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Open Access 01-08-2009 | GI Image

Primary Hepatic Osteosarcoma

Authors: Atta Nawabi, Sidhartha Rath, Nicholas Nissen, Charles Forscher, Steven Colquhoun, Joseph Lee, Stephen Geller, Anna Wong, Andrew S. Klein

Published in: Journal of Gastrointestinal Surgery | Issue 8/2009

Excerpt

Extraskeletal osteosarcoma (EOS) is a rare entity. Most human cases have been described in the soft tissues of the limb.1 Primary hepatic osteosarcoma is extremely uncommon with only seven cases reported in the world’s literature. Of these cases, no patient survived more than 8 weeks from the time of diagnosis. We describe a young patient with a symptomatic primary hepatic osteosarcoma that was successfully treated by surgical resection and adjuvant chemotherapy. She is alive and tumor free 3 years after surgery. …

Allan CJ, Soule EH. Osteogenic sarcoma of the somatic soft tissues: clinicopathologic study of 26 cases and review of literature. Cancer 1971;27(5):1121–1133. doi:10.1002/1097-0142(197105)27:5<1121::AID-CNCR2820270519>3.0.CO;2-3.CrossRefPubMed

Marina N, Gebhardt M, Teot L, et al. Biology and therapeutic advances for pediatric osteosarcoma. Oncologist 2004;9:422–441. doi:10.1634/theoncologist.9-4-422.CrossRefPubMed

Bane BL, Evans HL, Ro JY, et al. Extraskeletal osteosarcoma, a clinicopathologic review of 26 cases. Cancer 1990;65:2762–2770. doi:10.1002/1097-0142(19900615)65:12<2762::AID-CNCR2820651226>3.0.CO;2-K.CrossRefPubMed

Momoi H, Wada Y, Sarumaru S, et al. Primary osteosarcoma of the breast. Breast Cancer 2004;11(4):396–400. doi:10.1007/BF02968048.CrossRefPubMed

Olgyai G, Horváth V, Kocsis J, et al. Extraskeletal osteosarcoma in the gallbladder. Magy Seb 2003;56(2):57–60.PubMed

Choudur HN, Munk PL, Nielson TO, Ryan AG. Primary mesenteric extraskeletal osteosarcoma in the pelvic cavity. Skeletal Radiol 2005;34(10):649–652. doi:10.1007/s00256-005-0909-8.CrossRefPubMed

Shimazu K, Funata N, Yamamoto Y, Mori T. Primary osteosarcoma arising in the colon: report of a case. Dis Colon Rectum 2001;44(9):1367–1370. doi:10.1007/BF02234799.CrossRefPubMed

Govender D, Raghubar KN. Primary hepatic osteosarcoma: case report and literature review. Pathology 1998;30:323–325. doi:10.1080/00313029800169556.CrossRefPubMed

Trowell JE, Arkell DG. Osteosarcoma of thyroid gland. J Pathol 1976;119:123–127. doi:10.1002/path.1711190208.CrossRefPubMed

10.

Axelrod R, Naidech HJ, Myers J, Steinberg A. Primary osteosarcoma of the kidney. Cancer 1978;41(2):724–727. doi:10.1002/1097-0142(197802)41:2<724::AID-CNCR2820410244>3.0.CO;2-N.CrossRefPubMed

11.

Ishak KG. Mesenchymal tumors of the liver. In Okuda K, Peters RL, eds. Hepatocellular carcinoma. New York: Wiley, 1976, pp 247–307.

12.

Stocker JT, Ishak KG. Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. Cancer 1978;42:336–348. doi:10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V.CrossRefPubMed

13.

Von Hochstetter AR, Hättenschwiler J, Vogt M. Primary osteosarcoma of the liver. Cancer 1987;60:2312–2317. doi:10.1002/1097-0142(19871101)60:9<2312::AID-CNCR2820600933>3.0.CO;2-W.CrossRef

14.

Sumiyoshi A, Niho Y. Primary osteogenic sarcoma of the liver: report of an autopsy case. Acta Pathol Jpn 1971;21:305–312.PubMed

15.

Boldt C, Pabst U, Nitsche R, Bürrig KF. Primary osteosarcoma of the liver. Case report and literature review. Pathologe 1999;20(6):359–364. doi:10.1007/s002920050372.CrossRefPubMed

16.

Kitayama Y, Sugimura H, Arai T, Nagamatsu K, Kino I. Primary osteosarcoma arising from cirrhotic liver. Pathol Int 1995;45(4):320–325. doi:10.1111/j.1440-1827.1995.tb03464.x.CrossRefPubMed

17.

Liony C, Lemarchand P, Manchon ND, et al. A case of primary osteosarcoma of the liver. Gastroenterol Clin Biol 1990;14(12):1003–1006.PubMed

18.

Hatori M, Hosaka M, Watanabe M, et al. Osteosarcoma in a patient with neurofibromatosis type 1: a case report and review of the literature. Tohoku J Exp Med 2006;208(4):343–348. doi:10.1620/tjem.208.343.CrossRefPubMed

19.

Patnaik AK, Kuy SK, Johnson JF. Extraskeletal osteosarcoma of the liver in a dog. J Small Anim Pract 1976;17:365–370. doi:10.1111/j.1748-5827.1976.tb06972.x.CrossRefPubMed

20.

Jeraj K, Yano B, Osborn CA. Primary hepatic osteosarcoma in dog. J Am Vet Med Assoc 1981;179:1000–1003.PubMed

Title: Primary Hepatic Osteosarcoma
Authors: Atta Nawabi
Sidhartha Rath
Nicholas Nissen
Charles Forscher
Steven Colquhoun
Joseph Lee
Stephen Geller
Anna Wong
Andrew S. Klein
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 8/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-009-0852-4

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Primary Hepatic Osteosarcoma

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