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World Journal of Urology
Published in: World Journal of Urology 4/2014

01-08-2014 | Original Article

Prevalence of baseline chronic kidney disease in 2,769 Chinese patients with renal cancer: Nephron-sparing treatment is still underutilized

Authors: Kai-wei Yang, Geng-yan Xiong, Xue-song Li, Yuan Tang, Qi Tang, Cui-jian Zhang, Zhi-song He, Li-qun Zhou

Published in: World Journal of Urology | Issue 4/2014

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Abstract

Purpose

To evaluate the prevalence of baseline chronic kidney disease (CKD) in a large cohort of patients with renal masses in a single Chinese institution. Estimated glomerular filtration rate (eGFR) and CKD stage are more clinically relevant to predict the risk of morbidity and mortality in patients after nephrectomy. But, sCr reflects renal function poorly.

Methods

We retrospectively identified patients undergoing kidney surgery between January 2002 and June 2012. eGFR was calculated using the modification of diet in renal disease formulas modified based on Chinese people. CKD stages I–V were defined using the National Kidney Foundation definitions.

Results

A total of 2769 patients had adequate data available to calculate a preoperative eGFR (mL/min/1.73m2) with renal cancer confirmed by pathology. Of all patients, 97.7 % awaiting surgery at our institution had a “normal” baseline sCr (≤1.4 mg/dL), and 3.2 % of patients had CKD stage III or worse. Of the 401 patients ≥70 years old, 16.7 % (67/401) had CKD stage III.

Conclusion

Many patients with a seemingly normal sCr have CKD stage III or worse, especially in patients over 70 years old. Given the high prevalence of baseline CKD in patients with renal cancer, it is important to preserve renal parenchyma when treating them surgically.
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Metadata
Title
Prevalence of baseline chronic kidney disease in 2,769 Chinese patients with renal cancer: Nephron-sparing treatment is still underutilized
Authors
Kai-wei Yang
Geng-yan Xiong
Xue-song Li
Yuan Tang
Qi Tang
Cui-jian Zhang
Zhi-song He
Li-qun Zhou
Publication date
01-08-2014
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 4/2014
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-013-1178-0

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