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01-02-2017 | Original Article

Prospective assessment of perioperative course in 2648 patients after surgical treatment of benign prostatic obstruction

Authors: Thorsten Bach, Felix Wölbling, Andreas J. Gross, C. Netsch, S. Tauber, Tobias Pottek, Christian Wülfing, Claus Brunken

Published in: World Journal of Urology | Issue 2/2017

Abstract

Purpose

TUR-prostate (TUR-P) is considered the reference method for surgical treatment of benign prostatic obstruction (BPO); Greenlight laser photoselective vaporization (PVP) and thulium laser vapoenucleation (ThuVEP) have also been established as treatments of BPO. Objective of this prospective observation was to compare a large numbers of patients treated in everyday routine.

Methods

This prospective multicentre data collection assesses morbidity and perioperative course of consecutive men treated with BPO-related transurethral surgery between 2011 and 2014 in a German metropolis area with TUR-P, PVP or ThuVEP.

Results

Two thousand six hundred and forty-eight patients have been treated in the time period. All treatment options achieved immediate improvement of voiding parameters. Multivariate analyses proved shorter hospital stay after laser treatments as compared to resection (p < 0.001). In terms of hospital stay, the advantage of ThuVEP compared to TUR-P increased with prostate volume (p < 0.001). Patients with ongoing anticoagulation or bridging had prolonged hospital stay (p < 0.001). Overall adverse events were least frequent in PVP (p 0.016), as were Clavien 3b events (p < 0.001).

Conclusions

Surgical treatment of BPO is effective and safe independent of the surgical procedure. Volume reduction is most effective in ThuVEP; PVP has the lowest rate of severe complications. Laser treatment is associated with shorter hospital stay. Surgery under ongoing anticoagulation prolonged the post-operative hospital stay.

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Title: Prospective assessment of perioperative course in 2648 patients after surgical treatment of benign prostatic obstruction
Authors: Thorsten Bach
Felix Wölbling
Andreas J. Gross
C. Netsch
S. Tauber
Tobias Pottek
Christian Wülfing
Claus Brunken
Publication date: 01-02-2017
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 2/2017
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-016-1866-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Prospective assessment of perioperative course in 2648 patients after surgical treatment of benign prostatic obstruction

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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