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01-01-2009 | Letter to the Editor

Probiotics and acute pancreatitis need a long way to go

Authors: Kehu Yang, Shaoliang Sun, Jinhui Tian

Published in: Langenbeck's Archives of Surgery | Issue 1/2009

Excerpt

Thanks for the comment from Besselink et al. Their randomized trial of probiotic prophylaxis in patients with predicted severe acute pancreatitis was a respected clinical trial, although the results were opposite to expectations. The results raised several questions. In order to ascertain the effect of probiotics in severe acute pancreatitis, we did a meta-analysis and got the conclusion from the current evidences: probiotics and acute pancreatitis need a long way to go! …

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Besselink MG, Van Santvoort HC, Buskens E et al (2008) Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet 371:651–659 doi:10.1016/S0140-6736(08)60207-X PubMedCrossRef

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Olah A, Belagyi T, Issekutz A et al (2002) Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis. Br J Surg 89:1103–1107 doi:10.1046/j.1365-2168.2002.02189.x PubMedCrossRef

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Title: Probiotics and acute pancreatitis need a long way to go
Authors: Kehu Yang
Shaoliang Sun
Jinhui Tian
Publication date: 01-01-2009
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 1/2009
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-008-0420-5

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Probiotics and acute pancreatitis need a long way to go

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