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Published in: Journal of Neuro-Oncology 1/2011

01-01-2011 | Case Report

Primary skull-based yolk-sac tumour: case report and review of central nervous system germ cell tumours

Authors: Raman Verma, Shawn Malone, Christina Canil, Gerard Jansen, Howard Lesiuk

Published in: Journal of Neuro-Oncology | Issue 1/2011

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Abstract

Primary intra-cranial germ-cell tumours (GCT) are rare and it is important to differentiate them histologically as their prognosis and treatment is quite different. Moreover, highly malignant non-germinomatous GCT (NG GCT) comprise a small portion of these tumours with limited data available on appropriate treatment approaches. We present the case of a 22-year-old male with a unique primary skull-based yolk-sac subtype NG GCT with a literature review of current treatment options. To our knowledge, there have not been any previously published reports of a primary yolk-sac tumour arising from the petrous apex.
Literature
1.
go back to reference Drappatz J, Loeffler J (2006) Primary intracranial germ cell tumors. In: Raghaven D et al (eds) Textbook of uncommon cancer, 3rd edn. Wiley, England, pp 649–656CrossRef Drappatz J, Loeffler J (2006) Primary intracranial germ cell tumors. In: Raghaven D et al (eds) Textbook of uncommon cancer, 3rd edn. Wiley, England, pp 649–656CrossRef
2.
go back to reference Jennings M, Gelman R, Hochberg F (1985) Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 63:155–167CrossRefPubMed Jennings M, Gelman R, Hochberg F (1985) Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 63:155–167CrossRefPubMed
3.
go back to reference Louis D, Ohgaki H et al (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97–109CrossRefPubMed Louis D, Ohgaki H et al (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97–109CrossRefPubMed
4.
go back to reference Packer R, Cohen B, Coney K (2000) Intracranial germ cell tumors. The Oncologist 5:312–320PubMed Packer R, Cohen B, Coney K (2000) Intracranial germ cell tumors. The Oncologist 5:312–320PubMed
5.
go back to reference Matsutani M, Sano K et al (1997) Primary intracranial germ-cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg 86:446–455CrossRefPubMed Matsutani M, Sano K et al (1997) Primary intracranial germ-cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg 86:446–455CrossRefPubMed
6.
go back to reference Cheon H, Jung S et al (2006) Primary endodermal sinus tumor of the cerebellar hemisphere: a case report with review of the literature. J Neurooncol 77:173–176CrossRefPubMed Cheon H, Jung S et al (2006) Primary endodermal sinus tumor of the cerebellar hemisphere: a case report with review of the literature. J Neurooncol 77:173–176CrossRefPubMed
7.
go back to reference Kan P, Gottfried O et al (2006) Primary spinal yolk-sac tumor with brain metastasis: case report and review of the literature. J Neurooncol 78:249–253CrossRefPubMed Kan P, Gottfried O et al (2006) Primary spinal yolk-sac tumor with brain metastasis: case report and review of the literature. J Neurooncol 78:249–253CrossRefPubMed
8.
go back to reference Mishra A, El-Naggar A et al (2008) Endodermal sinus tumor of the paranasal sinuses. Head Neck 30:539–543 Mishra A, El-Naggar A et al (2008) Endodermal sinus tumor of the paranasal sinuses. Head Neck 30:539–543
9.
go back to reference Sawamura Y, Ikeda J et al (1998) Germ cell tumours of the central nervous system: Treatment consideration based on 111 cases and their long-term clinical outcomes. Eur J Cancer 34(1):104–110CrossRefPubMed Sawamura Y, Ikeda J et al (1998) Germ cell tumours of the central nervous system: Treatment consideration based on 111 cases and their long-term clinical outcomes. Eur J Cancer 34(1):104–110CrossRefPubMed
10.
go back to reference Matsutani M (2004) Clinical management of primary central nervous system germ cell tumors. Semin Oncol 31:676–683CrossRefPubMed Matsutani M (2004) Clinical management of primary central nervous system germ cell tumors. Semin Oncol 31:676–683CrossRefPubMed
11.
go back to reference Brandes A, Pasetto L, Monfardini S (2000) The treatment of cranial germ cell tumours. Cancer Treat Rev 26:233–242CrossRefPubMed Brandes A, Pasetto L, Monfardini S (2000) The treatment of cranial germ cell tumours. Cancer Treat Rev 26:233–242CrossRefPubMed
12.
go back to reference Fujimaki T, Matsutani M et al (1994) CT and MRI features of intrcranial germ cell tumors. J Neurooncol 19:217–226CrossRefPubMed Fujimaki T, Matsutani M et al (1994) CT and MRI features of intrcranial germ cell tumors. J Neurooncol 19:217–226CrossRefPubMed
13.
14.
go back to reference Robertson P, DaRosso R, Allen J (1997) Improved prognosis of intracranial non-germinoma germ cell tumors with multimodality therapy. J Neurooncol 32:71–80CrossRefPubMed Robertson P, DaRosso R, Allen J (1997) Improved prognosis of intracranial non-germinoma germ cell tumors with multimodality therapy. J Neurooncol 32:71–80CrossRefPubMed
15.
go back to reference Jubran R, Finlay J (2005) Central nervous system germ cell tumors: controversies in diagnosis and treatment. Oncology 19(6):705–710PubMed Jubran R, Finlay J (2005) Central nervous system germ cell tumors: controversies in diagnosis and treatment. Oncology 19(6):705–710PubMed
16.
go back to reference Wolden S, Wara W et al (1995) Radiation therapy for primary intracranial germ-cell tumors. Int J Radiat Oncol 32(4):943–949CrossRef Wolden S, Wara W et al (1995) Radiation therapy for primary intracranial germ-cell tumors. Int J Radiat Oncol 32(4):943–949CrossRef
17.
go back to reference Haas-Kogan D, Missett B et al (2003) Radiation therapy for intracranial germ cell tumors. Int J Radiat Oncol 56(2):511–518CrossRef Haas-Kogan D, Missett B et al (2003) Radiation therapy for intracranial germ cell tumors. Int J Radiat Oncol 56(2):511–518CrossRef
18.
go back to reference Bokemeyer C, Kollmannsberger C et al (1999) First-line high dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: a multivariate and matched-pair analysis. J Clin Oncol 17(11):3450–3456PubMed Bokemeyer C, Kollmannsberger C et al (1999) First-line high dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: a multivariate and matched-pair analysis. J Clin Oncol 17(11):3450–3456PubMed
19.
go back to reference Ginsberg S, Kirshner J et al (1981) Systemic chemotherapy for a primary germ cell tumor of the brain: a pharmacokinetic study. Cancer Treat Rep 65:477–483PubMed Ginsberg S, Kirshner J et al (1981) Systemic chemotherapy for a primary germ cell tumor of the brain: a pharmacokinetic study. Cancer Treat Rep 65:477–483PubMed
20.
go back to reference Balmaceda C et al (2009) Intracranial and sacrococcygeal extragonadal germ cell tumors. In: Basow, DS (ed), UpToDate. Waltham, MA Balmaceda C et al (2009) Intracranial and sacrococcygeal extragonadal germ cell tumors. In: Basow, DS (ed), UpToDate. Waltham, MA
21.
go back to reference Kellie S et al (2004) Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol. J Clin Oncol 22:846–853CrossRefPubMed Kellie S et al (2004) Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol. J Clin Oncol 22:846–853CrossRefPubMed
Metadata
Title
Primary skull-based yolk-sac tumour: case report and review of central nervous system germ cell tumours
Authors
Raman Verma
Shawn Malone
Christina Canil
Gerard Jansen
Howard Lesiuk
Publication date
01-01-2011
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 1/2011
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-010-0215-8

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