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Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 4/2009

01-08-2009 | Original Article

Prognostic validation of an algorithm to convert myocardial perfusion SPECT imaging data from a 12-segment model to a 17-segment model

Authors: Michael Salerno, MD, PhD, Laine Elliot, MS, Linda K. Shaw, MS, Jonathan P. Piccini, MD, Robert Pagnanelli, CNMT, Salvador Borges-Neto, MD

Published in: Journal of Nuclear Cardiology | Issue 4/2009

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Abstract

Background

A 17-segment model has become the standard for interpreting myocardial perfusion single-photon emission computed tomography (SPECT). Methods for converting pre-existing databases from 12-segment models to the 17-segment model are needed for ongoing prognostic studies.

Methods and Results

To develop the conversion algorithm, 150 consecutive SPECT studies (82 abnormal) were read by both a 12-segment and the standard 17-segment models. Summed stress scores (SSSs) were calculated from a 17-segment model derived from the 12-segment data and compared to those of the standard 17-segment model. The effect of the conversion algorithm on prognostic data derived from the 12-segment model was evaluated in 25,876 patients from the Duke Nuclear Cardiology Database, including a sample of 3,205 patients with known covariates for adjusted analysis. The derived 17-segment SSS from the 12-segment model was highly correlated (R = 0.99) to the SSS from the standard 17-segment model. In both unadjusted and adjusted analysis, there was no difference in the prognostic information.

Conclusions

An algorithm for conversion of 12-segment perfusion scores to 17-segment scores has been developed which is highly correlated to visual interpretation by the 17-segment model with nearly identical prognostic information.
Appendix
Available only for authorised users
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Metadata
Title
Prognostic validation of an algorithm to convert myocardial perfusion SPECT imaging data from a 12-segment model to a 17-segment model
Authors
Michael Salerno, MD, PhD
Laine Elliot, MS
Linda K. Shaw, MS
Jonathan P. Piccini, MD
Robert Pagnanelli, CNMT
Salvador Borges-Neto, MD
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Journal of Nuclear Cardiology / Issue 4/2009
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-009-9103-z

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