Proteomic approaches to early detection of breast cancer

Excerpt

The completion of the human genome as well as the explosion of novel technologies within genomics, proteomics and functional genomics promise to have a major impact on clinical practice, as these technologies are expected to accelerate the translation of basic discoveries to the clinical practice. In particular, proteomic technologies are expected to play a key role in the study and treatment of cancer as they provide invaluable resources to define and characterize regulatory and functional networks, to investigate the precise molecular defect in diseased tissues and biological fluids, and to develop specific reagents to precisely pinpoint a particular disease or stage of a disease. For drug discovery, proteomics assist with powerful tools for identifying new clinically relevant drug targets, and provide functional insight for drug development. …