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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2016

Open Access 01-12-2016 | Research article

Prevalence and distribution of ossification of the supra/interspinous ligaments in symptomatic patients with cervical ossification of the posterior longitudinal ligament of the spine: a CT-based multicenter cross-sectional study

Authors: Kanji Mori, Toshitaka Yoshii, Takashi Hirai, Akio Iwanami, Kazuhiro Takeuchi, Tsuyoshi Yamada, Shoji Seki, Takashi Tsuji, Kanehiro Fujiyoshi, Mitsuru Furukawa, Soraya Nishimura, Kanichiro Wada, Masao Koda, Takeo Furuya, Yukihiro Matsuyama, Tomohiko Hasegawa, Katsushi Takeshita, Atsushi Kimura, Masahiko Abematsu, Hirotaka Haro, Tetsuro Ohba, Masahiko Watanabe, Hiroyuki Katoh, Kei Watanabe, Hiroshi Ozawa, Haruo Kanno, Shiro Imagama, Zenya Ito, Shunsuke Fujibayashi, Masashi Yamazaki, Morio Matsumoto, Masaya Nakamura, Atsushi Okawa, Yoshiharu Kawaguchi

Published in: BMC Musculoskeletal Disorders | Issue 1/2016

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Abstract

Background

Supra/interspinous ligaments connect adjacent spinous processes and act as a stabilizer of the spine. As with other spinal ligaments, it can become ossified. However, few report have discussed ossification supra/interspinous ligaments (OSIL), so its epidemiology remains unknown. We therefore aimed to investigate the prevalence and distribution of OSIL in symptomatic patients with cervical ossification of the posterior longitudinal ligament (OPLL).

Methods

The participants of our study were symptomatic patients with cervical OPLL who were diagnosed by standard radiographs of the cervical spine. The whole spine CT data as well as clinical parameters such as age and sex were obtained from 20 institutions belong to the Japanese Multicenter Research Organization for Ossification of the Spinal Ligament (JOSL). The prevalence and distribution of OSIL and the association between OSIL and clinical parameters were reviewed. The sum of the levels involved by OPLL (OP-index) and OSIL (OSI-index) as well as the prevalence of ossification of the nuchal ligament (ONL) were also investigated.

Results

A total of 234 patients with a mean age of 65 years was recruited. The CT-based evidence of OSIL was noted in 68 (54 males and 14 females) patients (29%). The distribution of OSIL showed a significant thoracic preponderance. In OSIL-positive patients, single-level involvement was noted in 19 cases (28%), whereas 49 cases (72%) presented multi-level involvement. We found a significant positive correlation between the OP-index grade and OSI-index. ONL was noted at a significantly higher rate in OSIL-positive patients compared to negative patients.

Conclusions

The prevalence of OSIL in symptomatic patients with cervical OPLL was 29%. The distribution of OSIL showed a significant thoracic preponderance.
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Metadata
Title
Prevalence and distribution of ossification of the supra/interspinous ligaments in symptomatic patients with cervical ossification of the posterior longitudinal ligament of the spine: a CT-based multicenter cross-sectional study
Authors
Kanji Mori
Toshitaka Yoshii
Takashi Hirai
Akio Iwanami
Kazuhiro Takeuchi
Tsuyoshi Yamada
Shoji Seki
Takashi Tsuji
Kanehiro Fujiyoshi
Mitsuru Furukawa
Soraya Nishimura
Kanichiro Wada
Masao Koda
Takeo Furuya
Yukihiro Matsuyama
Tomohiko Hasegawa
Katsushi Takeshita
Atsushi Kimura
Masahiko Abematsu
Hirotaka Haro
Tetsuro Ohba
Masahiko Watanabe
Hiroyuki Katoh
Kei Watanabe
Hiroshi Ozawa
Haruo Kanno
Shiro Imagama
Zenya Ito
Shunsuke Fujibayashi
Masashi Yamazaki
Morio Matsumoto
Masaya Nakamura
Atsushi Okawa
Yoshiharu Kawaguchi
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2016
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-016-1350-y

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