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Open Access 01-06-2017 | Original Communication

Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data

Authors: Stéphanie Foulon, Géric Maura, Marie Dalichampt, François Alla, Marc Debouverie, Thibault Moreau, Alain Weill

Published in: Journal of Neurology | Issue 6/2017

Abstract

Data on the prevalence of multiple sclerosis (MS) in France are scarce. National and regional updated estimates are needed to better plan health policies. In this nationwide study, we provided estimates of the prevalence of MS in France in 2012 and mortality rate in 2013. MS cases were identified in the French national health insurance database (SNIIRAM-PMSI) using reimbursement data for disease-modifying treatment, long-term disease status for MS, disability pension for MS, and hospitalisation for MS (MS ICD-10 code: G35). We identified 99,123 MS cases, corresponding to an overall crude prevalence rate of 151.2 per 100,000 inhabitants [95% confidence interval (CI) 150.3–152.2]: 210.0 per 100,000 in women (95% CI 208.4–211.5) and 88.7 per 100,000 in men (95% CI 87.6–89.7). The overall prevalence rate was 155.6 per 100,000 inhabitants (95% CI 154.7–156.6) after standardization on the 2013-European population. We observed a prevalence gradient with a higher prevalence (190–200 per 100,000) in North-Eastern France and a lower prevalence in Southern and Western France (126–140). The crude mortality rate in 2013 was 13.7 per 1,000 MS cases (11.4 in women and 20.3 in men). The standardized mortality ratio was 2.56 (95% CI 2.41–2.72). Our results revise upwards the estimation of MS prevalence in France and confirm the excess mortality of MS patients compared to the general population.

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Title: Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data
Authors: Stéphanie Foulon
Géric Maura
Marie Dalichampt
François Alla
Marc Debouverie
Thibault Moreau
Alain Weill
Publication date: 01-06-2017
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 6/2017
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-017-8513-0

At a glance: The STEP trials

Springer Medicine

Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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