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Indian Journal of Hematology and Blood Transfusion

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01-06-2015 | Case Report

Primary Follicular Lymphoma of the Breast: A Rare Clinical Entity Diagnosed Using Tissue Flow Cytometry

Authors: Shivani Sharma, Pranav Dorwal, Ritesh Sachdev, Amit Pande, Neetu Tyagi, Dharmendra Jain, Vimarsh Raina

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 2/2015

Excerpt

Primary breast lymphomas are a rare entity and constitute less than 1 % of all the non-Hodgkin’s lymphomas, <0.5 % of all breast malignancies and <5 % of extranodal lymphomas [1]. The predominant type of primary breast lymphoma is Diffuse Large B cell Lymphoma (DLBCL), while Follicular Lymphoma (FL) is a still rarer entity. In the study conducted by International Extranodal Lymphoma Study Group (IELSG), on Primary Breast Lymphomas, FL constitute 12.9 % of total 278 cases [1]. …

Martinelli G, Ryan G, Seymour JF, Nassi L et al (2009) Primary follicular and marginal zone lymphoma of the breast: clinical features, prognostic factors and outcome: a study by International extranodal lymphoma study group. Ann Oncol 20(12):1993–2000CrossRefPubMed

Ray S, Craig FE, Swerdlow SH (2005) Abnormal patterns of antigen expression in follicular lymphoma. Am J Clin Pathol 124:576–583CrossRefPubMed

Topalovski M, Crisan D, Mattson JC (1999) Lymphoma of the breast: a clinicopathologic study of primary and secondary cases. Arch Pathol Lab Med 123:1208–1218PubMed

Swart GJ, Wright C, Brundyn K, Mansvelt E et al (2007) Fine needle aspiration biopsy and flow Cytometry in the diagnosis of lymphoma. Transfus Apheres Sci 37(1):71–79CrossRef

Cornfield DB, Mitchell DM, Almasri NM, Anderson JB et al (2000) Follicular lymphoma can be distinguished from benign follicular hyperplasia by flow Cytometry using simultaneous staining of cytoplasmic bcl-2 and cell surface CD20. Am J Clin Pathol 114:258–263CrossRefPubMed

Mourad WA, Rawas F, Shoukri M, Tbakhi A et al (2006) Grading of follicular lymphoma using flow cytometry. Ann Saudi Med 26(3):205–210

Title: Primary Follicular Lymphoma of the Breast: A Rare Clinical Entity Diagnosed Using Tissue Flow Cytometry
Authors: Shivani Sharma
Pranav Dorwal
Ritesh Sachdev
Amit Pande
Neetu Tyagi
Dharmendra Jain
Vimarsh Raina
Publication date: 01-06-2015
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 2/2015
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-014-0463-4

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