Published in:
Open Access
01-12-2011 | Oral presentation
Prospective comparison on cardiac iron by MR in thalassemia major patients treated with combination deferipron-desferrioxamine versus deferipron and desferrioxamine in monoterapy
Authors:
Alessia Pepe, Antonella Meloni, Giuseppe Rossi, Maria Chiara Dell'Amico, Marcello Capra, Vincenzo Caruso, Lorella Pitrolo, Michele Centra, Pasquale Pepe, Eliana Cracolici, Paolo Ricchi, Massimo Lombardi
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2011
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Excerpt
Combination therapy with deferipron and desferrioxamine (DFP+DFO) seems more effective than DFP and DFO in monotherapy in removing myocardial iron. However, no data are available in literature about prospective comparisons on cardiac iron and function in TM patients treated with DFP+DFO versus DFP and DFO in monotherapy. Aim: The aim of this multi-centre study was to assess prospectively in a large clinical setting the efficacy of the DFP+DFO versus DFP and DFO in TM patients by quantitative MR. …