Published in:
Open Access
01-12-2015 | Invited speaker presentation
Proteomic research of proteins involved in pain expression in an animal model of chronic pain
Authors:
Elisa Bellei, Stefania Bergamini, Emanuela Monari, Aurora Cuoghi, Michele Zoli, Aldo Tomasi, Maria Michela Cainazzo, Simona Guerzoni, Luigi Alberto Pini
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2015
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Excerpt
Pain is defined as an unpleasant sensory and emotional experience, associated with a real or potential tissue damage. Chronic pain (CP) can arise from tissue injuries or inflammation (inflammatory pain), or from lesions of the peripheral or central nervous system (neuropathic pain). The purpose of this study was to search proteins potentially involved in the expression or mediation of pain utilizing proteomic techniques, in an animal model of CP obtained by the ligation of the sciatic nerve. …