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Acta Neurologica Belgica
Published in: Acta Neurologica Belgica 3/2016

01-09-2016 | Letter to the Editor

Progressive multifocal leukoencephalopathy mimicking glioma in a patient with idiopathic CD4 lymphocytopenia

Authors: Harsh V. Gupta, Murat Gokden, Raghu H. Ramakrishnaiah, Robert L. Archer

Published in: Acta Neurologica Belgica | Issue 3/2016

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Excerpt

Progressive multifocal leukoencephalopathy (PML) was described for the first time in 1958 by Astrom et al. as a demyelinating disease in patients with leukemia and lymphoma. A viral etiology for this condition was suggested as the oligodendrocytes contained inclusion bodies [1]. MRI features described in classical PML include hyperintense lesions on T2-weighted and FLAIR sequence which are asymmetric, devoid of contrast enhancement or mass effect, and relatively spare periventricular white matter [2]. We are reporting a case of PML in a patient with ICL (idiopathic CD4 lymphopenia) in which MRI brain showed punctate contrast enhancement, gyral swelling, and a pattern on MR spectroscopy concerning for a glioma. …
Literature
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Metadata
Title
Progressive multifocal leukoencephalopathy mimicking glioma in a patient with idiopathic CD4 lymphocytopenia
Authors
Harsh V. Gupta
Murat Gokden
Raghu H. Ramakrishnaiah
Robert L. Archer
Publication date
01-09-2016
Publisher
Springer International Publishing
Published in
Acta Neurologica Belgica / Issue 3/2016
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-015-0532-y

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