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Published in: Journal of Cardiovascular Magnetic Resonance 1/2011

Open Access 01-12-2011 | Research

Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion

Authors: Rungroj Krittayaphong, Pairash Saiviroonporn, Thananya Boonyasirinant, Suthipol Udompunturak

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2011

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Abstract

Background

Some patients may have normal wall motion after myocardial infarction. The aim of this study was to determine the prevalence and prognosis of patients with myocardial scar in the absence of abnormal wall motion. We studied patients with suspected or known coronary artery disease (CAD) who were referred for cardiovascular magnetic resonance (CMR) for the assessment of global and regional cardiac function and late gadolinium enhancement (LGE) and had normal left ventricular wall motion. Prognostic value was determined by the occurrence of hard endpoints (cardiac death and nonfatal myocardial infarction) and major adverse cardiac events (MACE) which also included hospitalization due to unstable angina or heart failure or life threatening ventricular arrhythmia.

Results

A total 1148 patients (70.3%) were studied. LGE was detected in 104 patients (9.1%). Prevalence of LGE increased in patients with increased left ventricular mass. Average follow-up time was 955 ± 542 days. LGE was the strongest predictor for hard endpoints and MACE.

Conclusion

LGE was detected in 9.1% of patients with suspected or known CAD and normal wall motion. LGE was the strongest predictor of significant cardiac events.
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Metadata
Title
Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion
Authors
Rungroj Krittayaphong
Pairash Saiviroonporn
Thananya Boonyasirinant
Suthipol Udompunturak
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Cardiovascular Magnetic Resonance / Issue 1/2011
Electronic ISSN: 1532-429X
DOI
https://doi.org/10.1186/1532-429X-13-2

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