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Published in: BMC Public Health 1/2011

Open Access 01-12-2011 | Research article

Preventable maternal mortality: Geographic/rural-urban differences and associated factors from the population-based maternal mortality surveillance system in China

Authors: Juan Liang, Li Dai, Jun Zhu, Xiaohong Li, Weiyue Zeng, He Wang, Qi Li, Mingrong Li, Rong Zhou, Yanping Wang

Published in: BMC Public Health | Issue 1/2011

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Abstract

Background

Most maternal deaths in developing countries can be prevented. China is among the 13 countries with the most maternal deaths; however, there has been a marked decrease in the maternal mortality ratio (MMR) over the last 3 decades. China's reduction in the MMR has contributed significantly to the global decline of the MMR. This study examined the geographic and rural-urban differences, time trends and related factors in preventable maternal deaths in China during 1996-2005, with the aim of providing reliable evidence for effective interventions.

Methods

Data were retrieved from the population-based maternal mortality surveillance system in China. Each death was reviewed by three committees to determine whether it was avoidable. The preventable maternal mortality ratio (PMMR), the ratios of PMMR (risk ratio, RR) and 95% confidence intervals (CI) were used to analyze regional disparities (coastal, inland and remote regions) and rural-urban variations. Time trends in the MMR, along with underlying causes and associated factors of death, were also analysed.

Results

Overall, 86.1% of maternal mortality was preventable. The RR of preventable maternal mortality adjusted by region was 2.79 (95% CI 2.42-3.21) and 2.38 (95% CI: 2.01-2.81) in rural areas compared to urban areas during the 1996-2000 and 2001-2005 periods, respectively. Meanwhile, the RR was the highest in remote areas, which was 4.80(95%CI: 4.10-5.61) and 4.74(95%CI: 3.86-5.83) times as much as that of coastal areas. Obstetric haemorrhage accounted for over 50% of preventable deaths during the 2001-2005 period. Insufficient information about pregnancy among women in remote areas and out-of-date knowledge and skills of health professionals and substandard obstetric services in coastal regions were the factors frequently associated with MMR.

Conclusions

Preventable maternal mortality and the distribution of its associated factors in China revealed obvious regional differences. The PMMR was higher in underdeveloped regions. In future interventions in remote and inland areas, more emphasis should be placed on improving women's ability to utilize healthcare services, enhancing the service capability of health institutions, and increasing the accessibility of obstetric services. These approaches will effectively lower PMMR in those regions and narrow the gap among the different regions.
Literature
1.
go back to reference United Nations: Implementation of the United Nations Millennium Declaratio. 2002, Report of the Secretary General United Nations: Implementation of the United Nations Millennium Declaratio. 2002, Report of the Secretary General
2.
go back to reference WHO, UNICEF, UNFPA: Maternal mortality in 2000: estimates developed by WHO, UNICEF, UNFP. 2004, Geneva: WHO WHO, UNICEF, UNFPA: Maternal mortality in 2000: estimates developed by WHO, UNICEF, UNFP. 2004, Geneva: WHO
3.
go back to reference Hill K, Thomas K, AbouZahr C, Walker N, Say L, Inoue M, Suzuki E: Estimates of maternal mortality worldwide between 1990 and 2005: an assessment of available data. Lancet. 2007, 370: 1311-1319. 10.1016/S0140-6736(07)61572-4.CrossRefPubMed Hill K, Thomas K, AbouZahr C, Walker N, Say L, Inoue M, Suzuki E: Estimates of maternal mortality worldwide between 1990 and 2005: an assessment of available data. Lancet. 2007, 370: 1311-1319. 10.1016/S0140-6736(07)61572-4.CrossRefPubMed
4.
go back to reference Hogan MC, Foreman KJ, Naghavi M, Ahn SY, Wang M, Makela SM, Lopez AD, Lozano R, Murray CJL: Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet. 2010, 375: 1609-1623. 10.1016/S0140-6736(10)60518-1.CrossRefPubMed Hogan MC, Foreman KJ, Naghavi M, Ahn SY, Wang M, Makela SM, Lopez AD, Lozano R, Murray CJL: Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet. 2010, 375: 1609-1623. 10.1016/S0140-6736(10)60518-1.CrossRefPubMed
5.
go back to reference Kilpatrick SJ, Crabtree KE, Kemp A, Geller S: Preventability of maternal deaths: comparison between Zambian and American referral hospitals. Obstet Gynecol. 2002, 100: 321-326. 10.1016/S0029-7844(02)02065-3.PubMed Kilpatrick SJ, Crabtree KE, Kemp A, Geller S: Preventability of maternal deaths: comparison between Zambian and American referral hospitals. Obstet Gynecol. 2002, 100: 321-326. 10.1016/S0029-7844(02)02065-3.PubMed
7.
go back to reference Lang CT, King JC: Maternal mortality in the United States. Best Pract Res Clin Obstet Gynaecol. 2008, 22: 517-531. 10.1016/j.bpobgyn.2007.10.004.CrossRefPubMed Lang CT, King JC: Maternal mortality in the United States. Best Pract Res Clin Obstet Gynaecol. 2008, 22: 517-531. 10.1016/j.bpobgyn.2007.10.004.CrossRefPubMed
8.
go back to reference Razum O, Jahn A, Blettner M, Reitmaier P: Trends in maternal mortality ratio among women of German and non-German nationality in West Germany, 1980-1996. Int J Epidemiol. 1999, 28: 919-924. 10.1093/ije/28.5.919.CrossRefPubMed Razum O, Jahn A, Blettner M, Reitmaier P: Trends in maternal mortality ratio among women of German and non-German nationality in West Germany, 1980-1996. Int J Epidemiol. 1999, 28: 919-924. 10.1093/ije/28.5.919.CrossRefPubMed
9.
go back to reference Schutte J, Steegers E, Schuitemaker N, Santema J, de Boer K, Pel M, Vermeulen G, Visser W, van Roosmalen J, the Netherlands Maternal Mortality Committee: Rise in maternal mortality in the Netherlands. BJOG. 2010, 117: 399-406. 10.1111/j.1471-0528.2009.02382.x.CrossRefPubMed Schutte J, Steegers E, Schuitemaker N, Santema J, de Boer K, Pel M, Vermeulen G, Visser W, van Roosmalen J, the Netherlands Maternal Mortality Committee: Rise in maternal mortality in the Netherlands. BJOG. 2010, 117: 399-406. 10.1111/j.1471-0528.2009.02382.x.CrossRefPubMed
10.
go back to reference Gonzalez R, Requejo JH, Nien JK, Merialdi M, Bustreo F, Betran AP: Tackling health inequities in Chile: maternal, newborn, infant, and child mortality between 1990 and 2004. Am J Public Health. 2009, 99: 1220-1226. 10.2105/AJPH.2008.143578.CrossRefPubMedPubMedCentral Gonzalez R, Requejo JH, Nien JK, Merialdi M, Bustreo F, Betran AP: Tackling health inequities in Chile: maternal, newborn, infant, and child mortality between 1990 and 2004. Am J Public Health. 2009, 99: 1220-1226. 10.2105/AJPH.2008.143578.CrossRefPubMedPubMedCentral
11.
go back to reference Ronsmans C, Graham WJ: Maternal mortality: who, when, where, and why. Lancet. 2006, 368: 1189-200. 10.1016/S0140-6736(06)69380-X.CrossRefPubMed Ronsmans C, Graham WJ: Maternal mortality: who, when, where, and why. Lancet. 2006, 368: 1189-200. 10.1016/S0140-6736(06)69380-X.CrossRefPubMed
12.
go back to reference UNICEF, WHO, UNFPA: Joint review of the maternal and child survival strategy in China. 2006, Beijing: UNICEF UNICEF, WHO, UNFPA: Joint review of the maternal and child survival strategy in China. 2006, Beijing: UNICEF
13.
go back to reference Gao J, Qian J, Tang S, Eriksson B, Blas E: Health equity in transition from planned to market economy in China. Health Policy Plan. 2002, 17 (suppl 1): 20-29. 10.1093/heapol/17.suppl_1.20.CrossRefPubMed Gao J, Qian J, Tang S, Eriksson B, Blas E: Health equity in transition from planned to market economy in China. Health Policy Plan. 2002, 17 (suppl 1): 20-29. 10.1093/heapol/17.suppl_1.20.CrossRefPubMed
14.
go back to reference Rudan I, Chan KY, Zhang JSF, Theodoratou E, Feng XL, Salomon JA, Lawn JE, Cousens S, Black RE, Guo Y, Campbell H: Causes of deaths in children younger than 5 years in China in 2008. Lancet. 2010, 375: 1083-1089. 10.1016/S0140-6736(10)60060-8.CrossRefPubMed Rudan I, Chan KY, Zhang JSF, Theodoratou E, Feng XL, Salomon JA, Lawn JE, Cousens S, Black RE, Guo Y, Campbell H: Causes of deaths in children younger than 5 years in China in 2008. Lancet. 2010, 375: 1083-1089. 10.1016/S0140-6736(10)60060-8.CrossRefPubMed
15.
go back to reference Wang YP, Miao L, Dai L, He CH, Li XH, Li MR, Zhou GX, Zhu J, Liang J: A study on ruraleurban differences in neonatal mortality rate in China, 1996-2006. J Epidemiol Community Health. 2010, 64: 935-936. 10.1136/jech.2009.090910.CrossRef Wang YP, Miao L, Dai L, He CH, Li XH, Li MR, Zhou GX, Zhu J, Liang J: A study on ruraleurban differences in neonatal mortality rate in China, 1996-2006. J Epidemiol Community Health. 2010, 64: 935-936. 10.1136/jech.2009.090910.CrossRef
16.
go back to reference Rao K, Chen Y, Tian M: Research on the classification of health status in China. Chinese Journal of Health Statistics. 1989, 6: 12-17. [In Chinese] Rao K, Chen Y, Tian M: Research on the classification of health status in China. Chinese Journal of Health Statistics. 1989, 6: 12-17. [In Chinese]
17.
go back to reference Lin LM, Liu YL, Mi J, Liu JJ, Feng SY, Zhang S: A survey of deaths of children under the age of 5 years in China. Chin J Pediatr. 1994, 32: 149-152. [In Chinese] Lin LM, Liu YL, Mi J, Liu JJ, Feng SY, Zhang S: A survey of deaths of children under the age of 5 years in China. Chin J Pediatr. 1994, 32: 149-152. [In Chinese]
18.
go back to reference Ministry of Health: China Health Statistics Yearbook 2005. 2006, Beijing: Ministry of Health, PRC, [In Chinese] Ministry of Health: China Health Statistics Yearbook 2005. 2006, Beijing: Ministry of Health, PRC, [In Chinese]
19.
go back to reference Li J, Luo C, Deng R, Jacoby P, de Klerk N: Maternal mortality in Yunnan, China: recent trends and associated factors. BJOG. 2007, 114: 865-874. 10.1111/j.1471-0528.2007.01362.x.CrossRefPubMed Li J, Luo C, Deng R, Jacoby P, de Klerk N: Maternal mortality in Yunnan, China: recent trends and associated factors. BJOG. 2007, 114: 865-874. 10.1111/j.1471-0528.2007.01362.x.CrossRefPubMed
20.
go back to reference Berg CJ, Harper MA, Atkinson SM, Bell EA, Brown HL, Hage ML, Mitra AG, Moise KJ, Callaghan WM: Preventability of pregnancy-related deaths, results of a state-wide review. Obstet Gynecol. 2005, 106: 1228-1234. 10.1097/01.AOG.0000187894.71913.e8.CrossRefPubMed Berg CJ, Harper MA, Atkinson SM, Bell EA, Brown HL, Hage ML, Mitra AG, Moise KJ, Callaghan WM: Preventability of pregnancy-related deaths, results of a state-wide review. Obstet Gynecol. 2005, 106: 1228-1234. 10.1097/01.AOG.0000187894.71913.e8.CrossRefPubMed
21.
go back to reference World Health Organization: Beyond the numbers: reviewing maternal deaths and complications to make pregnancy safer. 2004, Geneva: WHO World Health Organization: Beyond the numbers: reviewing maternal deaths and complications to make pregnancy safer. 2004, Geneva: WHO
22.
go back to reference World Health Organization: International Statistical Classification of Diseases and Related Health Problem (ICD-10). 1993, Geneva, Switzerland: WHO, 10th rev World Health Organization: International Statistical Classification of Diseases and Related Health Problem (ICD-10). 1993, Geneva, Switzerland: WHO, 10th rev
23.
go back to reference Ruan RS: Epidemiology Principles and Methods. 2004, Chengdu: Sichuan University Press, 1 Ruan RS: Epidemiology Principles and Methods. 2004, Chengdu: Sichuan University Press, 1
24.
go back to reference Agresti A: Categorical Data Analysis. 1990, New York: John Wiley and Sons, Inc Agresti A: Categorical Data Analysis. 1990, New York: John Wiley and Sons, Inc
25.
go back to reference Nagaya K, Fetters MD, Ishikawa M, Kabo T, Koyanagi T, Saito Y: Causes of maternal mortality in Japan. JAMA. 2000, 283: 2661-2667. 10.1001/jama.283.20.2661.CrossRefPubMed Nagaya K, Fetters MD, Ishikawa M, Kabo T, Koyanagi T, Saito Y: Causes of maternal mortality in Japan. JAMA. 2000, 283: 2661-2667. 10.1001/jama.283.20.2661.CrossRefPubMed
26.
go back to reference De Lange TE, Budde MP, Heard AR, Tucker G, Kennare R, Dekker GA: Avoidable risk factors in perinatal deaths: A perinatal audit in South Australia. Aust N Z J Obstet Gynaecol. 2008, 48: 50-57. 10.1111/j.1479-828X.2007.00801.x.CrossRefPubMed De Lange TE, Budde MP, Heard AR, Tucker G, Kennare R, Dekker GA: Avoidable risk factors in perinatal deaths: A perinatal audit in South Australia. Aust N Z J Obstet Gynaecol. 2008, 48: 50-57. 10.1111/j.1479-828X.2007.00801.x.CrossRefPubMed
27.
go back to reference Ozumba BC, Nwogu-Ikojo EE: Avoidable maternal mortality in Enugu, Nigeria. Public Health. 2008, 122: 354-360. 10.1016/j.puhe.2007.04.018.CrossRefPubMed Ozumba BC, Nwogu-Ikojo EE: Avoidable maternal mortality in Enugu, Nigeria. Public Health. 2008, 122: 354-360. 10.1016/j.puhe.2007.04.018.CrossRefPubMed
28.
go back to reference Alves SV: Maternal mortality in pernambuco, Brazil: what has changed in ten years?. Reprod Health Matters. 2007, 15: 134-144. 10.1016/S0968-8080(07)30326-1.CrossRefPubMed Alves SV: Maternal mortality in pernambuco, Brazil: what has changed in ten years?. Reprod Health Matters. 2007, 15: 134-144. 10.1016/S0968-8080(07)30326-1.CrossRefPubMed
29.
go back to reference State Statistics Bureau: China Statistical Yearbook 2005. 2006, Beijing: State Statistics Bureau, PRC, [In Chinese] State Statistics Bureau: China Statistical Yearbook 2005. 2006, Beijing: State Statistics Bureau, PRC, [In Chinese]
30.
go back to reference Liang J, Zhu J, Li MR, Wang YP, Dai L, He CH, Li Q: Analysis of epidemiological characteristics of maternal mortality in target counties in 2007. Mod Prev Med. 2009, 36: 1851-1860. [In Chinese] Liang J, Zhu J, Li MR, Wang YP, Dai L, He CH, Li Q: Analysis of epidemiological characteristics of maternal mortality in target counties in 2007. Mod Prev Med. 2009, 36: 1851-1860. [In Chinese]
31.
go back to reference Bodker B, Hvidman L, Weber T, Moller M, Aarre A, Nielsen KM, Sorensen JL: Maternal deaths in Denmark 2002-2006. Acta Obstet Gynecol Scand. 2009, 88: 556-562. 10.1080/00016340902897992.CrossRefPubMed Bodker B, Hvidman L, Weber T, Moller M, Aarre A, Nielsen KM, Sorensen JL: Maternal deaths in Denmark 2002-2006. Acta Obstet Gynecol Scand. 2009, 88: 556-562. 10.1080/00016340902897992.CrossRefPubMed
32.
go back to reference Khan KS, Wojdyla D, Say L, Gulmezoglu AM, Van Look PFA: WHO analysis of causes of maternal death: a systematic review. Lancet. 2006, 367: 1066-1074. 10.1016/S0140-6736(06)68397-9.CrossRefPubMed Khan KS, Wojdyla D, Say L, Gulmezoglu AM, Van Look PFA: WHO analysis of causes of maternal death: a systematic review. Lancet. 2006, 367: 1066-1074. 10.1016/S0140-6736(06)68397-9.CrossRefPubMed
33.
go back to reference Haixia Lu: Rational thoughts on imbalanced allocation of China's rural basic health resources. Chinese Health Economics. 2009, 28: 38-42. [In Chinese] Haixia Lu: Rational thoughts on imbalanced allocation of China's rural basic health resources. Chinese Health Economics. 2009, 28: 38-42. [In Chinese]
34.
go back to reference Rong Luo, Qi Yang, Xi Jin: Analysis on medical and health personnel collocation of WCH of province and prefecture and county. Maternal & Child health care of China. 2007, 22: 2313-2315. [In Chinese] Rong Luo, Qi Yang, Xi Jin: Analysis on medical and health personnel collocation of WCH of province and prefecture and county. Maternal & Child health care of China. 2007, 22: 2313-2315. [In Chinese]
35.
go back to reference Huang A, Xi J, Luo R, Mu T, Xiang M, Wang C, Pan X: The situation of human resources in the county level maternal and children health care institutes. Chin J Women Child Health. 2010, 11: 130-133. [In Chinese] Huang A, Xi J, Luo R, Mu T, Xiang M, Wang C, Pan X: The situation of human resources in the county level maternal and children health care institutes. Chin J Women Child Health. 2010, 11: 130-133. [In Chinese]
36.
go back to reference Liang J, Wang YP, Wu YQ, Zhou GX, Zhun J, Dai L, Miao L: Maternal mortality in rural areas in China. Journal of Sichuan University (Medical Science Edition). 2004, 35: 258-60. [In Chinese] Liang J, Wang YP, Wu YQ, Zhou GX, Zhun J, Dai L, Miao L: Maternal mortality in rural areas in China. Journal of Sichuan University (Medical Science Edition). 2004, 35: 258-60. [In Chinese]
37.
go back to reference Fuqiang Cui, Purhati , Hadler Stephen, Xiaofeng Liang: Analysis on new born hepatitis B immunization coverage and pregnant women hospital delivery rate in different regions. Chinese journal of vaccines and immunization. 2007, 13: 1-3. [In Chinese] Fuqiang Cui, Purhati , Hadler Stephen, Xiaofeng Liang: Analysis on new born hepatitis B immunization coverage and pregnant women hospital delivery rate in different regions. Chinese journal of vaccines and immunization. 2007, 13: 1-3. [In Chinese]
38.
go back to reference Zhu L, Qin M, Du L, Jia W, Yang Q, Walker M, Wen S: Comparison of maternal mortality between migrating population and permanent residents in Shanghai, China, 1996-2005. BJOG. 2009, 116: 401-407. 10.1111/j.1471-0528.2008.01979.x.CrossRefPubMed Zhu L, Qin M, Du L, Jia W, Yang Q, Walker M, Wen S: Comparison of maternal mortality between migrating population and permanent residents in Shanghai, China, 1996-2005. BJOG. 2009, 116: 401-407. 10.1111/j.1471-0528.2008.01979.x.CrossRefPubMed
Metadata
Title
Preventable maternal mortality: Geographic/rural-urban differences and associated factors from the population-based maternal mortality surveillance system in China
Authors
Juan Liang
Li Dai
Jun Zhu
Xiaohong Li
Weiyue Zeng
He Wang
Qi Li
Mingrong Li
Rong Zhou
Yanping Wang
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2011
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-11-243

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