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World Journal of Urology

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01-04-2014 | Original Article

Prostate cancer detection with real-time elastography using a bi-plane transducer: comparison with step section radical prostatectomy pathology

Authors: Yunkai Zhu, Yaqing Chen, Tingyue Qi, Jun Jiang, Jun Qi, Yongjiang Yu, Xiaohong Yao, Wenbin Guan

Published in: World Journal of Urology | Issue 2/2014

Abstract

Purpose

To evaluate elastography using a bi-plane transducer for localizing prostate cancer (PCa) in patients scheduled for radical prostatectomy (RP), in comparison with step section pathological analysis.

Methods

Fifty-six consecutive PCa patients underwent real-time elastography examination with a bi-plane transducer before RP. Transverse elastographic images were obtained from the apex to the base by slightly compressing and releasing the prostate tissue using the probe. The diagnostic performance of elastography was evaluated in correlation with step section RP histopathology.

Results

In 56 PCa patients, gray-scale ultrasonography detected at least one lesion in 36 patients, whereas elastography detected at least one lesion in 53 patients (P = 0.001). The overall sensitivity, specificity and accuracy of elastography in depicting tumor lesions were 67.6, 89.5 and 82.7 %, respectively. The detection rate of a PCa lesion with elastography was best in the left posterior region, followed by the right posterior region. Elastography was more sensitive in detecting PCa lesions with higher Gleason scores, diameter >5 mm and extracapsular extension.

Conclusions

The additional use of elastography with the bi-plane transducer can improve PCa detection rate by providing more information about tissue stiffness within the prostate gland.

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Title: Prostate cancer detection with real-time elastography using a bi-plane transducer: comparison with step section radical prostatectomy pathology
Authors: Yunkai Zhu
Yaqing Chen
Tingyue Qi
Jun Jiang
Jun Qi
Yongjiang Yu
Xiaohong Yao
Wenbin Guan
Publication date: 01-04-2014
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 2/2014
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-012-0922-1

2024 ASCO Annual Meeting

Springer Medicine

Prostate cancer detection with real-time elastography using a bi-plane transducer: comparison with step section radical prostatectomy pathology

Abstract

Purpose

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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