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Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2016

Open Access 01-12-2016 | Case report

Primary hyperparathyroidism in pregnancy treated with cinacalcet: a case report and review of the literature

Authors: Lara Vera, Silvia Oddo, Natascia Di Iorgi, Giorgio Bentivoglio, Massimo Giusti

Published in: Journal of Medical Case Reports | Issue 1/2016

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Abstract

Background

The efficacy and safety of various modes of medical treatment for primary hyperparathyroidism in pregnancy are largely unknown.

Case presentation

We report the case of a 34-year-old white woman with primary hyperparathyroidism symptomatic for nephrolithiasis. Her serum calcium was 3.15 mmol/l and parathyroid hormone was 109.0 ng/L. Neck imaging found no pathological parathyroid tissue. Cinacalcet and cholecalciferol were started. She became pregnant 17 months later. The calcimimetic was stopped. During pregnancy, she was admitted for hydration administered intravenously two to three times per week. In her 24th week of pregnancy, cinacalcet was restarted. In her 32nd week, a cesarean section was carried out as planned.

Conclusions

Only three cases of primary hyperparathyroidism in women on cinacalcet therapy in pregnancy have been published in the literature. In the present case, hydration was useful in controlling serum calcium. Cinacalcet therapy helped to control serum calcium.
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Metadata
Title
Primary hyperparathyroidism in pregnancy treated with cinacalcet: a case report and review of the literature
Authors
Lara Vera
Silvia Oddo
Natascia Di Iorgi
Giorgio Bentivoglio
Massimo Giusti
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2016
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-016-1093-2

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