Primary Immunodeficiency Classification on Smartphone

Excerpt

Primary immunodeficiencies comprise at least 300 genetically defined single-gene inborn errors of immunity, presenting a broad spectrum of manifestations from susceptibility to infections to autoimmunity and inflammation. The International Union of Immunological Societies (IUIS) Expert Committee on Primary Immunodeficiency meets every other year to update the classification of human primary immunodeficiencies (PIDs). In recent years, two forms of classification have been published by the IUIS PID expert committee: a complete catalog of known PIDs subdivised in nine tables sharing a given pathogenesis, and a more user-friendly classification based on phenotype and laboratory results [1, 2]. …