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01-03-2017 | Case Report

Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT

Authors: Gul Ege Aktas, Nuray Can, Selin Soyluoglu Demir, Ali Sarıkaya

Published in: Nuclear Medicine and Molecular Imaging | Issue 1/2017

Abstract

A 69-year-old male smoker was referred to ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) with the indication of a suspicious solitary pulmonary nodule. FDG PET/CT determined a 2.5 × 2-cm soft-tissue lesion (SUVmax, 16.2) with spiculated margins in the hilum of the right lung. A 1-cm diameter lymphadenopathy on the right hilum with an SUVmax of 3.2 was also determined. Transbronchial biopsy of the right hilar lymphadenopathy did not reveal any malignant features in histopathologic examination, and it was determined to be reactive. The patient underwent a right upper lobe segmentectomy, and the histopathologic evaluation revealed that the tumor was a primary lymphoepithelioma-like carcinoma (LELC) of the lung with negative Epstein-Barr virus (EBV) on in situ hybridization studies. In this case report, we mainly focus on the FDG avidity of this very rare kind of tumor comparatively with previous reports and possible explanations of discordancy in FDG avidity in relation to histopathologic characteristics.

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Title: Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT
Authors: Gul Ege Aktas
Nuray Can
Selin Soyluoglu Demir
Ali Sarıkaya
Publication date: 01-03-2017
Publisher: Springer Berlin Heidelberg
Published in: Nuclear Medicine and Molecular Imaging / Issue 1/2017
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI: https://doi.org/10.1007/s13139-016-0428-7

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Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT

Abstract

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