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01-04-2010 | Review Article

Prognostic role of myocardial single photon emission computed tomography in the elderly

Authors: Pasquale Perrone-Filardi, MD, PhD, Pierluigi Costanzo, MD, Santo Dellegrottaglie, MD, PhD, Paola Gargiulo, MD, Donatella Ruggiero, MD, Gianluigi Savarese, MD, Antonio Parente, MD, Carmen D’Amore, MD, Alberto Cuocolo, MD, Massimo Chiariello, MD

Published in: Journal of Nuclear Cardiology | Issue 2/2010

Abstract

The increase in average life expectancy will move the burden of coronary artery disease (CAD) to older patients. Myocardial perfusion imaging by single photon emission computed tomography (SPECT) has been extensively validated for diagnosis and prognostic evaluation in large population series. Yet, its use is usually limited in elderly patients in whom, despite increased absolute cardiovascular risk, diagnostic and therapeutic work-up is often underperformed. American College of Cardiology/American Heart Association guidelines recommend exercise ECG testing as the initial noninvasive method for assessment of CAD in patients with a normal or near-normal resting ECG, regardless of age. However, a considerable proportion of elderly patients is unable to reach an adequate workload during the exercise test and the majority of those undergoing for standard exercise treadmill score are classified as intermediate risk. In elderly patients, SPECT imaging may provide valuable diagnostic and prognostic information for clinical management. In particular, normal or near normal SPECT identifies elderly patients at low risk of major adverse cardiac events at the short-term follow-up.

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Title: Prognostic role of myocardial single photon emission computed tomography in the elderly
Authors: Pasquale Perrone-Filardi, MD, PhD
Pierluigi Costanzo, MD
Santo Dellegrottaglie, MD, PhD
Paola Gargiulo, MD
Donatella Ruggiero, MD
Gianluigi Savarese, MD
Antonio Parente, MD
Carmen D’Amore, MD
Alberto Cuocolo, MD
Massimo Chiariello, MD
Publication date: 01-04-2010
Publisher: Springer-Verlag
Published in: Journal of Nuclear Cardiology / Issue 2/2010
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-009-9182-x

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Prognostic role of myocardial single photon emission computed tomography in the elderly

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