.1037/0882-7974.7.4.571.CrossRefPubMed Hultsch DF, Hertzog C, Small BJ, McDonald-Miszczak L, Dixon RA: Short-term longitudinal change in cognitive performance in later life. Psychology and Aging. 1992, 7: 571-584. 10.1037/0882-7974.7.4.571.CrossRefPubMed
3.
go back to reference Cullum S, Huppert FA, McGee M, Dening T, Ahmed A, Paykel ES, Brayne C: Decline across different domains of cognitive function in normal ageing: Results of a longitudinal population-based study using CAMCOG. International Journal of Geriatric Psychiatry. 2000, 15: 853-862. 10.1002/1099-1166(200009)15:9<853::AID-GPS211>3.0.CO;2-T.CrossRefPubMed Cullum S, Huppert FA, McGee M, Dening T, Ahmed A, Paykel ES, Brayne C: Decline across different domains of cognitive function in normal ageing: Results of a longitudinal population-based study using CAMCOG. International Journal of Geriatric Psychiatry. 2000, 15: 853-862. 10.1002/1099-1166(200009)15:9<853::AID-GPS211>3.0.CO;2-T.CrossRefPubMed
4.
go back to reference Singer T, Verghaeghen P, Ghisletta P, Lindenberger U, Baltes PB: The fate of cognition in very old age: Six-year longitudinal findings in the Berlin Aging Study (BASE). Psychology and Aging. 2003, 18: 318-331. 10.1037/0882-7974.18.2.318.CrossRefPubMed Singer T, Verghaeghen P, Ghisletta P, Lindenberger U, Baltes PB: The fate of cognition in very old age: Six-year longitudinal findings in the Berlin Aging Study (BASE). Psychology and Aging. 2003, 18: 318-331. 10.1037/0882-7974.18.2.318.CrossRefPubMed
5.
go back to reference Rabbitt PMA, McInnes L, Diggle P, Holland F, Bent N, Abson V, Pendleton N, Horan M: The University of Manchester Longitudinal Study of cognition in normal healthy old age, 1983 through 2003. Aging, Neuropsychology and Cognition. 2004, 11: 245-279.CrossRef Rabbitt PMA, McInnes L, Diggle P, Holland F, Bent N, Abson V, Pendleton N, Horan M: The University of Manchester Longitudinal Study of cognition in normal healthy old age, 1983 through 2003. Aging, Neuropsychology and Cognition. 2004, 11: 245-279.CrossRef
6.
go back to reference Cahn-Weiner DA, Boyle PA, Malloy PF: Tests of executive function predict instrumental activities of daily living in community-dwelling older individuals. Applied Neuropsychology. 2002, 9: 187-191. 10.1207/S15324826AN0903_8.CrossRefPubMed Cahn-Weiner DA, Boyle PA, Malloy PF: Tests of executive function predict instrumental activities of daily living in community-dwelling older individuals. Applied Neuropsychology. 2002, 9: 187-191. 10.1207/S15324826AN0903_8.CrossRefPubMed
7.
go back to reference Zimmerman T, McDougall GJ, Becker H: Older women's cognitive and affective response to moderate drinking. International Journal of Geriatric Psychiatry. 2004, 19: 1095-1102. 10.1002/gps.1216.CrossRefPubMedPubMedCentral Zimmerman T, McDougall GJ, Becker H: Older women's cognitive and affective response to moderate drinking. International Journal of Geriatric Psychiatry. 2004, 19: 1095-1102. 10.1002/gps.1216.CrossRefPubMedPubMedCentral
8.
go back to reference Jonsson L, Lindgren P, Wimo A, Jonsson B, Winblad B: Costs of Mini Mental State Examination-related cognitive impairment. Pharmacoeconomics. 1999, 16: 409-416. 10.2165/00019053-199916040-00008.CrossRefPubMed Jonsson L, Lindgren P, Wimo A, Jonsson B, Winblad B: Costs of Mini Mental State Examination-related cognitive impairment. Pharmacoeconomics. 1999, 16: 409-416. 10.2165/00019053-199916040-00008.CrossRefPubMed
9.
go back to reference Pedersen BK, Saltin B: Evidence for prescribing exercise as therapy in chronic disease. Scandinavian Journal of Medicine & Science in Sports. 2006, 16: 3-63. 10.1111/j.1600-0838.2006.00520.x.CrossRef Pedersen BK, Saltin B: Evidence for prescribing exercise as therapy in chronic disease. Scandinavian Journal of Medicine & Science in Sports. 2006, 16: 3-63. 10.1111/j.1600-0838.2006.00520.x.CrossRef
10.
go back to reference Colcombe SJ, Kramer AF, McAuley E, Erickson KI, Scalf P: Neurocognitive aging and cardiovascular fitness: Recent findings and future directions. Journal of Molecular Neuroscience. 2004, 24: 9-14. 10.1385/JMN:24:1:009.CrossRefPubMed Colcombe SJ, Kramer AF, McAuley E, Erickson KI, Scalf P: Neurocognitive aging and cardiovascular fitness: Recent findings and future directions. Journal of Molecular Neuroscience. 2004, 24: 9-14. 10.1385/JMN:24:1:009.CrossRefPubMed
11.
go back to reference Dustman RE, Emmerson R, Shearer D: Physical activity, age, and cognitive-neuropsychological function. Journal of Aging and Physical Activity. 1994, 2: 143-181. Dustman RE, Emmerson R, Shearer D: Physical activity, age, and cognitive-neuropsychological function. Journal of Aging and Physical Activity. 1994, 2: 143-181.
12.
go back to reference Clarkson-Smith L, Hartley AA: Relationships between physical exercise and cognitive abilities in older adults. Psychology and Aging. 1989, 4: 183-189. 10.1037/0882-7974.4.2.183.CrossRefPubMed Clarkson-Smith L, Hartley AA: Relationships between physical exercise and cognitive abilities in older adults. Psychology and Aging. 1989, 4: 183-189. 10.1037/0882-7974.4.2.183.CrossRefPubMed
13.
go back to reference Roth DL, Goode KT, Clay OJ, Ball KK: Association of physical activity and visual attention in older adults. Journal of Aging and Health. 2003, 15: 534-547. 10.1177/0898264303253512.CrossRefPubMed Roth DL, Goode KT, Clay OJ, Ball KK: Association of physical activity and visual attention in older adults. Journal of Aging and Health. 2003, 15: 534-547. 10.1177/0898264303253512.CrossRefPubMed
14.
go back to reference Yaffe K, Barnes D, Nevitt M, Lui LY, Covinsky K: A prospective study of physical activity and cognitive decline in elderly women: Women who walk. Archives of Internal Medicine. 2001, 161: 1703-1708. 10.1001/archinte.161.14.1703.CrossRefPubMed Yaffe K, Barnes D, Nevitt M, Lui LY, Covinsky K: A prospective study of physical activity and cognitive decline in elderly women: Women who walk. Archives of Internal Medicine. 2001, 161: 1703-1708. 10.1001/archinte.161.14.1703.CrossRefPubMed
15.
go back to reference Weuve J, Kang JH, Manson JE, Breteler MMB, Ware JH, Grodstein F: Physical activity, including walking, and cognitive function in older women. JAMA. 2004, 292: 1454-1461. 10.1001/jama.292.12.1454.CrossRefPubMed Weuve J, Kang JH, Manson JE, Breteler MMB, Ware JH, Grodstein F: Physical activity, including walking, and cognitive function in older women. JAMA. 2004, 292: 1454-1461. 10.1001/jama.292.12.1454.CrossRefPubMed
16.
go back to reference Pignatti F, Rozzini R, Trabucchi M: Physical activity and cognitive decline in elderly persons. Archives of Internal Medicine. 2002, 162: 361-362. 10.1001/archinte.162.3.361.CrossRefPubMed Pignatti F, Rozzini R, Trabucchi M: Physical activity and cognitive decline in elderly persons. Archives of Internal Medicine. 2002, 162: 361-362. 10.1001/archinte.162.3.361.CrossRefPubMed
17.
go back to reference Barnes D, Yaffe K, Satariano WA, Tager IB: A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults. JAGS. 2003, 51: 459-465. 10.1046/j.1532-5415.2003.51153.x.CrossRef Barnes D, Yaffe K, Satariano WA, Tager IB: A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults. JAGS. 2003, 51: 459-465. 10.1046/j.1532-5415.2003.51153.x.CrossRef
18.
go back to reference van Gelder BM, Tijhuis MAR, Kalmijn S, Giampaoli S, Nissinen A, Kromhout D: Physical activity in relation to cognitive decline in elderly men: The FINE Study. Neurology. 2004, 63: 2316-2321.CrossRefPubMed van Gelder BM, Tijhuis MAR, Kalmijn S, Giampaoli S, Nissinen A, Kromhout D: Physical activity in relation to cognitive decline in elderly men: The FINE Study. Neurology. 2004, 63: 2316-2321.CrossRefPubMed
19.
go back to reference Dustman RE, Ruhling RO, Russell EM, Shearer DE, Bonekat HW, Shigeoka JW, Wood JS, Bradford DC: Aerobic exercise training and improved neuropsychological function of older individuals. Neurobiology of Aging. 1984, 5: 35-42. 10.1016/0197-4580(84)90083-6.CrossRefPubMed Dustman RE, Ruhling RO, Russell EM, Shearer DE, Bonekat HW, Shigeoka JW, Wood JS, Bradford DC: Aerobic exercise training and improved neuropsychological function of older individuals. Neurobiology of Aging. 1984, 5: 35-42. 10.1016/0197-4580(84)90083-6.CrossRefPubMed
20.
go back to reference Moul JL, Goldman B, Warren B: Physical activity and cognitive performance in the older population. Journal of Aging and Physical Activity. 1995, 3: 135-145. Moul JL, Goldman B, Warren B: Physical activity and cognitive performance in the older population. Journal of Aging and Physical Activity. 1995, 3: 135-145.
21.
go back to reference Kramer AF, Hahn S, Cohen NJ, Banich MT, McAuley E, Harrison CR, Chason J, Vakil E, Bardell L, Boileau RA, Colcombe A: Ageing, fitness and neurocognitive function. Nature. 1999, 400: 418-419. 10.1038/22682.CrossRefPubMed Kramer AF, Hahn S, Cohen NJ, Banich MT, McAuley E, Harrison CR, Chason J, Vakil E, Bardell L, Boileau RA, Colcombe A: Ageing, fitness and neurocognitive function. Nature. 1999, 400: 418-419. 10.1038/22682.CrossRefPubMed
22.
go back to reference Blumenthal JA, Emery CF, Madden DJ, Schniebolk S, Walsh-Riddle M, George LK, McKee DC, Higginbotham MB, Cobb FR, Coleman RE: Long-term effects of exercise on psychological functioning in older men and women. Journal of Gerontology. 1991, 46: 352-361.CrossRef Blumenthal JA, Emery CF, Madden DJ, Schniebolk S, Walsh-Riddle M, George LK, McKee DC, Higginbotham MB, Cobb FR, Coleman RE: Long-term effects of exercise on psychological functioning in older men and women. Journal of Gerontology. 1991, 46: 352-361.CrossRef
23.
go back to reference Blumenthal JA, Madden DJ: Effects of aerobic exercise training, age, and physical fitness on memory-search performance. Psychology and Aging. 1988, 3: 280-285. 10.1037/0882-7974.3.3.280.CrossRefPubMed Blumenthal JA, Madden DJ: Effects of aerobic exercise training, age, and physical fitness on memory-search performance. Psychology and Aging. 1988, 3: 280-285. 10.1037/0882-7974.3.3.280.CrossRefPubMed
24.
go back to reference Hill RD, Storandt M, Malley M: The impact of long-term exercise training on psychological function in older adults. Journals of Gerontology: Psychological Sciences. 1993, 48: P12-P17.CrossRef Hill RD, Storandt M, Malley M: The impact of long-term exercise training on psychological function in older adults. Journals of Gerontology: Psychological Sciences. 1993, 48: P12-P17.CrossRef
25.
go back to reference Colcombe S, Kramer AF: Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychological Science. 2003, 14: 125-130. 10.1111/1467-9280.t01-1-01430.CrossRefPubMed Colcombe S, Kramer AF: Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychological Science. 2003, 14: 125-130. 10.1111/1467-9280.t01-1-01430.CrossRefPubMed
26.
go back to reference Colcombe SJ, Erickson KI, Raz N, Webb AG, Cohen NJ, McAuley E, Kramer AF: Aerobic fitness reduces brain tissue loss in aging humans. Journal of Gerontology: Medical Sciences. 2003, 58A: 176-180. Colcombe SJ, Erickson KI, Raz N, Webb AG, Cohen NJ, McAuley E, Kramer AF: Aerobic fitness reduces brain tissue loss in aging humans. Journal of Gerontology: Medical Sciences. 2003, 58A: 176-180.
27.
go back to reference Rogers RL, Meyer JS, Mortel KF: After reaching retirement age physical activity sustains cerebral perfusion and cognition. JAGS. 1990, 38: 123-128.CrossRef Rogers RL, Meyer JS, Mortel KF: After reaching retirement age physical activity sustains cerebral perfusion and cognition. JAGS. 1990, 38: 123-128.CrossRef
28.
go back to reference Poon LW, Chodzko-Zajko W, Tomporowski PD: Active Living, Cognitive Functioning, and Aging. Aging, Exercise and Cognition Series. Edited by: Poon LW, Spirduso WW and Chodzko-Zajko W. 2006, Champaign, IL, Human Kinetics, 1: Poon LW, Chodzko-Zajko W, Tomporowski PD: Active Living, Cognitive Functioning, and Aging. Aging, Exercise and Cognition Series. Edited by: Poon LW, Spirduso WW and Chodzko-Zajko W. 2006, Champaign, IL, Human Kinetics, 1:
29.
go back to reference Madden DJ, Blumenthal JA, Allen PA, Emery CF: Improving aerobic capacity in healthy older adults does not necessarily lead to improved cognitive performance. Psychology and Aging. 1989, 4: 307-320. 10.1037/0882-7974.4.3.307.CrossRefPubMed Madden DJ, Blumenthal JA, Allen PA, Emery CF: Improving aerobic capacity in healthy older adults does not necessarily lead to improved cognitive performance. Psychology and Aging. 1989, 4: 307-320. 10.1037/0882-7974.4.3.307.CrossRefPubMed
30.
go back to reference Spirduso WW: Active Living, Cognitive Functioning, and Aging. 2006, Champaign, IL, Human Kinetics, 1: 187-195. Issues of aging, physical activity, cognition, and putative mechanisms for a relationship: A discussion. Poon LW, Chodzko-Zajko W and Tomporowski PD, Aging, Exercise and Cognition Series, Poon LW, Spirduso WW, Chodzko-Zajko W. Spirduso WW: Active Living, Cognitive Functioning, and Aging. 2006, Champaign, IL, Human Kinetics, 1: 187-195. Issues of aging, physical activity, cognition, and putative mechanisms for a relationship: A discussion. Poon LW, Chodzko-Zajko W and Tomporowski PD, Aging, Exercise and Cognition Series, Poon LW, Spirduso WW, Chodzko-Zajko W.
31.
go back to reference Dunn AL, Trivedi MH, Kampert JB, Clark CG, Chambliss HO: Exercise treatment for depression: Efficacy and dose response. Am J Prev Med. 2005, 28: 1-8. 10.1016/j.amepre.2004.09.003.CrossRefPubMed Dunn AL, Trivedi MH, Kampert JB, Clark CG, Chambliss HO: Exercise treatment for depression: Efficacy and dose response. Am J Prev Med. 2005, 28: 1-8. 10.1016/j.amepre.2004.09.003.CrossRefPubMed
32.
go back to reference Yaffe K, Blackwell T, Gore R, Sands L, Reus V, Browner WS: Depressive symptoms and cognitive decline in nondemented elderly women: A prospective study. Archives of General Psychiatry. 1999, 56: 425-10.1001/archpsyc.56.5.425.CrossRefPubMed Yaffe K, Blackwell T, Gore R, Sands L, Reus V, Browner WS: Depressive symptoms and cognitive decline in nondemented elderly women: A prospective study. Archives of General Psychiatry. 1999, 56: 425-10.1001/archpsyc.56.5.425.CrossRefPubMed
33.
go back to reference Lee C, Russell A: Effects of physical activity on emotional well-being among older Australian women: Cross-sectional and longitudinal analyses. Journal of Psychosomatic Research. 2003, 54: 155-160. 10.1016/S0022-3999(02)00414-2.CrossRefPubMed Lee C, Russell A: Effects of physical activity on emotional well-being among older Australian women: Cross-sectional and longitudinal analyses. Journal of Psychosomatic Research. 2003, 54: 155-160. 10.1016/S0022-3999(02)00414-2.CrossRefPubMed
34.
go back to reference Mohs RC, Ashman TA, Jantzen K, Albert M, Brandt J, Gordon B, Rasmusson X, Grossman M, Jacobs D, Stern Y: A study of the efficacy of a comprehensive memory enhancement program in healthy elderly persons. Psychiatry Research. 1998, 77: 183-195. 10.1016/S0165-1781(98)00003-1.CrossRefPubMed Mohs RC, Ashman TA, Jantzen K, Albert M, Brandt J, Gordon B, Rasmusson X, Grossman M, Jacobs D, Stern Y: A study of the efficacy of a comprehensive memory enhancement program in healthy elderly persons. Psychiatry Research. 1998, 77: 183-195. 10.1016/S0165-1781(98)00003-1.CrossRefPubMed
35.
go back to reference Derwinger A, Neely AS, Backman L: Design your own memory strategies! Self-generated strategy training versus mnemonic training in old age: An 8-month follow-up. Neuropsychological Rehabilitation. 2005, 15: 37-54. 10.1080/09602010343000336.CrossRefPubMed Derwinger A, Neely AS, Backman L: Design your own memory strategies! Self-generated strategy training versus mnemonic training in old age: An 8-month follow-up. Neuropsychological Rehabilitation. 2005, 15: 37-54. 10.1080/09602010343000336.CrossRefPubMed
36.
go back to reference Fabre C, Chamari K, Mucci P, Masse-Biron J, Prefaut C: Improvement of cognitive function by mental and/or individualized aerobic training in healthy elderly subjects. International Journal of Sports Medicine. 2002, 23: 415-421. 10.1055/s-2002-33735.CrossRefPubMed Fabre C, Chamari K, Mucci P, Masse-Biron J, Prefaut C: Improvement of cognitive function by mental and/or individualized aerobic training in healthy elderly subjects. International Journal of Sports Medicine. 2002, 23: 415-421. 10.1055/s-2002-33735.CrossRefPubMed
37.
go back to reference Emery CF, Gatz M: Psychological and cognitive effects of an exercise program for community-residing older adults. Gerontologist. 1990, 30: 184-188.CrossRefPubMed Emery CF, Gatz M: Psychological and cognitive effects of an exercise program for community-residing older adults. Gerontologist. 1990, 30: 184-188.CrossRefPubMed
38.
go back to reference Williams P, Lord SR: Effects of group exercise on cognitive functioning and mood in older women. Australian and New Zealand Journal of Public Health. 1997, 21: 45-52.CrossRefPubMed Williams P, Lord SR: Effects of group exercise on cognitive functioning and mood in older women. Australian and New Zealand Journal of Public Health. 1997, 21: 45-52.CrossRefPubMed
39.
go back to reference Ball K, Berch DB, Helmers KF, Jobe JB, Leveck MD, Marsiske M, Morris JN, Rebok GW, Smith DM, Tennstedt SL, Unverzagt FW, Willis SL: Effects of cognitive training interventions with older adults: A randomized controlled trial. JAMA. 2002, 288: 2271-2281. 10.1001/jama.288.18.2271.CrossRefPubMedPubMedCentral Ball K, Berch DB, Helmers KF, Jobe JB, Leveck MD, Marsiske M, Morris JN, Rebok GW, Smith DM, Tennstedt SL, Unverzagt FW, Willis SL: Effects of cognitive training interventions with older adults: A randomized controlled trial. JAMA. 2002, 288: 2271-2281. 10.1001/jama.288.18.2271.CrossRefPubMedPubMedCentral
40.
go back to reference Kramer AF, Willis SL: Enhancing the cognitive vitality of older adults. Current Directions in Psychological Science. 2002, 11: 173-177. 10.1111/1467-8721.00194.CrossRef Kramer AF, Willis SL: Enhancing the cognitive vitality of older adults. Current Directions in Psychological Science. 2002, 11: 173-177. 10.1111/1467-8721.00194.CrossRef
41.
go back to reference Thompson G, Foth D: Cognitive-training programs for older adults: What are they and can they enhance mental fitness?. Educational Gerontology. 2005, 31: 603-626. 10.1080/03601270591003364.CrossRef Thompson G, Foth D: Cognitive-training programs for older adults: What are they and can they enhance mental fitness?. Educational Gerontology. 2005, 31: 603-626. 10.1080/03601270591003364.CrossRef
42.
go back to reference Hultsch DF, Hammer M, Small BJ: Age differences in cognitive performance in later life: Relationships to self-reported health and activity life style. Journal of Gerontology: Psychological Sciences. 1993, 48: 1-11.CrossRef Hultsch DF, Hammer M, Small BJ: Age differences in cognitive performance in later life: Relationships to self-reported health and activity life style. Journal of Gerontology: Psychological Sciences. 1993, 48: 1-11.CrossRef
43.
go back to reference Hultsch DF, Hertzog C, Small BJ, Dixon RA: Use it or lose it: Engaged lifestyle as a buffer of cognitive decline in aging?. Psychology and Aging. 1999, 14: 245-263. 10.1037/0882-7974.14.2.245.CrossRefPubMed Hultsch DF, Hertzog C, Small BJ, Dixon RA: Use it or lose it: Engaged lifestyle as a buffer of cognitive decline in aging?. Psychology and Aging. 1999, 14: 245-263. 10.1037/0882-7974.14.2.245.CrossRefPubMed
44.
go back to reference Newson RS, Kemps EB: General lifestyle activities as a predictor of current cognition and cognitive change in older adults: A cross-sectional and longitudinal examination. The Journals of Gerontology. 2005, 60B: 113-120.CrossRef Newson RS, Kemps EB: General lifestyle activities as a predictor of current cognition and cognitive change in older adults: A cross-sectional and longitudinal examination. The Journals of Gerontology. 2005, 60B: 113-120.CrossRef
45.
go back to reference Schooler C, Mulatu MS: The reciprocal effects of leisure time activities and intellectual functioning in older people: A longitudinal analysis. Psychology and Aging. 2001, 16: 466-482. 10.1037/0882-7974.16.3.466.CrossRefPubMed Schooler C, Mulatu MS: The reciprocal effects of leisure time activities and intellectual functioning in older people: A longitudinal analysis. Psychology and Aging. 2001, 16: 466-482. 10.1037/0882-7974.16.3.466.CrossRefPubMed
46.
go back to reference King AC, Rejeski WJ, Buchner DM: Physical activity interventions targeting older adults: A critical review and recommendations. American Journal of Preventive Medicine. 1998, 15: 316-332. 10.1016/S0749-3797(98)00085-3.CrossRefPubMed King AC, Rejeski WJ, Buchner DM: Physical activity interventions targeting older adults: A critical review and recommendations. American Journal of Preventive Medicine. 1998, 15: 316-332. 10.1016/S0749-3797(98)00085-3.CrossRefPubMed
47.
go back to reference Resnick B, Spellbring AM: Understanding what motivates older adults to exercise. Journal of Gerontological Nursing. 2000, 26: 34-42.CrossRefPubMed Resnick B, Spellbring AM: Understanding what motivates older adults to exercise. Journal of Gerontological Nursing. 2000, 26: 34-42.CrossRefPubMed
48.
go back to reference de Jager CA, Budge MM, Clarke R: Utility of TICS-M for the assessment of cognitive function in older adults. International Journal of Geriatric Psychiatry. 2003, 18: 318-324. 10.1002/gps.830.CrossRefPubMed de Jager CA, Budge MM, Clarke R: Utility of TICS-M for the assessment of cognitive function in older adults. International Journal of Geriatric Psychiatry. 2003, 18: 318-324. 10.1002/gps.830.CrossRefPubMed
49.
go back to reference Hassmen P, Ceci R, Backman L: Exercise for older women:A training method and its influences on physical and cognitive performance. European Journal of Applied Physiology. 1992, 64: 460-466. 10.1007/BF00625068.CrossRef Hassmen P, Ceci R, Backman L: Exercise for older women:A training method and its influences on physical and cognitive performance. European Journal of Applied Physiology. 1992, 64: 460-466. 10.1007/BF00625068.CrossRef
50.
go back to reference Beller EM, Gebski V, Keech AC: Randomisation in clinical trials. Medical Journal of Australia. 2002, 177: 565 -5567.PubMed Beller EM, Gebski V, Keech AC: Randomisation in clinical trials. Medical Journal of Australia. 2002, 177: 565 -5567.PubMed
51.
go back to reference ACSM: ACMS's guidelines for exercise testing and prescription. 2005, Baltimore, Lippincott, Williams & Wilkins, 7th ACSM: ACMS's guidelines for exercise testing and prescription. 2005, Baltimore, Lippincott, Williams & Wilkins, 7th
52.
go back to reference Borg G: Borg's Perceived Exertion and Pain Scales. 1998, Champaign, IL, Human Kinetics Borg G: Borg's Perceived Exertion and Pain Scales. 1998, Champaign, IL, Human Kinetics
53.
go back to reference Welsh KA, Breitner JCS, Magruder-Habib KM: Detection of dementia in the elderly using telephone screening of cognitive status. Neuropsychiatry, Neuropsychology, and Behavioral Neurology. 1993, 6: 103-110. Welsh KA, Breitner JCS, Magruder-Habib KM: Detection of dementia in the elderly using telephone screening of cognitive status. Neuropsychiatry, Neuropsychology, and Behavioral Neurology. 1993, 6: 103-110.
54.
go back to reference Moylan T, Das K, Gibb A, Hill A, Kane A, Lee C, Toye D, Wolstencroft K, Fail M, Stott DJ: Assessment of cognitive function in older hospital inpatients: Is the Telephone Interview for Cognitive Status (TICS-M) a useful alternative to the Mini Mental State Examination?. International Journal of Geriatric Psychiatry. 2004, 19: 1008-1009. 10.1002/gps.1181.CrossRefPubMed Moylan T, Das K, Gibb A, Hill A, Kane A, Lee C, Toye D, Wolstencroft K, Fail M, Stott DJ: Assessment of cognitive function in older hospital inpatients: Is the Telephone Interview for Cognitive Status (TICS-M) a useful alternative to the Mini Mental State Examination?. International Journal of Geriatric Psychiatry. 2004, 19: 1008-1009. 10.1002/gps.1181.CrossRefPubMed
55.
go back to reference Barber M, Stott DJ: Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects. International Journal of Geriatric Psychiatry. 2004, 19: 75-79. 10.1002/gps.1041.CrossRefPubMed Barber M, Stott DJ: Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects. International Journal of Geriatric Psychiatry. 2004, 19: 75-79. 10.1002/gps.1041.CrossRefPubMed
56.
go back to reference Delis DC, Kramer JH, Kaplan E, Ober BA: California Verbal Learning Test - Second Edition (CVLT-II). 2000, San Antonio, Texas, Psychological Corporation Delis DC, Kramer JH, Kaplan E, Ober BA: California Verbal Learning Test - Second Edition (CVLT-II). 2000, San Antonio, Texas, Psychological Corporation
57.
go back to reference Lezak MD, Howieson DB, Loring DW: Neuropsychological Assessment. 2004, Oxford, Oxford University Press, 4th Edition Lezak MD, Howieson DB, Loring DW: Neuropsychological Assessment. 2004, Oxford, Oxford University Press, 4th Edition
58.
go back to reference Wechsler D: Wechsler Memory Scale. Third edition manual. 1997, San Antonio, The Psychological Corporation Wechsler D: Wechsler Memory Scale. Third edition manual. 1997, San Antonio, The Psychological Corporation
59.
go back to reference Pachana N, Thompson LW, Marcopulous BA, Yoash-Gantz R: California Older Adult Stroop Test (COAST): Development of a stroop test adapted for geriatric populations. Clinical Gerontologist. 2004, 27: 3-22.CrossRef Pachana N, Thompson LW, Marcopulous BA, Yoash-Gantz R: California Older Adult Stroop Test (COAST): Development of a stroop test adapted for geriatric populations. Clinical Gerontologist. 2004, 27: 3-22.CrossRef
60.
go back to reference Delis DC, Kaplan E, Kramer JH: Delis-Kaplan Executive Function System. 2001, San Antonio, Psychological Corporation Delis DC, Kaplan E, Kramer JH: Delis-Kaplan Executive Function System. 2001, San Antonio, Psychological Corporation
61.
go back to reference Wechsler D: Wechsler Adult Intelligence Scale-III. 1997, San Antonio, The Psychological Corporation Wechsler D: Wechsler Adult Intelligence Scale-III. 1997, San Antonio, The Psychological Corporation
62.
go back to reference Smith A: Symbol Digit Modalities Test (SDMT). Manual (revised). 1982, Los Angeles, Western Psychological Services Smith A: Symbol Digit Modalities Test (SDMT). Manual (revised). 1982, Los Angeles, Western Psychological Services
63.
go back to reference Owsley C, Sloane M, McGwin GJ, Ball K: Timed instrumental activities of daily living tasks: Relationship to cognitive function and everyday performance assessments in older adults. Gerontology. 2002, 48: 254-265. 10.1159/000058360.CrossRefPubMed Owsley C, Sloane M, McGwin GJ, Ball K: Timed instrumental activities of daily living tasks: Relationship to cognitive function and everyday performance assessments in older adults. Gerontology. 2002, 48: 254-265. 10.1159/000058360.CrossRefPubMed
64.
go back to reference Spreen O, Strauss E: A compendium of neuropsychological tests: Administration, norms, and commentary. 1998, New York, Oxford University Press, 2nd Spreen O, Strauss E: A compendium of neuropsychological tests: Administration, norms, and commentary. 1998, New York, Oxford University Press, 2nd
65.
go back to reference Rikli RE, Jones CJ: Senior fitness test. 1997, Champaign, IL, Human Kinetics Rikli RE, Jones CJ: Senior fitness test. 1997, Champaign, IL, Human Kinetics
66.
go back to reference Crook TH, Feher EP, Larrabee GJ: Assessment of memory complaint in age-associated memory impairment: The MAC-Q. International Psychogeriatrics. 1992, 4: 165-176. 10.1017/S1041610292000991.CrossRefPubMed Crook TH, Feher EP, Larrabee GJ: Assessment of memory complaint in age-associated memory impairment: The MAC-Q. International Psychogeriatrics. 1992, 4: 165-176. 10.1017/S1041610292000991.CrossRefPubMed
67.
go back to reference McHorney CA, Ware JE, Raczek AE: The MOS 36-item short-form health survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care. 1993, 31: 247-263. 10.1097/00005650-199303000-00006.CrossRefPubMed McHorney CA, Ware JE, Raczek AE: The MOS 36-item short-form health survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care. 1993, 31: 247-263. 10.1097/00005650-199303000-00006.CrossRefPubMed
68.
go back to reference Ware JE, Snow K, Kosinski M, Gandek B: SF-36 Health Survey: Manual and interpretation guide. 2000, Lincoln, RI, Quality Metric Incorporated Ware JE, Snow K, Kosinski M, Gandek B: SF-36 Health Survey: Manual and interpretation guide. 2000, Lincoln, RI, Quality Metric Incorporated
69.
go back to reference Goldberg D, Bridges K, Duncan-Jones P, Grayson D: Detecting anxiety and depression in general medical settings. British Medical Journal. 1988, 297: 897-899.CrossRefPubMedPubMedCentral Goldberg D, Bridges K, Duncan-Jones P, Grayson D: Detecting anxiety and depression in general medical settings. British Medical Journal. 1988, 297: 897-899.CrossRefPubMedPubMedCentral
70.
go back to reference Pollock SE, Duffy ME: The Health-Related Hardiness Scale: Development and psychometric analysis. Nursing Research. 1990, 39: 218-222.PubMed Pollock SE, Duffy ME: The Health-Related Hardiness Scale: Development and psychometric analysis. Nursing Research. 1990, 39: 218-222.PubMed
71.
go back to reference MacDonald SWS, Hultsch DF, Dixon RA: Performance variability is related to change in cognition: Evidence from the Victoria Longitudinal Study. Psychology and Aging. 2003, 18: 510-523. 10.1037/0882-7974.18.3.510.CrossRefPubMed MacDonald SWS, Hultsch DF, Dixon RA: Performance variability is related to change in cognition: Evidence from the Victoria Longitudinal Study. Psychology and Aging. 2003, 18: 510-523. 10.1037/0882-7974.18.3.510.CrossRefPubMed
72.
go back to reference Jacobson NS, Follette WC, Revenstorf D: Psychotherapy outcome research: Methods for reporting variability and evaluating clinical significance. Behavior Therapy. 1984, 15: 336-352. 10.1016/S0005-7894(84)80002-7.CrossRef Jacobson NS, Follette WC, Revenstorf D: Psychotherapy outcome research: Methods for reporting variability and evaluating clinical significance. Behavior Therapy. 1984, 15: 336-352. 10.1016/S0005-7894(84)80002-7.CrossRef
73.
go back to reference Jacobson NS, Truax P: Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology. 1991, 59: 12-19. 10.1037/0022-006X.59.1.12.CrossRefPubMed Jacobson NS, Truax P: Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology. 1991, 59: 12-19. 10.1037/0022-006X.59.1.12.CrossRefPubMed
74.
go back to reference Bortz WM: Active Living, Cognitive Functioning, and Aging. 2006, Champaign, IL, Human Kinetics, 1: vii-viii. Foreword, Poon LW, Chodzko-Zajko W and Tomporowski PD, Aging, Exercise and Cognition Series, Poon LW, Spirduso WW, Chodzko-Zajko W. Bortz WM: Active Living, Cognitive Functioning, and Aging. 2006, Champaign, IL, Human Kinetics, 1: vii-viii. Foreword, Poon LW, Chodzko-Zajko W and Tomporowski PD, Aging, Exercise and Cognition Series, Poon LW, Spirduso WW, Chodzko-Zajko W.
Metadata
Title
Protocol for Fit Bodies, Fine Minds: a randomized controlled trial on the affect of exercise and cognitive training on cognitive functioning in older adults
Authors
Siobhan T O'Dwyer
Nicola W Burton
Nancy A Pachana
Wendy J Brown
Publication date
01-12-2007
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2007
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/1471-2318-7-23

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