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European Radiology
Published in: European Radiology 10/2008

01-10-2008 | Hepatobiliary-Pancreas

Prospective comparison of high- and low-spatial-resolution dynamic MR imaging with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinoma

Authors: Masakatsu Tsurusaki, Richard C. Semelka, Kensuke Uotani, Koji Sugimoto, Masahiko Fujii, Kazuro Sugimura

Published in: European Radiology | Issue 10/2008

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Abstract

The purpose of this study was to prospectively evaluate the efficacy of high-spatial-resolution dynamic MRI using sensitivity encoding (SENSE) in detection of hypervascular hepatocellular carcinoma (HCC). Thirty-five patients were included in this prospectively planned study, and 25 patients with 31 HCCs were assigned into three groups and underwent the following sequences: group A (n = 11): three-dimensional fast-gradient-echo (3D-FGE) high-spatial-resolution dynamic MRI (HR-MRI) with SENSE; group B (n = 10): 3D-FGE low-spatial-resolution dynamic MRI (LR-MRI) with SENSE; and group C (n = 14): 3D-FGE/LR-MRI without SENSE. For the quantitative analysis, the lesion-to-liver contrast-to-noise ratio (CNR) between the liver and HCCs was measured. For the qualitative analysis, overall image quality for each group was evaluated with a five-point scale analysis. The sensitivities for detection of HCCs were evaluated. The overall image quality in group A was significantly greater than both groups B and C (P < 0.01). The sensitivity of lesion detection on HAP was not significantly higher in group A (100%) than group C (69.2%; P > 0.05). In our pilot study on a small number of patients, image quality in HR-MRI with SENSE was superior to LR-MRI. A high detection rate was seen with HR-MRI with SENSE in the patients with hypervascular HCCs.
Literature
1.
Yamashita Y, Mitsuzaki K, Yi T, Ogata I, Nishiharu T, Urata J, Takahashi M (1996) Small hepatocellular carcinoma in patients with chronic liver damage: prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver. Radiology 200:79–84PubMed
2.
Peterson MS, Baron RL, Murakami T (1996) Hepatic malignancies: usefulness of acquisition of multiple arterial and portal venous phase imaging at dynamic gadolinium-enhanced MR imaging. Radiology 201:337–345PubMed
3.
Yoshimitsu K, Honda H, Jimi M, Kuroiwa T, Irie H, Aibe H, Shinozaki K, Asayama Y, Shimada M, Masuda K (2001) Correlation of three-dimensional gradient echo dynamic MR imaging with CT during hepatic arteriography in patients with hypervascular hepatocellular carcinomas: preliminary clinical experience. J Magn Reson Imaging 13:258–262PubMedCrossRef
4.
Hecht EM, Holland AE, Israel GM, Hahn WY, Kim DC, West AB, Babb JS, Taouli B, Lee VS, Krinsky GA (2006) Hepatocellular carcinoma in the cirrhotic liver: gadolinium-enhanced 3D T1-weighted MR imaging as a stand-alone sequence for diagnosis. Radiology 239:438–447PubMedCrossRef
5.
Kanematsu M, Hoshi H, Murakami T, Itoh K, Hori M, Kondo H, Nakamura H (1999) Detection of hepatocellular carcinoma: comparison of low- and high-spatial resolution dynamic MR images. AJR Am J Roentgenol 173:1207–1212PubMed
6.
Fujita T, Ito K, Honjo K, Okazaki H, Matsumoto T, Matsunaga N (1999) Detection of hepatocellular carcinoma: comparison of T2-weighted breath-hold fast spin-echo sequences and high-resolution dynamic MR imaging with a phased-array body coil. J Magn Reson Imaging 9:274–279PubMedCrossRef
7.
Ohtomo K, Matsuoka Y, Abe O, Okada M, Amo K, Minami M, Kawauchi N, Sasaki Y (1997) High-resolution MR imaging evaluation of hepatocellular carcinoma. Abdom Imaging 22:182–186PubMedCrossRef
8.
Fujita T, Honjo K, Ito K, Matsumoto T, Matsunaga N, Hamm B (1997) High-resolution dynamic MR imaging of hepatocellular carcinoma with a phased-array body coil. Radiographics 17:315–31PubMed
9.
Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) SENSE: sensitivity encoding for fast MRI. Magn Reson Med 42:952–962PubMedCrossRef
10.
Golay X, Pruessmann KP, Weiger M, Crelier GR, Folkers PJ, Kollias SS, Boesiger P (2000) PRESTO-SENSE: an ultrafast whole-brain functional MRI technique. Magn Reson Med 43:779–786PubMedCrossRef
11.
Weiger M, Pruessmann KP, Boesiger P (2000) Cardiac real-time imaging using SENSE. Magn Reson Med 43:177–184PubMedCrossRef
12.
Weiger M, Pruessmann KP, Kassner A, Roditi G, Lawton T, Reid A, Boesiger P (2000) Contrast-enhanced 3D MRA using SENSE. J Magn Reson Imaging 12:671–677PubMedCrossRef
13.
Bammer R, Keeling SL, Augustin M, Pruessmann KP, Wolf R, Stollberger R, Hartung HP, Fazekas F (2001) Improved diffusion-weighted single-shot echo-planar imaging (EPI) in stroke using sensitivity encoding (SENSE). Magn Reson Med 46:548–554PubMedCrossRef
14.
Ohno Y, Kawamitsu H, Higashino T, Takenaka D, Watanabe H, van Cauteren M, Fujii M, Hatabu H, Sugimura K (2003) Time-resolved contrast-enhanced pulmonary MR angiography using sensitivity encoding (SENSE). J Magn Reson Imaging 17:330–336PubMedCrossRef
15.
Yoshioka H, Takahashi N, Yamaguchi M, Lou D, Saida Y, Itai Y (2002) Double arterial phase dynamic MRI with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinomas. J Magn Reson Imaging 16:259–266PubMedCrossRef
16.
Takahashi N, Yoshioka H, Yamaguchi M, Saida Y, Itai Y (2003) Accelerated dynamic MR imaging with a parallel imaging technique for hypervascular hepatocellular carcinomas: usefulness of a test bolus in examination and subtraction imaging. J Magn Reson Imaging 18:80–89PubMedCrossRef
17.
Mori K, Yoshioka H, Takahashi N, Yamaguchi M, Ueno T, Yamaki T, Saida Y (2005) Triple arterial phase dynamic MRI with sensitivity encoding for hypervascular hepatocellular carcinoma: comparison of the diagnostic accuracy among the early, middle, late, and whole triple arterial phase imaging. AJR Am J Roentgenol 184:63–9PubMed
18.
Kim YK, Kim CS, Kwak HS, Lee JM (2004) Three-dimensional dynamic liver MR imaging using sensitivity encoding for detection of hepatocellular carcinomas: comparison with superparamagnetic iron oxide-enhanced MR imaging. J Magn Reson Imaging 20:826–37PubMedCrossRef
19.
Zech CJ, Herrmann KA, Huber A, Dietrich O, Stemmer A, Herzog P, Reiser MF, Schoenberg SO (2004) High-resolution MR-imaging of the liver with T2-weighted sequences using integrated parallel imaging: comparison of prospective motion correction and respiratory triggering. J Magn Reson Imaging 20:443–50PubMedCrossRef
20.
Tanaka O, Ito H, Yamada K, Kubota T, Kizu O, Kato T, Yamagami T, Nishimura T (2005) Higher lesion conspicuity for SENSE dynamic MRI in detecting hypervascular hepatocellular carcinoma: analysis through the measurements of liver SNR and lesion-liver CNR comparison with conventional dynamic MRI. Eur Radiol 15:2427–34PubMedCrossRef
21.
Rofsky NM, Lee VS, Laub G, Pollack MA, Krinsky GA, Thomasson D, Ambrosino MM, Weinreb JC (1999) Abdominal MR imaging with a volumetric interpolated breath-hold examination. Radiology 212:876–884PubMed
22.
Kadoya M, Matsui O, Takashima T, Nonomura A (1992) Hepatocellular carcinoma: correlation of MR imaging and histopathologic findings. Radiology 183:819–825PubMed
Metadata
Title
Prospective comparison of high- and low-spatial-resolution dynamic MR imaging with sensitivity encoding (SENSE) for hypervascular hepatocellular carcinoma
Authors
Masakatsu Tsurusaki
Richard C. Semelka
Kensuke Uotani
Koji Sugimoto
Masahiko Fujii
Kazuro Sugimura
Publication date
01-10-2008
Publisher
Springer-Verlag
Published in
European Radiology / Issue 10/2008
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-008-1003-0

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