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World Journal of Urology

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07-07-2023 | Prostatectomy | Original Article

Can salvage Retzius-sparing robotic-assisted radical prostatectomy improve continence outcomes? A systematic review and meta-analysis study

Authors: Igor Nunes-Silva, Alexandre Kyoshi Hidaka, Felipe Placco Araujo Glina, Renan Murata Hayashi, Sidney Glina

Published in: World Journal of Urology | Issue 9/2023

Abstract

Purpose

Salvage Radical Prostatectomy is challenging and associated with high rates of incontinence. The novel Retzius-sparing RARP (RS-RARP) approach has shown impressive high immediate and 1-year continence rates (> 90%) when applied as primary treatment. The purpose of this study is to evaluate the impact of salvage Retzius-sparing RARP (sRS-RARP) on continence outcomes in the salvage scenario.

Materials and methods

Using PRISMA guidelines, a systematic review and meta-analysis of articles was conducted on Medline through PubMed and on Cochrane through Central Register of Controlled Trials databases. Inclusion and exclusion criteria were used to select 17 retrospective cohort studies published until April 2023 about sRS-RARP and continence. Data were extracted independently by at least two authors. The International Prospective Register of Systematic Reviews (PROSPERO) was registered. Retrospective studies were subjected to a domain-based risk of bias assessment in accordance with the Newcastle–Ottawa quality assessment scale cohort studies (NOS). Prostate cancer patients were chosen from prospective nonrandomized or randomized sRS-RARP or sS-RARP studies that examined continence outcomes.

Results

Seventeen studies were included: 14 were retrospectives only and 3 described retrospective comparison cohorts (sRS-RARP vs sS-RARP). All the retrospective studies were of “fair” quality using the NOS. sRS-RARP may increase recovery of urinary continence after surgery compared to sS-RARP [OR 4.36, 95% CI 1.7–11.17; I² = 46.8%; studies = 4; participants = 87].

Conclusions

sRS-RARP approach has potential to improve continence outcomes in the salvage setting.

Patient summary

sRS-RARP approach has potential to positively impact continence function on patients who underwent salvage surgery.

Available only for authorised users

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Title: Can salvage Retzius-sparing robotic-assisted radical prostatectomy improve continence outcomes? A systematic review and meta-analysis study
Authors: Igor Nunes-Silva
Alexandre Kyoshi Hidaka
Felipe Placco Araujo Glina
Renan Murata Hayashi
Sidney Glina
Publication date: 07-07-2023
Publisher: Springer Berlin Heidelberg
Keywords: Prostatectomy
Prostatectomy
Prostate Cancer
Prostate Cancer
Published in: World Journal of Urology / Issue 9/2023
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-023-04505-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Can salvage Retzius-sparing robotic-assisted radical prostatectomy improve continence outcomes? A systematic review and meta-analysis study

Abstract

Purpose

Materials and methods

Results

Conclusions

Patient summary

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

Patient summary

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