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Open Access 01-12-2018 | Short report

Prolonged migraine aura: new insights from a prospective diary-aided study

Authors: Michele Viana, Grazia Sances, Mattias Linde, Giuseppe Nappi, Farihah Khaliq, Peter J. Goadsby, Cristina Tassorelli

Published in: The Journal of Headache and Pain | Issue 1/2018

Abstract

Background

There is limited literature on prolonged aura (PA - defined as an aura including at least one symptom for > 1 h and < 7d), and there are no prospective studies.

The aim of this study is to characterize prospectively the phenotype and prevalence of PA.

Findings

Two hundred and twenty-four patients suffering from migraine with aura were recruited from the Headache Centers of Pavia and Trondheim. Patients prospectively described, on an ad hoc diary, each aura symptom (AS), the duration of AS and headache, and headache features. Seventy-two patients recorded three consecutive auras in their diaries. 19 (26.4%) of patients suffered at least one PA. Out of 216 recorded auras, 38 (17.6%) were PAs. We compared PAs with non-PAs with respect to 20 features; PAs were characterized by a higher number of non-visual symptoms (non-VS) (p < 0.001). No other differences were found. We obtained similar results when we compared auras with at least one symptom with a duration of > 2 h (n = 23) or > 4 h (n = 14) with the the others (n = 193 and n = 202 respectively).

Conclusion

PAs are quite common. They do not differ from the other auras (even when their duration extends to 2 and/or 4 h) with the exception of a higher number of non-VS.

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Title: Prolonged migraine aura: new insights from a prospective diary-aided study
Authors: Michele Viana
Grazia Sances
Mattias Linde
Giuseppe Nappi
Farihah Khaliq
Peter J. Goadsby
Cristina Tassorelli
Publication date: 01-12-2018
Publisher: Springer Milan
Published in: The Journal of Headache and Pain / Issue 1/2018
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI: https://doi.org/10.1186/s10194-018-0910-y

At a glance: The STEP trials

Springer Medicine

Prolonged migraine aura: new insights from a prospective diary-aided study

Abstract

Background

Findings

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Findings

Conclusion

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