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Virchows Archiv
Published in: Virchows Archiv 2/2008

01-02-2008 | Case Report

Primary clear cell meningioma of the orbit mimicking a metastatic carcinoma: usefulness of immunohistochemistry and cytogenetic analysis

Authors: Maxime Benchetritt, Véronique Hofman, Elodie Long, Guillaume Odin, Elodie Basc, Basile Pasquier, Florence Pedeutour, Paul Hofman

Published in: Virchows Archiv | Issue 2/2008

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Abstract

Clear cell meningiomas (CCM) are rare tumors of the nervous system that usually occur in young patients and display high recurrence rates and potentially aggressive behavior. In this report, we describe a primary CCM of the orbit in an 84-year-old man with a previous history of a clear cell carcinoma of the kidney. Histologically, the tumor demonstrated a sheet-like proliferation of clear polygonal cells. Differential diagnosis includes metastasis of clear cell carcinomas. Immunohistochemistry, by showing that tumor cells expressed vimentin, epithelial membrane antigen, and progesterone antigens, and cytogenetic analysis, by identifying a monosomy 22, confirmed the diagnosis of CCM.
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Metadata
Title
Primary clear cell meningioma of the orbit mimicking a metastatic carcinoma: usefulness of immunohistochemistry and cytogenetic analysis
Authors
Maxime Benchetritt
Véronique Hofman
Elodie Long
Guillaume Odin
Elodie Basc
Basile Pasquier
Florence Pedeutour
Paul Hofman
Publication date
01-02-2008
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 2/2008
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-007-0519-z

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