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Critical Care
Published in: Critical Care 6/2013

01-12-2013 | Commentary

Preserving spontaneous breathing during mechanical ventilatory support: an old yet fascinating story

Authors: Enrico Calzia, Rolf Dembinski

Published in: Critical Care | Issue 6/2013

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Abstract

Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthermore, effectiveness in relation to the pathophysiology of respiratory failure is unclear. In this regard the experimental study by Saddy and colleagues reveals interesting insights into the pathophysiology of ventilator-induced injury. More important, their results raise important questions that should be evaluated in further studies.
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Powers SK, Wiggs MP, Sollanek KJ, Smuder AJ: Ventilator-induced diaphragm dysfunction: cause and effect. Am J Physiol Regul Integr Comp Physiol 2013, 305: R464-R477. 10.1152/ajpregu.00231.2013CrossRefPubMed
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Metadata
Title
Preserving spontaneous breathing during mechanical ventilatory support: an old yet fascinating story
Authors
Enrico Calzia
Rolf Dembinski
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2013
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc13120

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