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15-09-2022 | Prostate Cancer | Editorial Comment

Should we combine systematic with MRI-targeted biopsy? Implications for the management of patients with prostate cancer

Authors: Giorgio Gandaglia, Gianluca Giannarini, Armando Stabile, Francesco Montorsi, Alberto Briganti

Published in: European Radiology | Issue 11/2022

Excerpt

In the current issue of European Radiology, Deniffel and colleagues analysed a large cohort of men with a clinical suspicion of prostate cancer (PCa) who underwent combined MRI-targeted plus systematic biopsy performed by seven experienced radiologists at a high-volume tertiary referral centre [1]. The authors demonstrated that the addition of systematic biopsy in men with elevated PSA levels and at least one PI-RADS score 3 to 5 lesion on multiparametric MRI (mpMRI) allowed for the identification of only 6% additional clinically significant PCa (csPCa) cases, defined as International Society of Urological Pathology Grade Group ≥ 2. In this small proportion of patients, the diagnosis of csPCa would have been missed by MRI-targeted biopsy alone. …

Deniffel D, Perlis N, Ghai S et al (2022) Prostate biopsy in the era of MRI-targeting: towards a judicious use of additional systematic biopsy. Eur Radiol. https://doi.org/10.1007/s00330-022-08822-3

Rouvière O, Puech P, Renard-Penna R et al (2019) Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study. Lancet Oncol 20:100–109CrossRef

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Gandaglia G, Ploussard G, Valerio M et al (2020) Prognostic implications of multiparametric magnetic resonance imaging and concomitant systematic biopsy in predicting biochemical recurrence after radical prostatectomy in prostate cancer patients diagnosed with magnetic resonance imaging–targeted biopsy. Eur Urol Oncol 3:739–747CrossRef

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Title: Should we combine systematic with MRI-targeted biopsy? Implications for the management of patients with prostate cancer
Authors: Giorgio Gandaglia
Gianluca Giannarini
Armando Stabile
Francesco Montorsi
Alberto Briganti
Publication date: 15-09-2022
Publisher: Springer Berlin Heidelberg
Keywords: Prostate Cancer
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Prostate Cancer
Prostatectomy
Prostatectomy
Published in: European Radiology / Issue 11/2022
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-022-09096-5

At a glance: The STEP trials

Springer Medicine

Should we combine systematic with MRI-targeted biopsy? Implications for the management of patients with prostate cancer

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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