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Open Access 01-12-2023 | Prostate Cancer | Original Research

Pentafecta outcomes of robotic laparoscopically assisted radical prostatectomy during the initial experience in a university hospital

Authors: Eduardo Tosetto Cachoeira, Artur de Oliveira Paludo, Pedro Glusman Knijnik, Pietro Waltrick Brum, Lucas Medeiros Burttet, Milton Berger, Brasil Silva Neto

Published in: African Journal of Urology | Issue 1/2023

Abstract

Background

Robotic laparoscopically assisted radical prostatectomy (RARP) is an option for the treatment of localized prostate cancer. The objective of the present study was to evaluate the pentafecta outcomes (biochemical recurrence, continence, potency, surgical complications and surgical margins) in patients undergoing RARP during the initial experience in a university hospital.

Methods

This is a retrospective study of patients who had RARP for localized prostate adenocarcinoma at a university hospital from August 2013 to October 2019 to evaluate pentafecta outcomes (biochemical recurrence, continence, potency, surgical complications and surgical margins). Data were collected and stored via Microsoft Office Excel program and analyzed using SPSS Software, version 20.0.

Results

One hundred and sixty-three RARP were performed, the mean age is 64.16 ± 6.54 years, PSA 6.20 (IQR = 4.91–8.95) ng/dl, BMI 27.14 (IQR = 24.22–29.26) kg/m², D’Amico risk classification was 35 (22.3%) low risk, 81 (51.6%) intermediate risk and 41 (26.1%) high risk. One hundred and fifty-four patients entered the analysis of pentafecta with a rate of 38.3% reaching this outcome. Complications: Twenty-three (14.1%) patients had minor complications (Clavien I and II) and eight patients had major complications (Clavien IIIa, IIIb and IVa). Surgical margins were negative in 69.9% of patients. The biochemical recurrence-free rate was 89.5%. The overall continence rate was 93.5%, and the potency rate was 63.5%. Multivariate analysis showed that T2 patients are 2.7 times more likely to achieve pentafecta outcome than patients ≥ T3 (p < 0.05), while younger age and lower BMI data were found as a protective factor with RR of 0.95 and 0.94, respectively.

Conclusions

Preliminary pentafecta outcome of RARP in this university hospital is promising.

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Title: Pentafecta outcomes of robotic laparoscopically assisted radical prostatectomy during the initial experience in a university hospital
Authors: Eduardo Tosetto Cachoeira
Artur de Oliveira Paludo
Pedro Glusman Knijnik
Pietro Waltrick Brum
Lucas Medeiros Burttet
Milton Berger
Brasil Silva Neto
Publication date: 01-12-2023
Publisher: Springer Berlin Heidelberg
Keywords: Prostate Cancer
Prostate Cancer
Prostatectomy
Prostatectomy
Published in: African Journal of Urology / Issue 1/2023
Print ISSN: 1110-5704
Electronic ISSN: 1961-9987
DOI: https://doi.org/10.1186/s12301-023-00338-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pentafecta outcomes of robotic laparoscopically assisted radical prostatectomy during the initial experience in a university hospital

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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