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International Urogynecology Journal

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01-10-2011 | Original Article

Prevalence of “low-count” bacteriuria in female urinary incontinence versus continent female controls: a cross-sectional study

Authors: Colin A. Walsh, Anne Siddins, Katrina Parkin, Chinmoy Mukerjee, Kate H. Moore

Published in: International Urogynecology Journal | Issue 10/2011

Abstract

Introduction and hypothesis

Older studies suggesting an association between detrusor overactivity and bacteriuria used an outdated microbiological threshold. We hypothesised that bacteriuria ≥10³ CFU/ml would be more prevalent in women with urinary incontinence than continent controls.

Methods

A prospective, cross-sectional study of prevalence of bacteriuria ≥10³ colony-forming units (CFU)/ml on catheter specimens. Sample estimates suggested 62 women per arm would yield 80% power. Multivariate regression analysis was performed using risk factors including, age, diabetes, menopausal status, sexual activity and cystocele.

Results

Among 213 participants, bacteriuria ≥10³ CFU/ml was more prevalent in incontinent women than continent controls (odds ratio [OR] 4.06; p = 0.036). Two thirds of bacteriuric specimens grew “low-count” bacteriuria. On multivariate analysis, only cystocele ≥ grade II was independently associated with bacteriuria (p = 0.025). On sub-analysis by diagnosis, the only significant finding was with bladder oversensitivity (OR 13.8; p = 0.0017).

Conclusions

Bacteriuria, including “low-count” bacteriuria, is more prevalent in urinary incontinence when compared to continent female controls.

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Title: Prevalence of “low-count” bacteriuria in female urinary incontinence versus continent female controls: a cross-sectional study
Authors: Colin A. Walsh
Anne Siddins
Katrina Parkin
Chinmoy Mukerjee
Kate H. Moore
Publication date: 01-10-2011
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 10/2011
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-011-1506-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prevalence of “low-count” bacteriuria in female urinary incontinence versus continent female controls: a cross-sectional study

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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