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World Journal of Surgery

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Open Access 01-09-2018 | Original Scientific Report

Primary Hyperparathyroidism is Underdiagnosed and Suboptimally Treated in the Clinical Setting

Authors: Jacob Enell, Haytham Bayadsi, Ewa Lundgren, Joakim Hennings

Published in: World Journal of Surgery | Issue 9/2018

Abstract

Purpose

To evaluate whether patients presenting with laboratory results consistent with primary hyperparathyroidism (pHPT) are managed in accordance with guidelines.

Methods

The laboratory database at a hospital in Sweden, serving 127,000 inhabitants, was searched for patients with biochemically determined pHPT. During 2014, a total of 365 patients with biochemical laboratory tests consistent with pHPT were identified. Patients with possible differential diagnoses or other reasons for not being investigated according to international guidelines were excluded after scrutinizing records, after new blood tests, and clinical assessments by endocrine surgeons.

Results

Altogether, 92 patients had been referred to specialists and 82 had not. The latter group had lower serum calcium (median 2.54 mmol/L) and PTH (5.7 pmol/L). Out of these 82 cases, 9 patients were diagnosed with pHPT or had some sort of long-term follow-up planned as outpatients.

Conclusion

Primary hyperparathyroidism is overlooked and underdiagnosed in a number of patients in the clinical setting. It is important to provide local guidelines for the management of patients presenting with mild pHPT to ensure that these patients receive proper evaluation and follow-up according to current research.

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Title: Primary Hyperparathyroidism is Underdiagnosed and Suboptimally Treated in the Clinical Setting
Authors: Jacob Enell
Haytham Bayadsi
Ewa Lundgren
Joakim Hennings
Publication date: 01-09-2018
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 9/2018
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-018-4574-1

At a glance: The STEP trials

Springer Medicine

Primary Hyperparathyroidism is Underdiagnosed and Suboptimally Treated in the Clinical Setting

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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