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Archives of Gynecology and Obstetrics

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01-05-2013 | Reproductive Medicine

Prostaglandin E₂ alteration in contraceptive consumers: as a risk factor for inflammatory diseases

Authors: Maryam Sanjary Pour, Soudabeh Fallah, Azra Rabbani Chadegani

Published in: Archives of Gynecology and Obstetrics | Issue 5/2013

Abstract

Purpose

The aim of this study was to evaluate the effect of oral combined contraceptive pills on Prostaglandin E₂ levels and lipid profiles.

Methods

The enzyme-linked immune absorbent assay method and spectrophotometric assay were used for the evaluation of PGE₂ levels and lipid profiles, respectively, in 50 healthy women with normal menstrual cycles who served as the control group and 50 women taking contraceptive pill.

Results

The data obtained for serum Prostaglandin E₂, LDL-C, and cholesterol concentrations in contraceptive pill consumers were significantly upper (P = 0.04, 0.002, and 0.05, respectively) than control group. The age of contraceptive pill consumption and the duration of pill intake beyond 36 months had no significant effect on the prostaglandin E₂ concentration.

Conclusion

It is suggested that the increase of Prostaglandin E₂ and atherogenic lipid levels may be related to their probable effects in response to various pathological and physiological properties of COCs.

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Title: Prostaglandin E2 alteration in contraceptive consumers: as a risk factor for inflammatory diseases
Authors: Maryam Sanjary Pour
Soudabeh Fallah
Azra Rabbani Chadegani
Publication date: 01-05-2013
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2013
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-012-2661-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prostaglandin E₂ alteration in contraceptive consumers: as a risk factor for inflammatory diseases

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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