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01-03-2007 | Case Report

Primary mediastinal anaplastic alk-1-positive large-cell lymphoma of T/NK-cell type expressing CD20

Authors: J. Gonin, H. Kadiri, S. Bensaci, A. Le Tourneau, T. J. Molina, J. Diebold, D. J. Abdellouche, J. Audouin

Published in: Virchows Archiv | Issue 3/2007

Abstract

We describe an unusual case of ALK-1-positive primary mediastinal lymphoma with the morphology of an anaplastic large-cell lymphoma (ALCL) of T/NK cell type but expressing CD20. This tumour had T/NK morphology and immunophenotype, as demonstrated by its expression of CD30, EMA, ALK-1, CD7 and TiA-1 and the lack of expression of B-cell markers other than CD20. The significance of such a co-expression of a B cell-associated antigen in a case of ALCL of T/NK cell type is discussed.

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Title: Primary mediastinal anaplastic alk-1-positive large-cell lymphoma of T/NK-cell type expressing CD20
Authors: J. Gonin
H. Kadiri
S. Bensaci
A. Le Tourneau
T. J. Molina
J. Diebold
D. J. Abdellouche
J. Audouin
Publication date: 01-03-2007
Publisher: Springer-Verlag
Published in: Virchows Archiv / Issue 3/2007
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-007-0371-1

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Primary mediastinal anaplastic alk-1-positive large-cell lymphoma of T/NK-cell type expressing CD20

Abstract

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Abstract

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