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Open Access 01-12-2013 | Case report

Profound hyperacute cardiac allograft rejection rescue with biventricular mechanical circulatory support and plasmapheresis, intravenous immunoglobulin, and rituximab therapy

Authors: David J Kaczorowski, Jashodeep Datta, Malek Kamoun, Daniel L Dries, Y Joseph Woo

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Abstract

Hyperacute rejection is a rare but potentially catastrophic complication after cardiac transplantation. We describe an unusual case of hyperacute rejection due to preformed anti-donor antibodies despite a negative preoperative panel-reactive antibody (PRA) screen. An excellent outcome was achieved in this case and our strategy involving the use of CentriMag ventricular assist devices (VADs) for biventricular support during treatment with rituximab, intravenous immunoglobulin (IVIG), and plasmapheresis is illustrated.

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Title: Profound hyperacute cardiac allograft rejection rescue with biventricular mechanical circulatory support and plasmapheresis, intravenous immunoglobulin, and rituximab therapy
Authors: David J Kaczorowski
Jashodeep Datta
Malek Kamoun
Daniel L Dries
Y Joseph Woo
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-8-48

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Profound hyperacute cardiac allograft rejection rescue with biventricular mechanical circulatory support and plasmapheresis, intravenous immunoglobulin, and rituximab therapy

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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